Organosiloxane-Boron Based Liquid Electrolytes For Application In Lithium-Air Batteries, 2018 Clark Atlanta University
Organosiloxane-Boron Based Liquid Electrolytes For Application In Lithium-Air Batteries, Ahmed A. Alzharani
Electronic Theses & Dissertations Collection for Atlanta University & Clark Atlanta University
The synthesis of 2,4,6,8-Tetramethylcyclotetrasiloxane (D4H), and Poly(methylhydrosiloxane) (PMHS) average molecular weight 1700-3200 g/mol, were functionalized with different repeat units of methoxy polyethylene glycol (PEG) (n = 8,12,17). These compounds act as polymer electrolytes with a backbone of siloxane and they were prepared via hydro-silylation reaction to be functionalized with different molecular weights of Ally-PEG. The compounds were confirmed by FT-IR, 1H-NMR and 13C NMR spectroscopy. A hydro-silylation reaction between the functionalized AllyPEG of different molecular weights produced four compounds with a low glass transition temperature that could improve comb like ...
Combination Therapy: Parp Inhibitor Synergizes The Therapeutic Efficacy Of Doxorubicin In The Treatment Of Prostate Cancer, 2018 Pittsburg State University
Combination Therapy: Parp Inhibitor Synergizes The Therapeutic Efficacy Of Doxorubicin In The Treatment Of Prostate Cancer, Momin Ansare
Electronic Thesis Collection
Men are most susceptible to prostate cancer in the United States. The general treatment options include surgery, hormone therapy, chemotherapy, and radiation therapy. But in recent days, the nanoformulation have shown promising applications in overcoming the drawbacks of the currently available treatment options. To complement, we tried to enhance the capability of the nanoparticle formulation by loading them with a novel drug combination for the treatment of prostate cancer. Herein, we synthesized folate conjugated iron oxide nanoparticles encapsulated with doxorubicin and olaparib for imaging and targeted treatment of prostate cancer. Both drugs are approved by FDA for clinical cancer treatment ...
Synthesis Of Doxorubicin-Based Prodrug And Activatable Mr Nanoprobe For The Imaging And Treatment Of Cancer, 2018 Pittsburg State University
Synthesis Of Doxorubicin-Based Prodrug And Activatable Mr Nanoprobe For The Imaging And Treatment Of Cancer, Bayan Dous
Electronic Thesis Collection
Magnetic Resonance Imaging (MRI) is increasingly being used as a diagnostic tool for cancer. We propose a novel molecular probe, Gadolinium-DTPA disulfide-bonded Doxorubicin (Gd-DTPA-SS-Doxo) encapsulated in iron oxide which could provide a dual modality for detecting malignant growth while simultaneously targeting treatment options. We first synthesized Gd-DTPA-SS-Doxo followed by encapsulation within the poly (acrylic acid) (PAA) coating of iron oxide nanoparticle (IONP), producing a nanoprobe (IO-Gd-DTPA-SS-Doxo) with quenched longitudinal spin lattice magnetic relaxation (T1). After receptor-mediated internalization, Gd-DTPA-SS-Doxo is released from the nanoprobe’s polymeric coating due to the acidic microenvironment of the tumor. When the molecular probe is subjected ...
Polyhedral Oligomeric Silsesquioxane-Phosphate Glass Matrix Nanocomposites With Additional Chapter On Phosphate Glass-Poly(Ethylene Terephthalate) Matrix Composites, 2018 The University of Southern Mississippi
Polyhedral Oligomeric Silsesquioxane-Phosphate Glass Matrix Nanocomposites With Additional Chapter On Phosphate Glass-Poly(Ethylene Terephthalate) Matrix Composites, Kyoungtae Kim
Preparation and characterization of tin fluorophosphate glass (Pglass) matrix nanocomposites incorporating polyhedral oligomeric silsesquioxane (POSS) were investigated on the structural, thermal, morphological, mechanical, and rheological properties. Various processes including synthesis, extrusion and sintering processes were applied to prepare the nanocomposite samples. Another application of POSS with hydrophobic functional groups on the well-structured nanoscale silicate cage with three silanol groups was investigated to present the feasibility to use POSS molecule as a coating material on the surface of the hydrophilic inorganic glass. In addition, Poly(ethylene terephthalate) polymer matrix composites incorporating Pglass was studied to present the benefits of the Pglass ...
