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Digestive, Oral, and Skin Physiology Commons

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All Articles in Digestive, Oral, and Skin Physiology

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Using Shared Decision Making And Team-Based Care To Overcome Socioeconomic And Cultural Barriers To Colorectal Cancer Screenings, Amanda Powell, Debra Pyle, Kristin Rowse, Misty Weeman, Rachel Kidder, Internal Medicine/Pediatric Clinic, Ruth Hanselman, Suneela Nayak, Stephen Tyzik, Amy Sparks 2019 Maine Medical Center

Using Shared Decision Making And Team-Based Care To Overcome Socioeconomic And Cultural Barriers To Colorectal Cancer Screenings, Amanda Powell, Debra Pyle, Kristin Rowse, Misty Weeman, Rachel Kidder, Internal Medicine/Pediatric Clinic, Ruth Hanselman, Suneela Nayak, Stephen Tyzik, Amy Sparks

Operational Excellence

Colorectal cancer is the third leading cause of cancer death in the United States. It disproportionally affects minorities and those in lower socioeconomic groups. The use of fecal immunochemical testing (FIT) is a low barrier, low cost and low risk screening tool as compared to the traditional colonoscopy exam. The use of FIT offers the opportunity to overcome barriers such as cultural, economic and low health literacy.

As part of a large health care system, an internal medicine clinic wanted to increase the use and return of FIT in their clinic patients. A team developed a plan for implementing improvement ...


A Provider-Driven Approach To Preventative Oral Care In Nursing Home Facilities, Molly Anderson, Brandon McCrossin, Kary Franchetti, Ruth Hanselman, Suneela Nayak, Stephen Tyzik, Amy Sparks 2019 Maine Medical Center

A Provider-Driven Approach To Preventative Oral Care In Nursing Home Facilities, Molly Anderson, Brandon Mccrossin, Kary Franchetti, Ruth Hanselman, Suneela Nayak, Stephen Tyzik, Amy Sparks

Operational Excellence

Oral care is an essential part of preventative medicine as it minimizes risk for pneumonias and other infections. In nursing home settings, often oral health care is not routinely provided due to a number of issues. A health care system that either owns or contracts nursing home facilities initiated a performance improvement plan to address this patient care concern.

The first goal of this project was to reduce the variation in oral care between nursing home facilities within the system. The second goal was 100% of their patients will have one oral health care exam documented in EPIC once a ...


A Rare Manifestation Of A Bleeding Tubulovillous Duodenal Polyp Presenting As An Upper Gastrointestinal Hemorrhage, Neethi Dasu, Yaser Khalid, Herman Suga, Michael Itidiare, Richard Walters 2019 Rowan University

A Rare Manifestation Of A Bleeding Tubulovillous Duodenal Polyp Presenting As An Upper Gastrointestinal Hemorrhage, Neethi Dasu, Yaser Khalid, Herman Suga, Michael Itidiare, Richard Walters

Stratford Campus Research Day

• Duodenal polyps are a group of polyps that are fairly uncommon to find on endoscopic evaluation (1).

• They are histologically classified according to mucin phenotype into intestinal and gastric subtypes; the intestinal-type polyps are morphologically subdivided into tubular and tubulovillous adenomas (2)

• We present a case of a 76-year-old male with recurrent hematemesis who was found to have an intestinal-type pedunculated tubulovillous adenoma (TVA) in the descending duodenum • An isolated occurrence of non-ampullary sporadic duodenal adenomas (SDA)’s are a rare finding and presentation as an upper GI hemorrhage is extremely uncommon (3)

• Furthermore, our patient’s polyp was pedunculated ...


