In-Vitro Comparative Evaluation Of The Physical Properties Of Three Dimensional-Printed And Milled High Performance Ceramics, 2019 University of Pennsylvania
In-Vitro Comparative Evaluation Of The Physical Properties Of Three Dimensional-Printed And Milled High Performance Ceramics, Laura Torrecillas-Martinez
Aim: to investigate the potential role of 3D printing to produce zirconia
restorations and to assess the mechanical properties of the 3D printed zirconia.
Hypotheses: 1) The flexural strength of 3D printed yttria-stabilized zirconia is comparable or superior to milled yttria-stabilized, isostatic pressed zirconia, and 2) thermocycling and chewing simulation does not affect the flexural strength of 3D printed yttria-stabilized zirconia.
Material and methods: 30 bars of printed yttria-stabilized zirconia and 10 bars of milled yttria-stabilized, isostatic pressed zirconia were utilized in this study. Printed zirconia bars were divided in 3 groups (10 bars per group): untreated, thermocycling and chewing ...
The Role 18f-Fdg And 18f-Naf Pet/Ct In Assessment Of Temporomandibular Joint Metabolic Activity In Rheumatoid Arthritis, 2019 University of Pennsylvania School of Dental Medicine
The Role 18f-Fdg And 18f-Naf Pet/Ct In Assessment Of Temporomandibular Joint Metabolic Activity In Rheumatoid Arthritis, Abdulrahman A. Aseri
Objective: The aim of this study was to evaluate the efficacy of 18F-fluorodeoxyglucose (FDG) and 18F-sodium fluoride (NaF)PET/CT for assessing the status of the temporomandibular joint (TMJ) of rheumatoid arthritis (RA) patients compared with healthy (non-RA) individuals.
Eighteen patients diagnosed with RA (mean age 55±12.1years: 4 females and 14 males) were included in the test group. Eighteen age-, sex- and race-matched healthy control subjects were selected from the CAMONA clinical trial. PET/CT images were acquired 180-minute post-intravenous administration of FDG and NaF (2.2 MBq/kg). For FDG analysis, regions of interest ...
The Impact Of Cleft Lip/Palate And Clp Surgical Intervention On The Social Integration Of Adolescents In India, 2019 The University of San Francisco
The Impact Of Cleft Lip/Palate And Clp Surgical Intervention On The Social Integration Of Adolescents In India, Mustafa Zahid
Cleft Lip/Palate, a congenital orofacial anomaly, carries an incidence rate of approximately 1 in every 1000 births. In addition to the stigma associated with the condition, the varying levels of cleft severity might result in lower life outcomes which could include lower cognitive ability, physical and psychological well-being, social and behavioral outcomes of adolescents. This paper focuses on the social integration element of life outcomes, which is composed of the social inclusion and prosocial behavior of the adolescent. Despite the affordability of restorative surgeries, patients in rural areas of Low and Middle-Income Countries (LMICs) such as India face accessibility ...
Impact Belize 2010 Executive Report, 2019 Western Kentucky University
Impact Belize 2010 Executive Report, Ritchie D. Taylor, Jordan Norris, Molly Calico, Bernie Strenecky, Daniel Carter, Dawn Garrett Wright, Eve Main, Bonny Petty, Molly Kerby, Jill Norris
No abstract provided.
Incorporating Oral Health Care In Pediatric Primary Care Practice, 2019 Valparaiso University
Incorporating Oral Health Care In Pediatric Primary Care Practice, Salamatu Yusif
Evidence-Based Practice Project Reports
The most common chronic disease in childhood is dental caries and is more prevalent than asthma and hay fever (HHS, 2000). Data show that in the United States from 2011-2014, 24% of children aged 2-5 years had experienced dental caries in their primary teeth, with 11% having untreated caries (Dye et al., 2017). Primary care clinicians have an important role to play in promoting children’s oral health as much as dentists because they have more contact with children. The purpose of this evidence-based practice project was to integrate an evidence-based oral health program for children in a pediatric primary ...
