Bacillus Cereus And Bacillus Anthracis Germination Kinetics: A Michaelis-Menten Approach, 2010 University of Nevada, Las Vegas
Bacillus Cereus And Bacillus Anthracis Germination Kinetics: A Michaelis-Menten Approach, Helen Luu
UNLV Theses, Dissertations, Professional Papers, and Capstones
Bacillus species are rod-shaped, gram-positive bacteria that are capable of producing endospores. In this dormant stage, the endospores can persist in hostile physical and chemical environments. Once conditions become favorable, the spores germinate into actively dividing cells, vegetative cells. Germination is a crucial step for the pathogenicity of the Bacilli in affecting a host organism.
Our study applies mathematical approaches to spore germination to determine whether the binding of one germinant will affect the binding of another germinant. We pursued this approach with two different species, B. cereus and B. anthracis, both pathogenic organisms. B. cereus is a widely known ...
The In-Situ Removal Of Menthofuran From Peppermint Oil And Subsequent Reactions Of The Solid-Supported Adduct, 2010 Western Michigan University
The In-Situ Removal Of Menthofuran From Peppermint Oil And Subsequent Reactions Of The Solid-Supported Adduct, Robert Joseph Justice Ii
Menthofuran is an aromatic heterocyclic compound found naturally in the essential oil of Mentha piperita L. or peppermint. Natural peppermint oil may contain between approximately 2 to 8% menthofuran.
Peppermint oil is a complex mixture of over 350 identified chemical compounds; market demands dictate the extent of processing the oil undergoes prior to being introduced into consumer goods. Menthofuran has long been known to readily autoxidize, either alone or within the peppermint oil matrix, leading to a discolored oil with negative organoleptic consequences that adversely affects its commercial viability. Therefore, a facile method for selective removal of menthofuran was developed ...
New Chiral Phosphoramidite Complexes Of Iron As Catalytic Precursors In The Oxidation Of Activated Methylene Groups, 2010 University of Missouri–St. Louis
New Chiral Phosphoramidite Complexes Of Iron As Catalytic Precursors In The Oxidation Of Activated Methylene Groups, Pushkar Shejwalkar, Nigam P. Rath, Eike B. Bauer
Computational Protein Design: Advances In The Design And Redesign Of Biomolecular Nanostructures, 2010 University of Pennsylvania
Computational Protein Design: Advances In The Design And Redesign Of Biomolecular Nanostructures, Jeffery G. Saven
Departmental Papers (Chemistry)
Computational protein design facilitates the continued development of methods for the design of biomolecular structure, sequence and function. Recent applications include the design of novel protein sequences and structures, proteins incorporating nonbiological components, protein assemblies, soluble variants of membrane proteins, and proteins that modulate membrane function.
Ion-Neutral Chemistry Of Importance To Astrophysical And Cosmological Environments, 2010 University of Colorado, Boulder
Ion-Neutral Chemistry Of Importance To Astrophysical And Cosmological Environments, Oscar Martinez Jr.
Chemistry & Biochemistry Graduate Theses & Dissertations (1986-2018)
Scientific studies have led to a more thorough understanding of processes directing the evolution of the Universe. In addition to observational studies with telescopes, terrestrial laboratory studies now contribute to the knowledge encompassed by astronomy and astrophysics. The laboratory-astrophysics experiments performed for this thesis focused on topics ranging from the birth of the first stars and galaxies to chemical processes important to the interstellar medium (ISM).
Models attempt to derive a better understanding of certain cosmological and astrophysical environments. Their reliability, however, depends heavily on the accuracy of data employed. Our contributions to laboratory astrophysics are based on the use ...