Xerostomia: A Comprehensive Review, Danevin Putrus 2019 Wayne State University

Xerostomia: A Comprehensive Review, Danevin Putrus

Honors College Theses

This thesis will be highlighting the condition known as Xerostomia. Xerostomia is the condition also known as “dry mouth”. This condition affects many people all throughout the world with symptoms causing bad breath, discomfort, difficulty speaking and many other. The seriousness of this condition can lead to cardiovascular disease, dementia, respiratory infections, diabetes mellitus, rheumatoid arthritis, and even cancer (Absolutedental.com). Currently there is not any one specific solution for the condition although many have been proposed. Throughout the thesis I will closely examine former research studies, current solutions proposed, and propose my own study and solution based on research ...


Microbiota Signatures In Type-2 Diabetic Patients With Chronic Kidney Disease - A Pilot Study, Gratiela P. Gradisteanu, Roxana A. Stoica, Laura Petcu, Ariana Picu, Adrian P. Suceveanu, Teodor Salmen, Diana S. Stefan, Cristian Serafinceanu, Mariana Carmen Chifiriuc, Anca P. Stoian 2019 The Research Institute of the University of Bucharest (ICUB), Bucharest, Romania

Microbiota Signatures In Type-2 Diabetic Patients With Chronic Kidney Disease - A Pilot Study, Gratiela P. Gradisteanu, Roxana A. Stoica, Laura Petcu, Ariana Picu, Adrian P. Suceveanu, Teodor Salmen, Diana S. Stefan, Cristian Serafinceanu, Mariana Carmen Chifiriuc, Anca P. Stoian

Journal of Mind and Medical Sciences

The human microbiota is paramount for normal host physiology. Altered host-microbiome interactions are part of the pathogenesis of numerous common ailments. Currently, much emphasis is placed on the involvement of the microbiome in the pathogenesis of type-2 diabetes mellitus (T2DM), impaired glucose tolerance, and other metabolic disorders (i.e. obesity). Several studies found highly significant correlations of specific intestinal bacteria with T2DM. A better understanding of the role of the microbiome in diabetes and its complications might provide new insights in the development of new therapeutic principles.

Our pilot study investigates the microbiota patterns in Romanian type-2 diabetic patients with ...


Photodynamic Therapy As A New Therapeutic Approach Of Oral Lichen Planus, Sandra Milena Tocut, Madalina Irina Mitran, Cristina Iulia Mitran, Mircea Tampa, Maria Isabela Sarbu, Gabriela Loredana Popa, Simona Roxana Georgescu 2019 Wolfson Medical Center, 61 Halochamim Street, 58100, Holon, Israel

Photodynamic Therapy As A New Therapeutic Approach Of Oral Lichen Planus, Sandra Milena Tocut, Madalina Irina Mitran, Cristina Iulia Mitran, Mircea Tampa, Maria Isabela Sarbu, Gabriela Loredana Popa, Simona Roxana Georgescu

Journal of Mind and Medical Sciences

Oral lichen planus (OLP) is a chronic, immunologically mediated disease, defined by periods of exacerbation and quiescence. The disease is associated with a low mortality risk, but in some instances, morbidity can be important, especially in extensive, erosive forms, with a significant impact on the quality of life. OLP is a chronic T-cell mediated inflammatory disease involving the oral cavity, the most common lesions being located on the oral mucosa, tongue and gums. Its etiology remains in part unknown, but several factors proved to be involved in the development of the disease (drugs, dental materials, infectious agents, psychological factors, autoimmunity ...


Nutritional Management Of Pediatric Patients With Short Bowel Syndrome, Melissa Henry 2019 Kent State University

Nutritional Management Of Pediatric Patients With Short Bowel Syndrome, Melissa Henry

Undergraduate Research Symposium

Short Bowel Syndrome (SBS) and associated nutritional deficiencies result from massive bowel resection. The most common causes of SBS are necrotizing enterocolitis and intestinal atresia, but the condition may be caused by any condition that results in necrotic bowel tissue. Significant research exists regarding the nutritional management of these patients in the immediate post-operative period via total parenteral nutrition and regarding the transition to enteral nutrition for short-term management. Other nutritional and psychological research shows that oral feeding should be the long-term goal for these patients due to the psychological and social benefits of oral feeding. In the long-term management ...


