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The Role Of Il-6 In Osteogenic And Neurogenic Differentiation Potentials Of Dental Pulp Stem Cells (Dpscs), YongTae Park, Xiaoxing Kou, Songtao Shi 2019 University of Pennsylvania

The Role Of Il-6 In Osteogenic And Neurogenic Differentiation Potentials Of Dental Pulp Stem Cells (Dpscs), Yongtae Park, Xiaoxing Kou, Songtao Shi

Dental Theses

Introduction: Interleukin 6 (IL-6) is a pleiotropic soluble mediator which is involved with many different parts of inflammatory processes. Studies have shown that there is a significantly higher concentration of IL-6 in inflamed pulp tissues when compared to healthy pulp tissues. However, there are no comprehensive studies on how IL-6 can interact with dental pulp stem cells (DPSCs) from healthy (H-DPSCs) and inflamed pulp tissues (I-DPSCs) and how it can affect the differentiation potential of DPSCs. Therefore, I hypothesized that IL-6 can promote osteogenesis while inhibiting neurogenesis from DPSCs. The aims of this study were to investigate the baseline differences ...


Impact Belize 2010 Executive Report, Ritchie D. Taylor, Jordan Norris, Molly Calico, Bernie Strenecky, Daniel Carter, Dawn Garrett Wright, Eve Main, Bonny Petty, Molly Kerby, Jill Norris 2019 Western Kentucky University

Impact Belize 2010 Executive Report, Ritchie D. Taylor, Jordan Norris, Molly Calico, Bernie Strenecky, Daniel Carter, Dawn Garrett Wright, Eve Main, Bonny Petty, Molly Kerby, Jill Norris

Eve Main

No abstract provided.


Xerostomia: A Comprehensive Review, Danevin Putrus 2019 Wayne State University

Xerostomia: A Comprehensive Review, Danevin Putrus

Honors College Theses

This thesis will be highlighting the condition known as Xerostomia. Xerostomia is the condition also known as “dry mouth”. This condition affects many people all throughout the world with symptoms causing bad breath, discomfort, difficulty speaking and many other. The seriousness of this condition can lead to cardiovascular disease, dementia, respiratory infections, diabetes mellitus, rheumatoid arthritis, and even cancer (Absolutedental.com). Currently there is not any one specific solution for the condition although many have been proposed. Throughout the thesis I will closely examine former research studies, current solutions proposed, and propose my own study and solution based on research ...


Microleakage - The Main Culprit In Bracket Bond Failure?, Ioana Roxana Bordea, Adina Sîrbu, Ondine Lucaciu, Aranka Ilea, Radu Septimiu Câmpian, Doina Adina Todea, Teodora Gabriela Alexescu, Maria Aluaș, Corina Budin, Andreea Simona Pop 2019 The University of Medicine and Pharmacy, Cluj Napoca, Romania

Microleakage - The Main Culprit In Bracket Bond Failure?, Ioana Roxana Bordea, Adina Sîrbu, Ondine Lucaciu, Aranka Ilea, Radu Septimiu Câmpian, Doina Adina Todea, Teodora Gabriela Alexescu, Maria Aluaș, Corina Budin, Andreea Simona Pop

Journal of Mind and Medical Sciences

Microleakage is the most common cause of bracket debonding. Moreover, different thermal expansion coefficients between the enamel, the adhesive, and the bracket bases will cause repeated expansion and contraction, adding more stress to the bonding strength. Debonding represents the failure of the adhesion between the brackets and the tooth enamel. The debonding of brackets from the enamel surface is the result of several factors, such as acid-etching and drying, adhesive application, and the time and type of photo activation. The under polymerization process of composite photo activation may lead to early bracket debonding. Objective. The aim of this research is ...