The Development Of An Effective Water-Soluble Receptor For Pyrene Derivative Dyes, 2010 Lynchburg College
The Development Of An Effective Water-Soluble Receptor For Pyrene Derivative Dyes, Ashley Longstreet
Undergraduate Theses and Capstone Projects
A receptor with enhanced water solubility was synthesized from an existing receptor to be used as a pyranine fluorescence quencher in endovesiculation detection assays. The existing receptor consisted of a cyclen core with four protruding arms containing an aryl nitro group at each end. Its poor water solubility limited the accuracy and precision of the endovesiculation assay because the low concentration of receptor did not match the concentration of pyranine. To increase the water solubility, ethoxy groups were attached to the ends of each arm by first selectively reducing the nitro group to an amine with NaBHU4, H2, and a ...
Functionalization Of Aromatic Organic Molecules By Anhydrous Flourides And By Reductive Elimination Of Iodine(Iii), 2010 University of Nebraska - Lincoln
Functionalization Of Aromatic Organic Molecules By Anhydrous Flourides And By Reductive Elimination Of Iodine(Iii), Bijia Wang
Student Research Projects, Dissertations, and Theses - Chemistry Department
Solution phase reactivity of nucleophilic fluoride reagents is attenuated by ion-pairing interactions. 1H-19F HOESY competition experiments permit generation of a fluoride ion affinity scale in the weak-binding regime. Direct DFT calculations of ion pair interaction energies as well as calculated cation electrostatic potential maps can be used to predict solution phase ion pairing tendencies for closely related ammonium cations. It was found by studying the decomposition of tetra-substituted ammonium cations by fluoride that: 1) rates of E2 decomposition is faster than the SN2 pathway; 2) aryl substituents destabilize the cations; 3) steric strain tends to ...
Relatin Dissolved Oxygen Concentration To Fish Distribution In Jarecki Lake, 2010 University of Nebraska at Lincoln
Relatin Dissolved Oxygen Concentration To Fish Distribution In Jarecki Lake, Adam Sutton
Environmental Studies Undergraduate Student Theses
Abstract Water temperature and dissolved oxygen (DO) profiles were measured once every month from mid July to mid February in a relatively deep sand-pit lake in southeast Nebraska. These profiles showed depleted DO concentrations below the thermocline during summer stratification indicating areas fish will likely avoid in summer months. Colder temperatures in fall caused complete mixing of the water column allowing fish to inhabit all depths of the lake. An inverse temperature stratification occurred directly below the ice during winter months as ice cover cooled the surface water to below 4 degrees Celsius. Ice cover also blocked air – water oxygen ...
Herbicides And Amphibian Populations, 2010 University of Nebraska - Lincoln
Herbicides And Amphibian Populations, Zach Shirk
Environmental Studies Undergraduate Student Theses
Amphibians are a unique class of species that are found worldwide except Antarctica and Greenland. They range in size from a few millimeters to over six feet long. Amphibian’s habitats are as various as their size, but one thing in common is that amphibians require an aquatic location to breed. Amphibians live in deserts, mountain prairies, rain forest, wetlands, and almost everywhere in between. Amphibians are an integrated part of most natural ecosystems across the world. Amphibians are a critical part of many food chains; they provide the important link between secondary and tertiary consumers. Amphibians are indicator species ...
Synthesis Of Cifidabco And Mannose Co-Functionalized G(4)-Pamam Dendrimer For Use In Antibiotics, 2010 Carroll College, Helena, MT
Synthesis Of Cifidabco And Mannose Co-Functionalized G(4)-Pamam Dendrimer For Use In Antibiotics, Harrison Vankoten
Chemistry and Physics Undergraduate Theses
Synthesis of C16DABCO and mannose co-functionalized G(4)-PAMAM dendrimer is expected to yield a useful antimicrobial that is effective in binding to mannose specific lectins on bacterial fimbriae. Thus far, mannose has been attached to the dendrimer with near complete functionalization. C16DABCO and mannose cofunctionalized G(4)-PAMAM dendrimer have been synthesized, but not in sufficient quantities to allow examination of its the antibacterial properties. Future work includes optimizing the final synthesis and performing toxicity studies.