The Pharmabiotic For Phenylketonuria: Development Of A Novel Therapeutic, Chloé Elizabeth LeBegue 2019 University of South Carolina

The Pharmabiotic For Phenylketonuria: Development Of A Novel Therapeutic, Chloé Elizabeth Lebegue

Senior Theses

Phenylketonuria, now known as phenylalanine hydroxylase (PAH) deficiency, is a genetic disorder of metabolism affecting approximately one in every 15,000 infants born in the United States. Patients have nonfunctional PAH enzyme secondary to one or more genetic mutations. The enzyme deficit results in destructive supraphysiologic blood phenylalanine levels upon consumption of the essential dietary amino acid phenylalanine. Current standards of care mitigate signs and symptoms of the disorder, but do not approach a cure. The methods for creating a prototype pharmabiotic as an innovative treatment strategy for PAH deficiency are described herein.

DNA molecular cloning techniques were utilized to ...


Naktide Targeted To Adipocytes Ameliorates Western Diet Induced Obesity, Rebecca D. Pratt 2019 Marshall University

Naktide Targeted To Adipocytes Ameliorates Western Diet Induced Obesity, Rebecca D. Pratt

Theses, Dissertations and Capstones

Obesity has become a worldwide epidemic and is a major risk factor for metabolic syndrome. It is believed that cellular oxidant stress plays a key role in both the development and maintenance of obesity as well as its associated comorbidities such as diabetes, cardiovascular disease, and nonalcoholic steatohepatitis (NASH). We have previously reported that systemic administration of pNaKtide, which targets the Na/K-ATPase oxidant amplification loop was able to decrease oxidative stress and adiposity in mice fed a high fat and fructose supplemented western diet (WD). As adipocytes are believed to play an active role in the development of obesity ...


Session 3 Discussion: The Microstructure Of Eating, Cordelia Running, Bryony James, James Hollis, Kelly Higgins 2018 Purdue University

Session 3 Discussion: The Microstructure Of Eating, Cordelia Running, Bryony James, James Hollis, Kelly Higgins

Food Science and Human Nutrition Publications

The Microstructure of Eating.


Dietary Habits And Lifestyle In School-Aged Children From Bucharest, Romania, Anca Pantea Stoian, Liliana F. Andronache, Razvan Hainarosie, Dan N. Paduraru, Cristinel D. Badiu, Andreea Arsene, Claudia Mehedintu, Georgiana Ditu, Silviu M. Pituru, Cristina Orlov, Mihaela Oros, Cornelia Nitipir 2018 Carol Davila University of Medicine and Pharmacy, Department of Diabetes, Nutrition and Metabolic Disease

Dietary Habits And Lifestyle In School-Aged Children From Bucharest, Romania, Anca Pantea Stoian, Liliana F. Andronache, Razvan Hainarosie, Dan N. Paduraru, Cristinel D. Badiu, Andreea Arsene, Claudia Mehedintu, Georgiana Ditu, Silviu M. Pituru, Cristina Orlov, Mihaela Oros, Cornelia Nitipir

Journal of Mind and Medical Sciences

Background. This study evaluated the difference between boys and girls in terms of nutritional status, lifestyle, and dietary habits during school life.

Materials and Methods. A descriptive and observational study was conducted in 2016, in which 251 children, aged 7-17, from 3 elementary schools and a high school inBucharest,Romania, were evaluated. A questionnaire was used to assess food behavior, eating, and lifestyle habits.

Results. Boys had a significantly higher waist circumference (71.18±9) than girls (67.46±9.91) (p=0.004). Thus 27% of boys were overweight or obese compared with only 22% of the girls. Differences ...


