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The Pharmacogenetics Of Opioid Pain Management, MaryAnne Ventura, Lauren Desko, Kimberly Gathers, Ashley Overy, David Kisor 2019 Ohio Northern University

The Pharmacogenetics Of Opioid Pain Management, Maryanne Ventura, Lauren Desko, Kimberly Gathers, Ashley Overy, David Kisor

Pharmacy and Wellness Review

High rates of interpatient variability in drug metabolism and drug response for nearly all medications lead to the hypothesis that assessment of an individual patient's genotype with respect to their ability metabolize certain drugs can be a useful tool in predicting a patient's responsiveness to certain medications. Evaluating patients using pharmacogenomics as a basis for assessment could allow pharmacists to decide which treatment options would be most efficacious in a given patient and, thereby, have significant impact in the clinical setting. This holds true especially in the case of prodrugs, which require in vivo activation to an active ...


Improvement In Mental Health Following Total Hip Arthroplasty: The Role Of Pain And Function, Uyen-Sa D. T. Nguyen, Thomas Perneger, Patricia D. Franklin, Christophe Barea, Pierre Hoffmeyer, Anne Lubbeke 2019 University of Massachusetts Medical School

Improvement In Mental Health Following Total Hip Arthroplasty: The Role Of Pain And Function, Uyen-Sa D. T. Nguyen, Thomas Perneger, Patricia D. Franklin, Christophe Barea, Pierre Hoffmeyer, Anne Lubbeke

Open Access Articles

BACKGROUND: Mental health has been shown to improve after total hip arthroplasty (THA). Little is known about the role of pain and function in this context. We assessed whether change in mental health was associated with improvement in pain and function 1 year post-surgery.

METHODS: This prospective study included patients enrolled in a THA registry from 2010 to 2014. We examined the mental component score (MCS) before and 1 year post-surgery, and 1-year change, in association with Western Ontario McMaster Universities (WOMAC) pain and function scores. All scores were normalized, ranging from 0 to 100 (larger score indicating better outcome ...


The Effect Of The Implementation Of A Quarterly Triad Tool In The Pain Clinic Setting On The Assessment And Mitigation Of Risks In Patients On Chronic Opioid Therapy, Caroline Asava 2019 Valparaiso University

The Effect Of The Implementation Of A Quarterly Triad Tool In The Pain Clinic Setting On The Assessment And Mitigation Of Risks In Patients On Chronic Opioid Therapy, Caroline Asava

Evidence-Based Practice Project Reports

The concurrent use of opioids and benzodiazepines (BZDs poses a formidable challenge for clinicians who manage chronic pain. While the escalating use of opioid analgesics for the treatment of chronic pain and the concomitant rise in opioid-related abuse and misuse are widely recognized trends, the contribution of combination use of BZDs, alcohol, and/or other sedative agents to opioid-related morbidity and mortality is underappreciated, even when these agents are used appropriately. Patients with chronic pain who use opioid analgesics along with BZDs have a defined increase in rates of adverse events, overdose, and death, warranting close monitoring. To improve patient ...


Pain-Related Fear: Metacognitive And Health Belief Predictors Of Cogniphobia, Maddison Miles 2019 James Madison University

Pain-Related Fear: Metacognitive And Health Belief Predictors Of Cogniphobia, Maddison Miles

Masters Theses

Individuals who have an unreasonable fear of headache pain or painful re-injury during cognitive exertion are said to suffer from a pain-related fear referred to as cogniphobia. Specifically, individuals high in cogniphobia avoid cognitive tasks in an attempt to reduce the risk of initiating or exacerbating headache-related pain. While health beliefs concerning pain-related fear have been examined through the concept of kinesiophobia, defined as the unreasonable fear of pain or painful re-injury during physical movement, little research has been done through a cognitive framework. The health anxiety beliefs, metacognitive factors, and negative thinking patterns related to cogniphobia remain unclear. This ...


Increasing Adult's Awareness Of The Importance Of End-Of-Life Care Discussions, Taylor Gardner 2019 California State University, Monterey Bay

Increasing Adult's Awareness Of The Importance Of End-Of-Life Care Discussions, Taylor Gardner

Capstone Projects and Master's Theses

For many American families, end-of-life care is often not discussed, until advanced illness or injury has fully disrupted everyday life. There are many benefits to discussing end-of-life care prior to any medical complications. Research has shown that individuals who plan their end-of-life processes with a hospice service provider and family members report a higher quality of death than individuals receiving common health care during their final six months of life. In order to make families and friends more comfortable with end-of-life discussions, I will conduct two one-hour educational sessions to students at California State University, Monterey Bay.