Computational Design And Elaboration Of A De Novo Heterotetrameric Α-Helical Protein That Selectively Binds An Emissive Abiological (Porphinato)Zinc Chromophore, H Christopher Fry, Andreas Lehmann, Jeffery G. Saven, William F. Degrado, Michael J. Therien
Departmental Papers (Chemistry)
The first example of a computationally de novo designed protein that binds an emissive abiological chromophore is presented, in which a sophisticated level of cofactor discrimination is pre-engineered. This heterotetrameric, C(2)-symmetric bundle, A(His):B(Thr), uniquely binds (5,15-di[(4-carboxymethyleneoxy)phenyl]porphinato)zinc [(DPP)Zn] via histidine coordination and complementary noncovalent interactions. The A(2)B(2) heterotetrameric protein reflects ligand-directed elements of both positive and negative design, including hydrogen bonds to second-shell ligands. Experimental support for the appropriate formulation of [(DPP)Zn:A(His):B(Thr)](2) is provided by UV/visible and circular dichroism spectroscopies ...
Bismuth(Iii) Bromide In Organic Synthesis. A Catalytic Method For The Allylation Of Tetrahydrofuranyl And Tetrahydropyranyl Ethers, 2010 Illinois Wesleyan University
Bismuth(Iii) Bromide In Organic Synthesis. A Catalytic Method For The Allylation Of Tetrahydrofuranyl And Tetrahydropyranyl Ethers, Ram Mohan, Scott Krabbe, Veronica Angeles
A bismuth bromide-catalyzed (10.0 mol %) multicomponent reaction involving the allylation of THF- and THP-ethers, followed by in situ derivatization with acetic anhydride to generate highly functionalized esters has been developed under solvent-free conditions. To the best of our knowledge, this is the first report of a catalytic procedure for the allylation of THF- and THP-ethers to yield ring-opened products.
2-(3-Nitrophenoxy)Quinoxaline, 2010 University of Malaya
2-(3-Nitrophenoxy)Quinoxaline, Hairul Anuar Bin Tajuddin
Hairul Anuar Bin Tajuddin
In the title molecule, C(14)H(9)N(3)O(3), the dihedral angle between the quinoxaline and benzene rings is 77.13 (9)degrees. The molecule is twisted about the ether-benzene O-C bond, with a C-O-C-C torsion angle of -102.8 (2)degrees. In the crystal, molecules are linked by C-H center dot center dot center dot O hydrogen bonds, forming layers in the ab plane, with one nitro O atom accepting two such interactions. The layers stack along the c-axis direction via weak C-H center dot center dot center dot pi interactions.
A Mild And Chemoselective Method For The Deprotection Of Tert-Butyldimethylsilyl (Tbdms) Ethers Using Iron(Iii) Tosylate As A Catalyst, 2010 Illinois Wesleyan University
A Mild And Chemoselective Method For The Deprotection Of Tert-Butyldimethylsilyl (Tbdms) Ethers Using Iron(Iii) Tosylate As A Catalyst, Ram Mohan, Jason Bothwell, Veronica Angeles, James Carolan, Margaret Olson
The most common method for the deprotection ofTBDMS ethers utilizes stoichiometric amounts of tetrabutylammonium fluoride, n-Bu4N+F(TBAF), which is highly corrosive and toxic. We have developed a mild and chemoselective method for the deprotection ofTBDMS, TES, and TIPS ethers using iron(III) tosylate as a catalyst. Phenolic TBDMS ethers, TBDPS ethers and the BOC group are not affected under these conditions. Iron(III) tosylate is an inexpensive, commercially available, and non-corrosive reagent.
Iron(Iii) Tosylate-Catalyzed Deprotection Of Aromatic Acetals In Water, 2010 Illinois Wesleyan University
Iron(Iii) Tosylate-Catalyzed Deprotection Of Aromatic Acetals In Water, Ram Mohan, Margaret Olson, James Carolan, Michael Chiodo, Phillip Lazzara
The deprotection of aromatic as well as conjugated acetals and ketals in water is catalyzed by iron(III) tosylate (1.0–5.0 mol %). Iron(III) tosylate is an inexpensive and readily available catalyst. The use of water, the most environmentally benign solvent, makes this procedure especially attractive for acetal deprotection.