Development Of A Self-Care Questionnaire For Clinical Assessment Of Self-Care In Patients With Inflammatory Bowel Disease: A Psychometric Evaluation, Loven Wickman, Henrik Hjortswang, Marika Wenemark, Henrik Stjernman, Gunilla H. Frisman, Barbara Riegel, Pia Yngman-Uhlin 2018 University of Pennsylvania

Development Of A Self-Care Questionnaire For Clinical Assessment Of Self-Care In Patients With Inflammatory Bowel Disease: A Psychometric Evaluation, Loven Wickman, Henrik Hjortswang, Marika Wenemark, Henrik Stjernman, Gunilla H. Frisman, Barbara Riegel, Pia Yngman-Uhlin

School of Nursing Departmental Papers

Background: Patients with inflammatory bowel disease have lifelong needs to learn how to manage their symptoms and life situation. The range of actions that patients take in order to manage daily life and maintain health is referred to as self-care. Assessment of self-care inpatients with inflammatory bowel disease could allow targeted support and education by health care professionals.There are no existing measures assessing self-care in patients with inflammatory bowel disease.

Objectives: The aim was to develop and evaluate the self-care questionnaire for assessment of self-care among patients with inflammatory bowel disease.

Methods: Qualitative and quantitative methods were used to ...


Understanding The Role Of Phosphoinositide 3-Kinase And Its Function As A Driving Force Behind The Er Stress Response In Fibrostenotic Crohn’S Disease-Affected Ileal Smooth Muscle Cells, Prashant Yadav 2018 Virginia Commonwealth University

Understanding The Role Of Phosphoinositide 3-Kinase And Its Function As A Driving Force Behind The Er Stress Response In Fibrostenotic Crohn’S Disease-Affected Ileal Smooth Muscle Cells, Prashant Yadav

Theses and Dissertations

Crohn’s disease (CD) affects about 780,000 people in the United States alone, and it is estimated that 6-15 per 100,000 persons will receive a diagnosis of this disease each year. There currently is no cure for Crohn’s disease, and available medical therapies simply serve to alleviate the inflammation. This does not help treat fibrostenosis that Crohn’s disease patients may develop, which can only be treated surgically. Finding alternatives to treat CD requires an understanding of mechanisms at the biochemical level. In this thesis, we attempted to gain a better understanding of certain pathways found to ...


Problems In Embalming: Cyanide Poisoning, Rebecca Majus 2017 Southern Illinois University Carbondale

Problems In Embalming: Cyanide Poisoning, Rebecca Majus

ASA Multidisciplinary Research Symposium

To inform funeral professionals, or anyone interested, what cyanide poisoning is, how death from it occurs, how to detect it in postmortem remains, how it poses a problem for embalmers, and what embalming techniques can be used to treat it.


Numerical Simulation Of Heat Stress In Chemical Protective Clothing, Jie Yang, Guowen Song, Liwen Wang, Yun Su, Chunhui Xiang 2017 Donghua University

Numerical Simulation Of Heat Stress In Chemical Protective Clothing, Jie Yang, Guowen Song, Liwen Wang, Yun Su, Chunhui Xiang

Apparel, Events and Hospitality Management Publications

The aim of the paper is to predict heat stress of human wearing chemical protective clothing (CPC). A proposed human thermal model was applied to simulate the core and skin temperatures with inputs of human activity level, clothing properties, and environmental conditions. Manikin tests were conducted to measure the thermal insulation and evaporative resistance of clothing which were two important inputs of the thermal model. The core temperature was predicted as an indicator of heat stress to evaluate the maximum exposure time. The effects of ambient temperature, relative humidity, and metabolic rate on core temperature, skin temperature, and maximum exposure ...


Herpes Simplex Proctitis Mimicking Inflammatory Bowel Disease In A Teenaged Male, Kristen E Sandgren, Nathan B Price, Warren P Bishop, Patrick J McCarthy 2017 University of Iowa

Herpes Simplex Proctitis Mimicking Inflammatory Bowel Disease In A Teenaged Male, Kristen E Sandgren, Nathan B Price, Warren P Bishop, Patrick J Mccarthy

Stead Family Department of Pediatrics Publications

We report the case of a 17-year-old male who was initially assessed for pain with defecation, bloody rectal discharge, and diarrhea, consistent with proctitis. Though proctitis is most commonly due to inflammatory bowel disease (IBD), infectious etiologies must also be considered, including sexually transmitted causes of infectious proctitis. In discussion of his sexual history, he identified as homosexual and acknowledged engaging in receptive anal intercourse. Rectal biopsies obtained via colonoscopy were culture-positive for herpes simplex virus (HSV), leading to a diagnosis of HSV proctitis and treatment with an appropriate antiviral medication. HSV proctitis is more common in individuals with high-risk ...