Health And Quality Of Life Of Children Undergoing Elective Surgery, Vivian Luong 2019 Chapman University

Health And Quality Of Life Of Children Undergoing Elective Surgery, Vivian Luong

Student Scholar Symposium Abstracts and Posters

Multiple studies have found that poorer health is associated with significantly lower quality of life when comparing children and adults with health conditions such as cancer, diabetes, asthma, and ADHD to their normal healthy counterparts. The relationship between health and quality of life, however, has yet to be examined in children who have undergone elective surgery. More than 5 million children in the U.S. undergo surgery each year. These children are often undergoing surgery for a number of health issues that may impede quality of life. Consequently, this study analyzes the effects of health on the quality of life ...


Seerratus Anterior Plane Block (Sapb) Improves Paine Control In Rib Fractures, Randy Kring, Peter Croft, David Mackenzie, Christina Wilson, Joseph Rappold, Tania D. Strout 2019 Maine Medical Center

Seerratus Anterior Plane Block (Sapb) Improves Paine Control In Rib Fractures, Randy Kring, Peter Croft, David Mackenzie, Christina Wilson, Joseph Rappold, Tania D. Strout

Maine Medical Center

Background:

•Trauma is a major cause of morbidity and mortality worldwide. Rib fractures are identified in at least 10% of all injured patients.

•Rib fractures can lead to significant respiratory complications, with pneumonia and respiratory failure occurring in up to 31% of patients with rib fractures. Early initiation of aggressive pain control and pulmonary hygiene with incentive spirometry are standard of care to prevent complications from developing.

•In the Emergency Department, patients with rib fractures typically receive systemic analgesia that is largely narcotic-based. This pain control strategy puts patients at risk for the side effects of narcotics such as constipation ...


Increasing Doses Of Intraoperative Hydromorphone Do Not Reduce Postoperative Pain, Craig S. Curry, Michael B. Henry, Wendy C. Craig, Janelle M. Richard, Denham S. Ward 2019 Maine Medical Center

Increasing Doses Of Intraoperative Hydromorphone Do Not Reduce Postoperative Pain, Craig S. Curry, Michael B. Henry, Wendy C. Craig, Janelle M. Richard, Denham S. Ward

Maine Medical Center

Introduction:

• Intermediate and long acting opioids are given intraoperatively to reduce pain during emergence from anesthesia.

• Recent evidence suggests that intraoperative opioids have inconsistent effects on nociception and pain in the immediate postoperative period.

• Multiple potent, short-acting opioids such as remifentanil, sufentanil and fentanyl have been shown to produce dose-related increases in pain scores and opioid consumption in the immediate postoperative recovery period.

• Intraoperative doses of longer acting opioids such as morphine and methadone6 have been shown to reduce pain scores and narcotic requirements in the immediate postoperative period.

• Hydromorphone is an intermediate duration narcotic which is commonly used intraoperatively ...


Influence Of Biomedical Risk Factors On Chronic Low Back Pain Among Women, Jennifer Kawi 2019 University of Nevada, Las Vegas

Influence Of Biomedical Risk Factors On Chronic Low Back Pain Among Women, Jennifer Kawi

Nursing Faculty Publications

Purpose Nurses and nurse practitioners are highly involved in managing patients with chronic low back pain (CLBP). Management remains challenging with persistent biomedical risk factors (e.g, high opioid use, Body Mass Index [BMI], chronic widespread pain). Due to pervasive pain care disparities among women, this quantitative pilot study evaluated biomedical risk factors among adult females with CLBP. Findings can assist in targeting risk factors to help address known undertreatment of pain in women. Methods This IRB-approved, descriptive, and cross-sectional study was conducted in a pain center to identify significant associations of relevant biomedical factors with pain/pain-related variables. Self-report ...


Low Back Pain, A Comprehensive Review: Pathophysiology, Diagnosis, And Treatment (Poster), Ivan Urits, Aaron Burshtein, Medha Sharma, Lauren Testa, Peter A. Gold, Vwaire Orhurhu, Omar Viswanath, Mark R. Jones, Moises A. Sidransky, Alan D. Kaye 2019 Harvard Medical School

Low Back Pain, A Comprehensive Review: Pathophysiology, Diagnosis, And Treatment (Poster), Ivan Urits, Aaron Burshtein, Medha Sharma, Lauren Testa, Peter A. Gold, Vwaire Orhurhu, Omar Viswanath, Mark R. Jones, Moises A. Sidransky, Alan D. Kaye

Senior Scholars Program

Purpose of Review: Low back pain encompasses three distinct sources: axial lumbosacral, radicular, and referred pain. Annually, the prevalence of low back pain in the general U.S. adult population is 10-30%, and the lifetime prevalence of U.S. adults is as high as 65-80%.