Influence Of High Aspect Ratio Nanoparticle Filler Addition On Piezoelectric Nanocomposites, 2018 California Polytechnic State University, San Luis Obispo
Influence Of High Aspect Ratio Nanoparticle Filler Addition On Piezoelectric Nanocomposites, Jeremy A. Armas
Master's Theses and Project Reports
Piezoelectric nanogenerators (PNGs) are a new class of energy harvesting materials that show potential as a direct energy source for low powered electronics. Recently, piezoelectric polymers have been utilized for PNG technology due to low toxicity, high flexibility, and facile solution processing which provide manufacturing opportunities such as screen printing. Throughout the last decade, countless projects have focused on how to enhance the energy harvesting capabilities of these PNGs through the incorporation of nanoparticle fillers, which have been reported to enhance the piezoelectric properties of the film either directly through their intrinsic piezoelectric properties or through acting as surfaces for ...
High-Throughput Assessment Of A Novel, Thiol-Acrylate Hydrogel For Tumor Spheroid Synthesis In A Microfluidic Device, 2018 Louisiana State University and Agricultural and Mechanical College
High-Throughput Assessment Of A Novel, Thiol-Acrylate Hydrogel For Tumor Spheroid Synthesis In A Microfluidic Device, Nathan Daniel Kersker
LSU Master's Theses
The extracellular environment plays an important role in regulating cell behavior. The mechanical, structural, and compositional properties of the extracellular matrix can determine the fate of the growing cells. Standard two-dimensional culturing in a flask fails to represent a native cellular environment. To create the native environment suitable for cells, hydrogels were previously studied. One of the most extensively studied synthetic hydrogels was a poly(ethylene glycol diacrylate) (PEGDA) hydrogel. However, the need for UV polymerization may introduce unwanted changes in cell morphology and viability. The hydrogel being proposed was a form of a thiol-acrylate hydrogel that can eliminate this ...
A New Generation Of Functional Polyisobutylenes For Advanced Applications, 2018 The University of Southern Mississippi
A New Generation Of Functional Polyisobutylenes For Advanced Applications, Corey M. Parada
Polyisobutylene (PIB) is a fully saturated, aliphatic polymer of high commercial importance due to its superior gas barrier properties and high chemical/oxidative stability. One commercial end-use for PIB is in insulated glass windows (IGU), where it acts as a gas/moisture barrier and sealant. Under certain adverse conditions, catastrophic failure of the PIB sealant may result in aesthetic and functional failure of the IGU, which necessitates replacement of the unit. Thus, there exists a need to improve current generations of thermoplastic PIB sealants to be able to withstand the harsh environments found in current real-world applications.
In the first ...
Structure-Property Relationships Of Solvent-Cast Organic Thin Films For Model Corrosion Control Coatings, 2018 The University of Southern Mississippi
Structure-Property Relationships Of Solvent-Cast Organic Thin Films For Model Corrosion Control Coatings, Austin Maples
This dissertation aimed at answering several fundamental questions, specifically: 1) What is the effect of scribing parameters on visual corrosion assessments? 2) What role do molecular weight, residual solvent, and polymer composition have on morphological changes in organic thin films? 3) What alternatives to visual assessments could be implemented to better understand and detect corrosion before macroscopic failure? This research definitively proved that scribes can vary in type and dimensions, and yet are still comparable if the scribe dimensions before exposure are known. Furthermore, it demonstrated that solvents common to a variety of coating industries could become trapped within the ...
Effect Of Network Structure On Free Volume And Gas Transport Properties Of Thiol-Ene And Epoxy-Amine Networks, 2018 The University of Southern Mississippi
Effect Of Network Structure On Free Volume And Gas Transport Properties Of Thiol-Ene And Epoxy-Amine Networks, Ramesh Krishnan Ramakrishnan
Network parameters such as cross-link density or intermolecular interactions were used as effective parameters to control polymer chain packing or free volume and thereby control the mass transport properties of networks.
A series of polyethylene glycol (PEG) based thiol-ene elastomeric networks having a broad range of molecular weight between cross-links, Mc, (inverse of cross-link density) was prepared. The specific volume of the networks was studied as a function of temperature and pressure using high pressure dilatometry, and the obtained PVT data was fit using Simha-Somcynsky equation of state (S-S eos) analysis. Fractional free volume, quantified through S-S eos analysis ...
Flexible And Versatile Soft Templates For Mesoporous Silicas And Organosilicas Based On Pluronic Block Copolymer Surfactants And Their Mixtures, 2018 The Graduate Center, City University of New York
Flexible And Versatile Soft Templates For Mesoporous Silicas And Organosilicas Based On Pluronic Block Copolymer Surfactants And Their Mixtures, George Farid
All Dissertations, Theses, and Capstone Projects
In this dissertation, the work will be discussed that was focused on the synthesis of consolidated periodic mesoporous materials such as 2-D hexgonal ordered mesoporous silicas (SBA-15) as well as single-micelle-templated silica and organosilica nanotubes and nanospheres using triblock copolymer surfactants and their mixtures in the presence of a swelling agent. The introductory section, Chapter 1, will address the current state of the tunability of single-micelle-templated silica and organosilica nanotubes and will compare it with the work presented in this dissertation on the use of a dual-surfactant templating systems. Chapter 2 of the dissertation discusses transmission electron microscopy characterization of ...