Reliability Of Colour And Hardness Clinical Examinations In Detecting Dentine Caries Severity: A Systematic Review And Meta-Analysis., Larry Hon, Ahmed Mohamed, Edward Lynch 2019 University of Nevada, Las Vegas

Reliability Of Colour And Hardness Clinical Examinations In Detecting Dentine Caries Severity: A Systematic Review And Meta-Analysis., Larry Hon, Ahmed Mohamed, Edward Lynch

Dental Medicine Faculty Publications

Dental caries is the most common human infectious disease and is caused by microorganisms producing acids, resulting in changes in dental tissue hardness and colour. However, the accuracy and reliability of dentine colour and hardness as indicators for carious lesion severity has never been assessed in a systematic review. By applying strict criteria, only seven papers (five randomized control trials and two diagnostic studies) were considered for full text qualitative and quantitative assessment. Only three studies produced high quality evidence and only four articles were considered for meta-analysis, as these provided log10 colony forming units (CFU) data from caries biopsies ...


In-Vitro Evaluation Of Accuracy Of Conventional And Cad/Cam Removable Partial Denture Frameworks, Pooya Soltanzadeh 2019 Selected Works

In-Vitro Evaluation Of Accuracy Of Conventional And Cad/Cam Removable Partial Denture Frameworks, Pooya Soltanzadeh

Pooya Soltanzadeh, DDS, MS

Purpose: Computer-aided design/computer-aided manufacturing (CAD/CAM) technology is gaining popularity in dentistry, and more recently, to fabricate removable partial dentures (RPD). The purpose of this study was 1) to evaluate the overall accuracy and fit of conventional versus CAD/CAM fabricated printed RPD frameworks based on STL data analysis, and 2) to evaluate the accuracy and fit of each component of the RPD framework. Materials and Methods: A maxillary metal framework was designed for a Kennedy class III modification I situation. The master model was scanned and used to compare the fit and accuracy of the RPD frameworks. A ...


Family Postponement Of Medical And Dental Care: The Influence Of Income Level And Financial Hardship, Sara K. Ray, Clinton G. Gudmunson 2019 Iowa State University

Family Postponement Of Medical And Dental Care: The Influence Of Income Level And Financial Hardship, Sara K. Ray, Clinton G. Gudmunson

Clinton G. Gudmunson

Medical and dental care are some of the most expensive expenditures that consumers incur, and they are also some of the most common expenses that families postpone (Gallup, 2015; Kaiser, 2012). The goal of the present is to examine family and financial factors that influence families’ likelihood of delaying healthcare in a predominantly middle and upper income sample. A large body of research framed by the Family Stress Model has used the postponement of healthcare as one of many indicators of family economic pressure that together predict deleterious relationship and developmental outcomes (Gauthier & Furstenberg, 2010). However, only a handful of ...


Injectable Gels With Potential Use In Endodontics, Maksim Montatskiy 2019 Marquette University

Injectable Gels With Potential Use In Endodontics, Maksim Montatskiy

Master's Theses (2009 -)

Objective: To formulate a thermoreversible hydrogel using methyl-cellulose, carbon dots and inorganic salts to achieve physiologically compatible gelation temperature; to test cytotoxic effects of formulation against dental pulp stem cells.Materials/Methods: A 5% w/v methylcellulose (MC) solution was prepared and equal volumes of NaCl aqueous solution were added to make various sodium chloride salt concentrations and reach the final MC concentration of 2.5%. Samples were analyzed using a shear rheometer to monitor complex shear viscosity as a function of temperature to arrive at onset gelation temperature closest to targeted temperature. Carbon dots were synthesized by thermal method ...


The Design And Physical Properties Of An Optimized Chitosan Hydrogel For Potential Use In Endodontics, Hunter Housley 2019 Marquette University

The Design And Physical Properties Of An Optimized Chitosan Hydrogel For Potential Use In Endodontics, Hunter Housley

Master's Theses (2009 -)

Introduction: The aim of this study was to synthesize an optimized chitosan/carbon dot hydrogel and measure its effects on the proliferation of dental pulp stem cells. Methods: 1.5% w/v chitosan hydrogel samples were fabricated with 300 mg/ml aqueous β-glycerol phosphate (β-GP) to create an optimized chitosan with a gelation onset temperature below 37°C. Spermidine-functionalized carbon dots (CDs) were added to test groups in concentrations of 25 µg/ml and 50 µg/ml. Complex shear viscosity of the prepared hydrogel samples was evaluated with a Kinexus pro+ shear rheometer (Malvern Panalytical). Samples were evaluated for cellular ...