Recent Findings: Patient history, physical exam, and diagnostic testing are important components to accurate diagnosis and identification of patient pathophysiology. Etiologies of low back pain include myofascial pain, facet joint pain, sacroiliac joint pain, discogenic pain, and spinal stenosis, and failed back surgery. In chronic back pain patients, a multidisciplinary, logical approach to treatment is ...


Availability And Nursing Implementation Of Measurement Tools In The Co-Occurrence Of Depression And Chronic Pain: An Integrative Literature Review, Ashley Thomas 2019 DePaul University

Availability And Nursing Implementation Of Measurement Tools In The Co-Occurrence Of Depression And Chronic Pain: An Integrative Literature Review, Ashley Thomas

Grace Peterson Nursing Research Colloquium

Availability and Nursing Implementation of Measurement Tools in the Co-Occurrence of Depression and Chronic Pain: An Integrative Literature Review

Ashley Thomas

Faculty Sponsor: Barbara Harris

Background: There is high correlation between chronic pain and depression. They are seen throughout the literature to interact and feedback symptoms upon each other. However, there is not a comprehensive screening tool that assess both symptoms and not a clear indication of nursing responsibility in assessment of the co-occurrence.

Objectives: The purpose of this literature review is to create a comprehensive review of current research concerning the availability of screening tools that measure the co-occurrence ...


Trespassing Physical Boundaries: Transgression, Vulnerability And Resistance In Sarah Kane’S Blasted (1995), Paula Barba Guerrero, Ana Mª Manzanas Calvo 2019 University of Salamanca (Spain)

Trespassing Physical Boundaries: Transgression, Vulnerability And Resistance In Sarah Kane’S Blasted (1995), Paula Barba Guerrero, Ana Mª Manzanas Calvo

CLCWeb: Comparative Literature and Culture

Sarah Kane’s Blasted has been analyzed from various perspectives that address the layers of destruction it exposes. From the questioning of its title and meaning, to the unravelling of the protagonists’ abusive relationship, the analyses have emphasized the depiction of vulnerability as the defining human trait that Jean Ganteau observes in contemporary British literature. However, a key aspect has been overlooked in the critical response to the play: for Kane vulnerability does not equal helplessness, but rather stands in opposition to it. Hence, this article concentrates on how Blasted formulates a new understanding of vulnerability that fits Judith Butler ...


How Hugging Mom Teaches Me The Meaning Of Love And Perhaps Beyond, Ethan Trinh 2019 Georgia State University

How Hugging Mom Teaches Me The Meaning Of Love And Perhaps Beyond, Ethan Trinh

The Journal of Faith, Education, and Community

Hugging mom is unconventional in a traditional Vietnamese family. I write this piece to articulate my thoughts to describe different ways to look at the meanings of hugging. During my writing process, I use a walking meditation as a Buddhist practice to calm my mind so that I can see my true self and a clearer picture of different layers of the act of hugging. I believe hegemonic gender roles and patriarchy happen everywhere in the world, not particularly in Vietnam. I do not plan to devalue my home country’s cultural values in this paper. This is not the ...


No Woman Is An Island -- Access To Care And Extreme Measures For Cancer Pain And Lymphedema: A Case Report, Lauren M. Hall, Julia Reilly, Mathew J. Most, Jennifer Baima 2019 University of Massachusetts Medical School

No Woman Is An Island -- Access To Care And Extreme Measures For Cancer Pain And Lymphedema: A Case Report, Lauren M. Hall, Julia Reilly, Mathew J. Most, Jennifer Baima

Orthopedics and Physical Rehabilitation Publications and Presentations

Background: Cancer rehabilitation is a rapidly growing diverse field in physiatry. This case provides an example where rehabilitation physiatrists played a crucial role in the pain management, education, and rehabilitation before and after a palliative amputation. Due to her limited resources, both in her home country and in her local community, she could not access appropriate care that may have prevented the need for amputation. Though amputation is not generally accepted as the first line of treatment for pain, there have been several reports of palliative amputation in metastatic cancer patients. In particular, fore quarter amputations have been reported in ...


The Effects Of Medical Cannabis Use Among Adults With Chronic Pain: An Integrative Review Of The Literature, Bridget A. Asevedo 2019 University of Central Florida

The Effects Of Medical Cannabis Use Among Adults With Chronic Pain: An Integrative Review Of The Literature, Bridget A. Asevedo

Honors Undergraduate Theses

The purpose of this integrative literature review was to understand the effects of medical cannabis for chronic pain management in adults. Anecdotal reports suggest the use of medical marijuana as a pain management therapy could be an alternative to opioids and other medications which have long term consequences. Potential uses span the health care continuum, from prescribed outpatient symptom management, to acute care, extended care, home care, and hospice treatment settings. The methodology included a review and synthesis of relevant research articles from 2012 to 2018, written in the English language. The findings suggest medical cannabis has the potential of ...