Poor Ergonomics And Neck Flexion: Evaluating The Prevalence Of Musculoskeletal Neck Pain In Dental Hygiene Students, 2019 University of New Mexico, Albuquerque
Poor Ergonomics And Neck Flexion: Evaluating The Prevalence Of Musculoskeletal Neck Pain In Dental Hygiene Students, Justine E. Stambaugh
Dental Hygiene ETDs
Proper ergonomics are important to minimize operator fatigue and discomfort. Poor ergonomics has been proven to be the leading factor in developing musculoskeletal disorders. Musculoskeletal disorders are one of the most important occupational health issues. Studies have been conducted in the past to investigate dental professionals and the risk for developing work-related musculoskeletal disorders and found this occupational group at higher risk. However, research on dental hygiene students is lacking. The purpose of this study was to investigate the prevalence of dental hygiene students being affected by musculoskeletal pain in the neck region in early dental hygiene education and if ...
Long Term Functional And Esthetic Outcomes After Fibula Free Flap Reconstruction Of The Mandible, I. Petrovic, R. Blaser, Timothy Blackwell, C. Mccarthy, I. Ganley, S. Patel, P. Cordeiro, J.P. Shah
Stratford Campus Research Day
Objectives: To report functional and esthetic outcomes, after fibula free flap (FFF) reconstruction of the mandible for oral cancer, assessed by physicians, non-clinicians and patients.
Materials and Methods: Twenty-five long term survivors from oral cancer after FFF reconstruction were recalled for head and neck examination by surgeons and patient reported outcomes, using EORTC, QLQ C-30, H&N-35 and FACE-Q questionnaires.
Results: Physicians reported 64% restoration of functionality compared to normal. Patients reported high scores on QLQ-C30, but lower scores on H&N-35. Esthetic scores were reported higher by clinicians than non-clinicians. The decline in function and appearance was attributed to ...
Transcriptional Influence Of Retinoic Acid And Its Effects On Angiogenesis Of Murine Salivary Glands., 2019 University of Louisville
Transcriptional Influence Of Retinoic Acid And Its Effects On Angiogenesis Of Murine Salivary Glands., Isaac Feinn
College of Arts & Sciences Senior Honors Theses
Salivary gland hypofunction is a major disorder of salivary glands, and can arise either from diseases such as xerostomia, or from defective epithelial morphogenesis during embryogenesis. Hundreds of thousands of individuals suffer from dry mouth, and there is currently no restorative therapy for these patients. Investigation of salivary gland developmental biology will inform regenerative therapies. Currently it is known that retinoic acid (RA), the biologically active form of Vitamin A, is required for proper development of the salivary gland, but little is known about its cellular mechanism regulating organogenesis. This study sought to analyze salivary gland development in Rdh10 knock ...
Xerostomia: A Comprehensive Review, 2019 Wayne State University
Xerostomia: A Comprehensive Review, Danevin Putrus
Honors College Theses
This thesis will be highlighting the condition known as Xerostomia. Xerostomia is the condition also known as “dry mouth”. This condition affects many people all throughout the world with symptoms causing bad breath, discomfort, difficulty speaking and many other. The seriousness of this condition can lead to cardiovascular disease, dementia, respiratory infections, diabetes mellitus, rheumatoid arthritis, and even cancer (Absolutedental.com). Currently there is not any one specific solution for the condition although many have been proposed. Throughout the thesis I will closely examine former research studies, current solutions proposed, and propose my own study and solution based on research ...
Differential Microrna Expression Of Mir-21 And Mir-155 With Oral Cancer Extracellular Vesicles In Response To Melationin, 2019 University of Nevada, Las Vegas
Differential Microrna Expression Of Mir-21 And Mir-155 With Oral Cancer Extracellular Vesicles In Response To Melationin, Matthew Hunsaker, Greta Barba, Karl Kingsley, Katherine M. Howard
Dental Medicine Faculty Publications
Objective: Extracellular vesicles derived from oral cancer cells, which include Exosomes and Oncosomes, are membranous vesicles secreted into the surrounding extracellular environment. These extracellular vesicles can regulate and modulate oral squamous cell carcinoma (OSCC) progression through the horizontal transfer of bioactive molecules including proteins, lipids and microRNA (miRNA). The primary objective of this study was to examine the potential to isolate and evaluate extracellular vesicles (including exosomes) from various oral cancer cell lines and to explore potential differences in miRNA content. Methods: The OSCC cell lines SCC9, SCC25 and CAL27 were cultured in DMEM containing 10% exosome-free fetal bovine serum ...