Feeding Your Microbiome Well, Terry L. Wahls 2017 Dept. of Veteran Affairs; University of Iowa, Iowa City, IA, USA

Feeding Your Microbiome Well, Terry L. Wahls

Journal of Evolution and Health

No abstract provided.


Dietary Refinement And The Upper Gut Microbiota: The Starting Point For Obesity And Non-Communicable Diseases?, Ian Spreadbury 2017 Ancestral Health Society

Dietary Refinement And The Upper Gut Microbiota: The Starting Point For Obesity And Non-Communicable Diseases?, Ian Spreadbury

Journal of Evolution and Health

No abstract provided.


The Host Microbiome Regulates And Maintains Human Health: A Primer And Perspective For Non-Microbiologists, Sunil Thomas, Jacques Izard, Emily Walsh, Kristen Batich, Pakawat Chongsathidkiet, Gerard Clarke, David A. Sela, Alexander J. Muller, James M. Mullin, Korin Albert, John P. Gilligan, Katherine DiGuilio, Rima Dilbarova, Walker Alexander, George P. Prendergast 2017 Lankenau Institute for Medical Research, Wynnewood, Pennsylvania

The Host Microbiome Regulates And Maintains Human Health: A Primer And Perspective For Non-Microbiologists, Sunil Thomas, Jacques Izard, Emily Walsh, Kristen Batich, Pakawat Chongsathidkiet, Gerard Clarke, David A. Sela, Alexander J. Muller, James M. Mullin, Korin Albert, John P. Gilligan, Katherine Diguilio, Rima Dilbarova, Walker Alexander, George P. Prendergast

Faculty Publications in Food Science and Technology

Humans consider themselves discrete autonomous organisms, but recent research is rapidly strengthening the appreciation that associated microorganisms make essential contributions to human health and well being. Each person is inhabited and also surrounded by his/her own signature microbial cloud. A low diversity of microorganisms is associated with a plethora of diseases, including allergy, diabetes, obesity, arthritis, inflammatory bowel diseases, and even neuropsychiatric disorders. Thus, an interaction of microorganisms with the host immune system is required for a healthy body. Exposure to microorganisms from the moment we are born and appropriate microbiome assembly during childhood are essential for establishing an ...


Addressing The Decline In The Uptake Of The Iowa Maternal And Prenatal Screening Program, Sandra Daack-Hirsch, Jane Pendergast, Elizabeth Momany, Timothy Ginader, Andrew Emile Ghattas, Stephanie Stewart, Stanley Grant 2017 University of Iowa

Addressing The Decline In The Uptake Of The Iowa Maternal And Prenatal Screening Program, Sandra Daack-Hirsch, Jane Pendergast, Elizabeth Momany, Timothy Ginader, Andrew Emile Ghattas, Stephanie Stewart, Stanley Grant

Health Policy

Noncommunicable chronic diseases (NCDs) account for almost 90% of total deaths in the United States. The four most common NCDs—cardiovascular diseases, diabetes, cancers, and chronic respiratory diseases—share common risk factors, including tobacco and alcohol use and dietary behaviors associated with obesity and elevated blood sugar. The most common oral diseases— dental caries, periodontal disease, and oral cancer—share these common risk factors. A coordinated approach to primary prevention, the “common risk factor approach,” argues that coordinated primary prevention of oral and systemic diseases will reduce programmatic costs and increase efficiency and effectiveness. However, use of this coordinated approach ...


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