In Your Element: Green Bismuth, 2010 Illinois Wesleyan University
In Your Element: Green Bismuth, Ram Mohan
No abstract provided.
Development And Applications Of Thioacids In Peptide Chemistry And Exploration Of Methods Toward The Stereochemical Elucidation And Synthesis Of Virgineone, Kasinath Sana
Wayne State University Dissertations
DEVELOPMENT AND APPLICATIONS OF THIOACIDS IN PEPTIDE CHEMISTRY AND EXPLORATION OF METHODS TOWARD THE STEREOCHEMICAL ELUCIDATION AND SYNTHESIS OF VIRGINEONE
Advisor: David Crich
Degree: Doctor of Philosophy
This dissertation describes investigations toward the development of methods for the synthesis of peptidyl thioacids and thioesters, with particular emphasis on applications in peptide chemistry, and the exploration of methods toward the assignment of the relative and absolute configuration of virgineone and its total synthesis.
The first part of chapter one introduces the general characteristics and reactivity of thioacids, and describes their potential for application ...
Technology For The Organic Chemist: Three Exploratory Modules, 2010 Butler University
Technology For The Organic Chemist: Three Exploratory Modules, John J. Esteb, Luanne M. Mcnulty, John Magers, Paul Morgan
Scholarship and Professional Work - LAS
The ability to use computer-based technology is an essential skill set for students majoring in chemistry. This exercise details the introduction of appropriate uses for this technology in the organic chemistry series. The incorporation of chemically appropriate online resources (module 1), scientific databases (module 2), and the use of a chemical drawing program (module 3) are detailed here.
Structure-Reactivity Relationships Of L-Proline Derived Spirolactams And A-Methyl Prolinamide Organocatalysts In The Asymmetric Michael Addition Reaction Of Aldehydes To Nitroolefins., 2010 Institute of Technology, Tallaght
Structure-Reactivity Relationships Of L-Proline Derived Spirolactams And A-Methyl Prolinamide Organocatalysts In The Asymmetric Michael Addition Reaction Of Aldehydes To Nitroolefins., Fintan Kelleher, Sinead Kelly, John Watts, Vickie Mckee
L-Proline derived spirolactams and a-methyl prolinamides act as organocatalysts for the asymmetric conjugate addition of aldehydes to nitroolefins in excellent yields, with good diastereoselectivity and enantioselectivity. Furthermore, low catalyst loadings (5 mol%) and a low aldehyde molar excess (1.5 molar equivalents) were achieved.
Effluent Organic Nitrogen (Eon): Bioavailability And Photochemical And Salinity-Mediated Release, 2010 Old Dominion University
Effluent Organic Nitrogen (Eon): Bioavailability And Photochemical And Salinity-Mediated Release, Deborah A. Bronk, Quinn N. Roberts, Marta P. Sanderson, Elizabeth A. Canuel, Patrick G. Hatcher, Rajaa Mesfioui, Katherine C. Filippino, Margaret R. Mulholland, Nancy G. Love
Chemistry & Biochemistry Faculty Publications
The goal of this study was to investigate three potential ways that the soluble organic nitrogen (N) fraction of wastewater treatment plant (WWTP) effluents, termed effluent organic N (EON), could contribute to coastal eutrophication - direct biological removal, photochemical release of labile compounds, and salinity-mediated release of ammonium (NH4+). Effluents from two WWTPs were used in the experiments. For the bioassays, EON was added to water from four salinities (∼0 to 30) collected from the James River (VA) in August 2008, and then concentrations of N and phosphorus compounds were measured periodically over 48 h. Bioassay results, based on changes ...