The Influence Of Full Coverage Restorations On Pulp Vitality: A Ten-Year Retrospective Study, Abby Yavorek 2019 Marquette University

The Influence Of Full Coverage Restorations On Pulp Vitality: A Ten-Year Retrospective Study, Abby Yavorek

Master's Theses (2009 -)

INTRODUCTION: The incidence of pulpal disease after delivery of a full-coverage crown has been previously described as between 2-19%. The objective of this study was to identify and analyze the factors that contribute to the incidence of NS-RCT after the delivery of single-unit full-coverage restorations. MATERIALS AND METHODS: Insurance claims from 88,409 crown placements in the Delta Dental of Wisconsin Insurance database were analyzed from the years 2008 to 2017. The Cox Regression model was used to analyze the effect of the predictor variables on the survival of the tooth. Untoward events were defined as NS-RCT, tooth extraction, retreatment ...


Insight - April 2019, Dugoni School of Dentistry 2019 University of the Pacific

Insight - April 2019, Dugoni School Of Dentistry

Insight

Whether you are involved in clinical research, biomedical research, the scholarship of teaching and learning, improvement of the health care system, or professional partnerships that advance the field, we aim to spotlight the work of people at the Dugoni School.


Contact Point Spring 2019, Arthur A. Dugoni School of Dentistry 2019 University of the Pacific

Contact Point Spring 2019, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.


Periodontitis And The Elderly: An Overview Of The Disease And Its Impact On An Aging Population, Nicole Grace Weissenfluh 2019 Liberty University

Periodontitis And The Elderly: An Overview Of The Disease And Its Impact On An Aging Population, Nicole Grace Weissenfluh

Senior Honors Theses

Periodontitis affects millions of Americans each year, and is especially prevalent among the elderly. Since periodontitis is a chronic, progressive condition, uninterrupted disease progression leads to irreversible oral damage; therefore, periodontitis often reduces the oral health-related quality of life. Furthermore, research strongly suggests a correlation between periodontitis and other systemic diseases (e.g., cardiovascular disease and diabetes mellitus), highlighting the importance of understanding, treating, and preventing periodontitis. This thesis explores the pathology and etiology of periodontitis, with special focus given to the prevalence and impact of the disease in the elderly population. Additionally, the connection between periodontitis and other systemic ...


Tang Et Al 2019.Pdf, Michael A. Etnier 2019 Western Washington University

Tang Et Al 2019.Pdf, Michael A. Etnier

Michael Etnier


A mature, adult female, offshore killer whale (Orcinus orca) was stranded deceased in Portage Bay, Alaska, in October 2015. Full necropsy examination with histopathology was performed. Consistent with previous studies of offshore killer whales, and thought to be a result of their unique elasmobranch diet, all the teeth were significantly abraded and almost flush with the gingival margin. Age was estimated at 30-35 years based on annuli and growth arrest lines in a remaining tooth. The dentate portion of the mandibles were excised en bloc and
frozen until imaging could be completed. Radiography and computed tomography revealed lesions consistent with ...


Mass Spectrometry-Based Proteomics Analysis Of Bioactive Proteins In Emd That Modulate Adhesion Of Gingival Fibroblast To Improve Bio-Integration Of Dental Implants, David Zuanazzi Machado Jr 2019 The University of Western Ontario

Mass Spectrometry-Based Proteomics Analysis Of Bioactive Proteins In Emd That Modulate Adhesion Of Gingival Fibroblast To Improve Bio-Integration Of Dental Implants, David Zuanazzi Machado Jr

Electronic Thesis and Dissertation Repository

Titanium implants are used in dental practice to replace damaged or lost teeth. The implant needs to integrate with the surrounding gingiva to protect it against bacterial invasion that leads to implant loss. The biointegration is dependent on the implant surface that interacts with proteins from biological fluids to modulate tissues response. Tailoring the surface with specific proteins from the enamel matrix derivative (EMD) would be beneficial to improve the implant-gingiva interface since EMD can affect various cells including gingival fibroblasts. A surface-affinity approach using three different titanium surfaces and saliva was utilized as a model in combination with tandem ...