The Q Rule In Bacteriodetes And The Identification And Characterization Of Porphyromonas Gingivalis Glutaminyl Cyclase., 2019 University of Louisville
The Q Rule In Bacteriodetes And The Identification And Characterization Of Porphyromonas Gingivalis Glutaminyl Cyclase., John Andrew Houston
Electronic Theses and Dissertations
Background: Porphyromonas gingivalis, a major pathogen associated with chronic periodontitis, secretes variety of proteins, majority of which begins with glutamine. Several of these proteins were found with pyroglutamate (pGlu) at N-terminus suggesting the presence of this posttranslational modification pathway in P.gingivalis. The observation that N-terminal glutamine is over-represented as the first amino acid after signal peptide cleavage, and subsequent confirmation of pGlu formation on the nascent protein via mass spectrometry, led us to conclude that an enzyme must be present as the executor of this reaction. Hypothesis: PG2157 is a glutaminyl cyclase and is responsible for the cyclization of ...
Development Of Bar-Peptide Nanoparticles And Electrospun Fibers For The Prevention And Treatment Of Oral Biofilms., 2019 University of Louisville
Development Of Bar-Peptide Nanoparticles And Electrospun Fibers For The Prevention And Treatment Of Oral Biofilms., Mohamed Yehia Mahmoud
Electronic Theses and Dissertations
Background: Periodontal diseases are globally prevalent inflammatory disorders that affect ~47% of U.S adults. Porphyromonas gingivalis (Pg) has been identified as a “keystone” pathogen that disrupts host-microbe homeostasis and contributes to the initiation and progression of periodontitis. Pg associates with oral streptococci in supragingival plaque and this interaction represents a potential target for therapeutic intervention. Previously our group developed a peptide (designated BAR), that potently inhibits Pg/Streptococcus gordonii (Sg) adherence in vitro and Pg virulence in a murine model of periodontitis. While efficacious, BAR (SspB Adherence Region) provided transient inhibition and required higher concentrations of BAR to disrupt ...
Marginal Staining Between Pressed Lithium Disilicate Ceramic Crowns And Direct Restorative Materials By Various Fluids : A Microleakage Study., Sarah Ann Jestel
Electronic Theses and Dissertations
When treating patients with existing restorations in which indirect restoration placement is indicated and crown lengthening surgery is contraindicated, dentists may choose to finish the crown margin on an existing restoration. The interface between the two dental restorations (resin composite and ceramic crown) may be more susceptible to microleakage and fluid staining, reducing restoration longevity. In this study, 80 extracted molars received indirect restoration margins finished on different direct restorative materials (resin-modified glass ionomer and conventional, flowable, and bulk fill nano-hybrid resin composite) and subjected to common staining fluids of coffee, tea, red wine, or Coca-Cola. If the clinician must ...
Microleakage - The Main Culprit In Bracket Bond Failure?, 2019 The University of Medicine and Pharmacy, Cluj Napoca, Romania
Microleakage - The Main Culprit In Bracket Bond Failure?, Ioana Roxana Bordea, Adina Sîrbu, Ondine Lucaciu, Aranka Ilea, Radu Septimiu Câmpian, Doina Adina Todea, Teodora Gabriela Alexescu, Maria Aluaș, Corina Budin, Andreea Simona Pop
Journal of Mind and Medical Sciences
Microleakage is the most common cause of bracket debonding. Moreover, different thermal expansion coefficients between the enamel, the adhesive, and the bracket bases will cause repeated expansion and contraction, adding more stress to the bonding strength. Debonding represents the failure of the adhesion between the brackets and the tooth enamel. The debonding of brackets from the enamel surface is the result of several factors, such as acid-etching and drying, adhesive application, and the time and type of photo activation. The under polymerization process of composite photo activation may lead to early bracket debonding. Objective. The aim of this research is ...