Plant Stimuli-Responsive Biodegradable Polymers For The Use In Timed Release Fertilizer Coatings, 2018 The University of Western Ontario
Plant Stimuli-Responsive Biodegradable Polymers For The Use In Timed Release Fertilizer Coatings, Spencer Heuchan
Electronic Thesis and Dissertation Repository
The use of nitrogen-based fertilizers continues to accelerate with human population growth and increases in global food requirements. Enhanced efficiency fertilizers (EEFs) have been developed to improve the synchronization between nutrient supply and crop nutrient demand. However, many of the current controlled release fertilizers are coated with non-degradable polymers that contribute to accumulation of microplastics within ecosystems. This thesis describes research towards the development of a new class of fertilizer coatings using a self-immolative polymer known as poly (ethyl glyoxylate) (PEtG). PEtG itself does not have suitable properties to produce a viable coating but once blended with another degradable polyester ...
Biomass Based Monomers For Synthesis Of Renewably Sourced Polymers, 2018 University of Maine
Biomass Based Monomers For Synthesis Of Renewably Sourced Polymers, Anushka E. Vithanage
Electronic Theses and Dissertations
Limited fossil resources have raised research focus on synthesizing novel, sustainable polymers and renewably sourcing existing petroleum based polymers. This work presents the synthesis and ring opening polymerization (ROP) of a new functionalized lactone monomer, methoxy-δ-hexalactone (MDHL), to yield a functionalized polyester (polyMDHL). MDHL can be renewably sourced from hydroxymethylfurfural, a renewable platform chemical. MDHL was synthesized from methyl cyclopentanone-2-carboxylate by a five-step synthesis with a global yield of 23%. ROP of MDHL was conducted with benzyl alcohol initiator, catalyzed by diphenyl phosphate. 1H Nuclear Magnetic Resonance spectroscopy verified polyMDHL chemical structure. Targeting higher molecular weights for polyMDHL by increasing ...
Chemically Cross-Linked Polysaccharide-Based Hydrogels Via Thiol-Norbornene Reaction As Sustainable Biomaterials, Nayereh Dadoo
Electronic Theses and Dissertations
Hydrogels are 3D polymeric networks with high water content and are widely being investigated for biomedical applications such as tissue engineering. Polysaccharides have been used to fabricate hydrogels due to their natural abundance, biocompatibility, and immunogeniety. Additionally, polysaccharide-based hydrogels can provide mechanical and biological cues similar to those of the natural environments. In this work, thiol-norbornene chemistry was used to fabricate polysaccharide-based hydrogels including hyaluronic acid (HA), carboxymethyl cellulose (CMC), and cellulose nanofibrils (CNFs). Hydrogels with tunable physical and mechanical properties were achieved. The properties of these hydrogels were spatiotemporally modified by photopatterning. Also, high stem cell viability was achieved ...
Highly Conductive Solid Polymer Electrolytes: Poly(Ethylene Oxide)/Litfsi Blends, 2018 Clark Atlanta University
Highly Conductive Solid Polymer Electrolytes: Poly(Ethylene Oxide)/Litfsi Blends, Zahra Alquraini
Electronic Theses & Dissertations Collection for Atlanta University & Clark Atlanta University
In this study, highly ionic conductive solid polymer electrolytes have been prepared by blending high molecular weight polyethylene oxide (PEO: MW 35,000 and 100,000) and bis(trifluoromethane)sulfonamide lithium (LiTFSI) salt. The ionic conductivities were determined for several compositions of the blends at different temperatures. A maximum ionic conductivity of 9.45 x 10-6 S cm-1 at 25 °C has been obtained for the blends containing PEO-35,000/LiTFSI at an ethylene oxide to lithium salt ratio (EO/Li+) of 5, whereas a maximum ionic conductivity 7.7 x 10-6 S cm-1 at 25 ...
Thienoisatin Oligomers As N-Type Molecular Semiconductors, 2018 Purdue University
Thienoisatin Oligomers As N-Type Molecular Semiconductors, Natalie M. Kadlubowski, Xuyi Luo, Jianguo Mei
The Summer Undergraduate Research Fellowship (SURF) Symposium
Organic field effect transistors (OFETs) offer many advantages compared to traditional inorganic transistors, such as flexibility and solution processability. In this study we design and synthesize two thienoisatin-based organic semiconducting small molecules, then investigate their electronic properties in n-type OFETs. To introduce n-type charge transport, electron-withdrawing dicarbonitrile moieties were installed on thienoisoindigo and bis-thienoisatin molecules, which led to a quinoidal conjugation on thienoisoindigo, while maintaining an aromatic conjugation on the bis-thienoisatin. Following the syntheses, the molecules were characterized to determine highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) levels via cyclic voltammetry, as well as any potential ...