Art In The Stages Of Suffering And Death, Joanna Aramini 2018 College of the Holy Cross

Art In The Stages Of Suffering And Death, Joanna Aramini

Visual Arts Department Student Scholarship

There has always been a strong link between art and the study of science and medicine, and one of the most iconic images of suffering and death in history to date is Christ suffering on the cross. In this thesis, I examine if and how art can make it possible to transcend human pain and overcome suffering, especially in our modern society where pain is seen as something we cannot deal with, and where we look to medicine and prescriptions to diminish it. I argue that art in the states of suffering and death, closely examining Michelangelo’s La Pieta ...


Impact Of Cigarette Smoking Status On Pain Intensity Among Veterans With And Without Hepatitis C, Shaina M. Lynch, Sarah M. Wilson, Eric C. DeRycke, Mary A. Driscoll, William C. Becker, Joseph L. Goulet, Robert D. Kerns, Kristin M. Mattocks, Cynthia A. Brandt, Harini Bathulapalli, Melissa Skanderson, Sally G. Haskell, Lori A. Bastian 2018 Medical College of Wisconsin

Impact Of Cigarette Smoking Status On Pain Intensity Among Veterans With And Without Hepatitis C, Shaina M. Lynch, Sarah M. Wilson, Eric C. Derycke, Mary A. Driscoll, William C. Becker, Joseph L. Goulet, Robert D. Kerns, Kristin M. Mattocks, Cynthia A. Brandt, Harini Bathulapalli, Melissa Skanderson, Sally G. Haskell, Lori A. Bastian

Population and Quantitative Health Sciences Publications

Objective: Chronic pain is a significant problem in patients living with hepatitis C virus (HCV). Tobacco smoking is an independent risk factor for high pain intensity among veterans. This study aims to examine the independent associations with smoking and HCV on pain intensity, as well as the interaction of smoking and HCV on the association with pain intensity.

Design/Particpants: Cross-sectional analysis of a cohort study of veterans of Operations Enduring Freedom/Iraqi Freedom/New Dawn (OEF/OIF/OND) who had at least one visit to a Veterans Health Administration (VHA) primary care clinic between 2001 and 2014.

Methods: HCV ...


Psychological And Family Variables Associated With The Treatment Of Pediatric Idiopathic Pain, Rachael Hoffman 2018 Duquesne University

Psychological And Family Variables Associated With The Treatment Of Pediatric Idiopathic Pain, Rachael Hoffman

Electronic Theses and Dissertations

The present study examined variability in treatment outcomes of children with idiopathic chronic pain. Specifically, the biopsychosocial model was used as a framework to consider the way that symptoms of depression and anxiety as well as parent response to pain contributed to the change in a child’s confidence in participating in daily activities following treatment in an inpatient chronic pain treatment program.


Exploring The Clinical Utility Of Mobile Applications For Promoting Affect Regulation Among Clients With Behavioral Health Problems, Caroline Fenkel 2018 University of Pennsylvania

Exploring The Clinical Utility Of Mobile Applications For Promoting Affect Regulation Among Clients With Behavioral Health Problems, Caroline Fenkel

Doctorate in Social Work (DSW) Dissertations

Nearly 25 percent of adults in the United States are diagnosed with a behavioral health condition, most commonly depression, anxiety disorders and substance use disorders. Each of these diagnoses is associated with significant disruptions in affect regulation which encompasses the capacity to up and down regulate emotions. Best practice treatment for these conditions includes psychotropic medications combined with individual or group-based psychotherapeutic modalities which regardless of the therapist’s theoretical orientation attempt to promote affect regulation through skill transfer and strategies for observing one’s ability to regulate emotions. Similarly, attention to regulatory capacity is central to many emerging self-help ...


Cognitive And Emotional Correlates Of Improved Gait Distance During The Course Of Physical Therapy Treatment For An Incomplete Spinal Cord Injury, Danielle Miller 2018 Union College

Cognitive And Emotional Correlates Of Improved Gait Distance During The Course Of Physical Therapy Treatment For An Incomplete Spinal Cord Injury, Danielle Miller

Honors Theses

Objective

The focus of spinal cord injury rehabilitation over the past four decades has shifted from medical management to issuses that affect quality of life and community participation (Gómara- Toldrà, Sliwinski, & Dijkers, 2014). However, the care team for spinal cord injury patients still need to collaberate in order to design and implement interventions that result in maximum participation to provide an individual with a spinal cord injury an effective rehabilitation program. In order to create such a rehablitation program, the care team must know how certain psychological and cognitive aspects, such as depression and implict memory, are related to the ...


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