Prevention Of Oral Mucositis In Cancer Patients, 2019 Valparaiso University
Prevention Of Oral Mucositis In Cancer Patients, Patricia E. Biel
Evidence-Based Practice Project Reports
Oral mucositis [OM] is one of the most severe non-hematological problems related to cancer treatments and can impact quality of life. It is linked to poorer outcomes due to the associated weight loss, pain, dehydration, and risk of developing life-threatening infections. The purpose of this evidence-based practice project was to determine if OM is preventable with the use of an oral care protocol and zinc supplementation when compared to use of oral care protocols alone. The Johns Hopkins Nursing Evidence-Based Practice Model was used to guide project implementation in an outpatient oncology office. Recommendations were developed from an exhaustive review ...
Reliability Of Colour And Hardness Clinical Examinations In Detecting Dentine Caries Severity: A Systematic Review And Meta-Analysis., 2019 University of Nevada, Las Vegas
Reliability Of Colour And Hardness Clinical Examinations In Detecting Dentine Caries Severity: A Systematic Review And Meta-Analysis., Larry Hon, Ahmed Mohamed, Edward Lynch
Dental Medicine Faculty Publications
Dental caries is the most common human infectious disease and is caused by microorganisms producing acids, resulting in changes in dental tissue hardness and colour. However, the accuracy and reliability of dentine colour and hardness as indicators for carious lesion severity has never been assessed in a systematic review. By applying strict criteria, only seven papers (five randomized control trials and two diagnostic studies) were considered for full text qualitative and quantitative assessment. Only three studies produced high quality evidence and only four articles were considered for meta-analysis, as these provided log10 colony forming units (CFU) data from caries biopsies ...
Endocytic Recycling And Vesicular Transport Systems Mediate Transcytosis Of Leptospira Interrogans Across Cell Monolayer, 2019 University of the Pacific
Endocytic Recycling And Vesicular Transport Systems Mediate Transcytosis Of Leptospira Interrogans Across Cell Monolayer, Yang Li, Kai-Xuan Li, Wei-Lin Hu, David M. Ojcius, Jia-Qi Fang, Shi-Jun Li, Xu'ai Lin, Jie Yan
Dugoni School of Dentistry Faculty Articles
Many bacterial pathogens can cause septicemia and spread from the bloodstream into internal organs. During leptospirosis, individuals are infected by contact with Leptospira-containing animal urine-contaminated water. The spirochetes invade internal organs after septicemia to cause disease aggravation, but the mechanism of leptospiral excretion and spreading remains unknown. Here, we demonstrated that Leptospira interrogans entered human/mouse endothelial and epithelial cells and fibroblasts by caveolae/integrin-β1-PI3K/FAK-mediated microfilament-dependent endocytosis to form Leptospira (Lep)-vesicles that did not fuse with lysosomes. Lep-vesicles recruited Rab5/Rab11 and Sec/Exo-SNARE proteins in endocytic recycling and vesicular transport systems for intracellular transport and release ...
In-Vitro Evaluation Of Accuracy Of Conventional And Cad/Cam Removable Partial Denture Frameworks, Pooya Soltanzadeh
Pooya Soltanzadeh, DDS, MS
Purpose: Computer-aided design/computer-aided manufacturing (CAD/CAM) technology is gaining popularity in dentistry, and more recently, to fabricate removable partial dentures (RPD). The purpose of this study was 1) to evaluate the overall accuracy and fit of conventional versus CAD/CAM fabricated printed RPD frameworks based on STL data analysis, and 2) to evaluate the accuracy and fit of each component of the RPD framework. Materials and Methods: A maxillary metal framework was designed for a Kennedy class III modification I situation. The master model was scanned and used to compare the fit and accuracy of the RPD frameworks. A ...
Creating Oral Health Awareness: Happy Teeth Make Healthy Teeth, 2019 CUNY New York City College of Technology
Creating Oral Health Awareness: Happy Teeth Make Healthy Teeth, Roseanna M. Torres, Dirien Santos, Tatyana Aksaeva, Hanna Jo, Nastassia Liaushun, Anty Lam
Publications and Research
No abstract provided.
Insight - April 2019, 2019 University of the Pacific
Insight - April 2019, Dugoni School Of Dentistry
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