Applications Of Diels-Alder Chemistry In Polymer Synthesis, 2018 California Polytechnic State University, San Luis Obispo
Applications Of Diels-Alder Chemistry In Polymer Synthesis, Joshua C. Stambaugh, Philip J. Costanzo, Sierra E. Gosting
STAR (STEM Teacher and Researcher) Presentations
Diels-Alder chemistry is utilized for a myriad of commercial applications during polymer synthesis, ranging from self-healing materials to heat responsive materials to emulsion coatings. In particular, the ability to regulate and control the amount and type of functional group linkages is key component for polymer applications. A common strategy that is employed is the use of phenolic maleimide as a dienophile during Diels-Alder synthesis to control the linkages on a polymer, which determines its properties and functionality. This summer was the beginning of a project to prepare a commercial scale, water-based emulsion floor coating/polish. The first step in this ...
Effects Of High Pressure On Photochemical Reactivity Of Organic Molecular Materials Probed By Vibrational Spectroscopy, 2018 The University of Western Ontario
Effects Of High Pressure On Photochemical Reactivity Of Organic Molecular Materials Probed By Vibrational Spectroscopy, Jiwen Guan
Electronic Thesis and Dissertation Repository
Chemical transformations of molecular materials induced by high pressure and light radiation exhibit novel and intriguing aspects that have attracted much attention in recent years. Particularly, under the two stimuli, entire transformations of molecular species can be realized in condensed phases without employing additional chemical constraints, e.g., the need of solvents, catalysts or radical initiators. This new synthetic approach in chemistry therefore satisfies increasing need for production methods with reduced environmental impacts. Motivated by these promises, my Ph. D thesis focuses on this state-of-the-art branch of high-pressure photochemistry. Specifically, high pressure is employed to create the necessary reaction conditions ...
Development Of Mof@Polymer Composite Materials Through Bottom-Up Self-Assembly Techniques, 2018 University of New Mexico
Development Of Mof@Polymer Composite Materials Through Bottom-Up Self-Assembly Techniques, Roberto C. Arbulu
MOF-based mixed matrix membranes (MMMs) are a promising new class of MOF/polymer composite materials. Currently, fabrication of MMMs is based on top-down methods with limited control over MOF positioning, integration, or morphology. This work focuses on the growth of well-defined one-dimensional (1-D) MOF nanostructures within the pores of a nanoporous polymer template, either commercially available or through the self-assembly of block co-polymers having tailor-designed surface functionalities. Studies were conducted using zeolitic imidazole framework-8 (ZIF-8) and polycarbonate track etched (PCTE) membranes, which demonstrated the feasibility of the outlined approach, and revealed the formation of distinct super- and nanostructures with controlled ...
Electrospinning And Electrospraying Of Unsaturated Poly(Macrolatone)S: Alternative Material For Biomedical Applications., 2018 Royal College of Surgeons in Ireland
Electrospinning And Electrospraying Of Unsaturated Poly(Macrolatone)S: Alternative Material For Biomedical Applications., Fernando Cabral Sales De Oliveira
Chapter 1 – Introduction Lactones are a promising class of monomers which enable production of a large number of polymers with different properties. This thesis aims to investigate materials derived from the unsaturated macrolactone globalide and their processing into variable structures by electrospinning and electrospraying. The first chapter provides an overview of the polymerisation techniques, spinning and spraying technology as well as the application of aliphatic polyesters in biomedical applications.
Chapter 2 – Optimization of electrospinning process using poly(globalide). Poly(globalide) (PGl) has not be used in electrospinning to date. In this chapter the spinning conditions were optimised with the goal ...
The Effect Of Soxhlet Extraction And Synthesis Temperature On Properties Of Polyaniline, 2018 Old Dominion University
The Effect Of Soxhlet Extraction And Synthesis Temperature On Properties Of Polyaniline, Samuel Watson Stahl
Chemistry & Biochemistry Theses & Dissertations
Polyaniline was synthesized by the chemical oxidation of aniline in an HCl solution by ammonium persulfate. The temperature of the synthesis was varied to increase the molecular weight of the polymer from 37,600 Da to 52,400 Da. Soxhlet extraction using methanol as the primary solvent was performed on half the sample in order to further increase the average molecular weight by approximately 3150 Da and decrease the polydispersity index by 0.8. Films were cast from 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU) and N-methyl-2-pyrrolidone (NMP) and then doped with trifluoromethanesulfonic acid.
The effect of the ...