Diagnosis Of B-Cell Lymphoproliferative Disorder Through Concomitant Management Of Medication-Related Osteonecrosis Of The Jaw: A Case Report, Robert Diecidue, Allen F. Champion, Ruifeng Zhou, James G. Buckley 2019 Thomas Jefferson University

Diagnosis Of B-Cell Lymphoproliferative Disorder Through Concomitant Management Of Medication-Related Osteonecrosis Of The Jaw: A Case Report, Robert Diecidue, Allen F. Champion, Ruifeng Zhou, James G. Buckley

Department of Oral and Maxillofacial Surgery Faculty Papers

No abstract provided.


A Systematic Review Of The Caries Prevalence Among Children Living In Chernobyl Fallout Countries, Michael Wolgin, Nicole Filina, Valentyn Dvornyk, Edward Lynch, Andrej M. Kielbassa 2019 Danube Private University

A Systematic Review Of The Caries Prevalence Among Children Living In Chernobyl Fallout Countries, Michael Wolgin, Nicole Filina, Valentyn Dvornyk, Edward Lynch, Andrej M. Kielbassa

Dental Medicine Faculty Publications

The present study analyzed the data concerning the caries prevalence in children born and permanently residing in Chernobyl fallout areas. Setting forth to evaluate if differences regarding the caries prevalence can be observed compared to non-contaminated sites of affected East European countries. Methods used to assess the caries prevalence were limited to DMFT/dmft (decayed, missing and filled teeth) for the primary and the permanent dentitions. The databases PubMed, EMBASE/Ovid, Cochrane Library, Scopus, and eLIBRARY were consulted for the electronic literature search...(Please see text for full abstrast)


Trident - March 2019, Arthur A. Dugoni School of Dentistry 2019 University of the Pacific

Trident - March 2019, Arthur A. Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry.


Implant Impression Accuracy Of Parallel And Non-Parallel Implants: A Comparative In-Vitro Analysis Of Open And Closed Tray Techniques, Motaz S. Osman, Hassan M. Ziada, Neamat H. Abubakr, Ahmed M. Suliman 2019 University of Khartoum

Implant Impression Accuracy Of Parallel And Non-Parallel Implants: A Comparative In-Vitro Analysis Of Open And Closed Tray Techniques, Motaz S. Osman, Hassan M. Ziada, Neamat H. Abubakr, Ahmed M. Suliman

Dental Medicine Faculty Publications

Background The outcome of the evaluation of impression techniques accuracy may improve the selection criteria for an ideal technique. The aim was to evaluate the accuracy of the open and closed tray techniques for implant impressions, in a partially edentulous maxilla, replaced with a three-unit fixed partial denture, as well as to assess the effect of implants parallelism on accuracy. Material and methods This is an experimental in vitro study to evaluate impressions accuracy of a simulated area restored with an implant retained FPD, using the open and closed tray implant impression techniques. The effect of implant position angulation, parallelism ...


Silver Diamine Fluoride Versus Sodium Fluoride For Arresting Dentine Caries In Children: A Systematic Review And Meta-Analysis, Alice Trieu, Ahmed Mohamed, Edward Lynch 2019 University of Nevada, Las Vegas

Silver Diamine Fluoride Versus Sodium Fluoride For Arresting Dentine Caries In Children: A Systematic Review And Meta-Analysis, Alice Trieu, Ahmed Mohamed, Edward Lynch

Dental Medicine Faculty Publications

Dental caries can compromise quality of life and is associated with demineralization of tooth structure by organic acids produced by microorganisms. This study systematically reviewed the dentine caries arrest capabilities of silver diamine fluoride (SDF) and sodium fluoride (NaF). A comprehensive search strategy was developed to identify the relevant publications in electronic databases and hand searched journals and reviews (to March 2018). By applying strict inclusion and exclusion criteria, only six papers (two randomized controlled trials, two follow-up articles and two secondary statistical analysis studies) were considered for full text qualitative and quantitative assessment. The included studies were critically appraised ...


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