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196,570 full-text articles. Page 3 of 4953.

Computational Modeling Of Cilia Dynamics In The Human Airways, Uduak George 2019 San Diego State University

Computational Modeling Of Cilia Dynamics In The Human Airways, Uduak George

Biology and Medicine Through Mathematics Conference

No abstract provided.


Dermal Lymphatic Capillaries Do Not Obey Murray's Law, Anne Talkington, Reema Davis, Nicholas Datto, Emma Goodwin, Kathleen Caron, Laura Miller 2019 University of North Carolina at Chapel Hill

Dermal Lymphatic Capillaries Do Not Obey Murray's Law, Anne Talkington, Reema Davis, Nicholas Datto, Emma Goodwin, Kathleen Caron, Laura Miller

Biology and Medicine Through Mathematics Conference

No abstract provided.


Effects Of Predator Diversity On Optimal Communities For Prey Suppression, Amanda N. Laubmeier 2019 University of Nebraska - Lincoln

Effects Of Predator Diversity On Optimal Communities For Prey Suppression, Amanda N. Laubmeier

Biology and Medicine Through Mathematics Conference

No abstract provided.


Network Analyses Of Glomerular Capillaries, Jason Cory Brunson, Justin Sardi, Mark Terasaki 2019 UConn Health

Network Analyses Of Glomerular Capillaries, Jason Cory Brunson, Justin Sardi, Mark Terasaki

Biology and Medicine Through Mathematics Conference

No abstract provided.


Is The Selective Tuning Model Of Visual Attention Still Relevant?, John K. Tsotsos 2019 York University

Is The Selective Tuning Model Of Visual Attention Still Relevant?, John K. Tsotsos

MODVIS Workshop

No abstract provided.


Does Tcdd Exposure Alter Β7-Integrin Expression On Mouse B Cells?, Sebastian Ramos 2019 University of Northern Colorado

Does Tcdd Exposure Alter Β7-Integrin Expression On Mouse B Cells?, Sebastian Ramos

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

Activated aryl hydrocarbon receptor with ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters immune responses, including immunoglobulin A (IgA). Manipulation of antibody production via this ligand-activated receptor may provide a novel approach to enhance vaccination in the intestines. The present study aimed to explain the mechanism responsible for increased levels of fecal IgA in TCDD-treated mice. We hypothesized that TCDD enhances migration of B cells from non-intestinal tissue to the intestines. Here we predicted that β7-integrin, an essential protein for B cell migration into the intestines, would be upregulated by TCDD exposure on B cells. Female C57BL/6 mice were treated ...


Trefoil Factor 1 (Tff1) Expression In E3 And Ewd8 Breast Cancer Cell Lines, Jazmyn Mosqueda-Banuelos 2019 University of Northern Colorado

Trefoil Factor 1 (Tff1) Expression In E3 And Ewd8 Breast Cancer Cell Lines, Jazmyn Mosqueda-Banuelos

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

The ability to identify and treat cancer early can drastically improve patient survival outcomes. While much effort is placed on anti-cancer therapeutics, a developing area of interest is the identification of cancer biomarkers for the early detection of different types of cancer. Trefoil factors (TFFs) are a family of proteins whose known functions suggest that they may be major contributors to cancer; however, these proteins are understudied in a disease state like cancer. In this work, we identify expression of TFF1 among varying cancer types. We then investigate the correlation between varying levels of TFF1 expression and the aggressiveness of ...


Investigating The Antidiabetic Effect Of Metformin On Pyruvate Carboxylase, Guadalupe A. Solis 2019 University of Northern Colorado

Investigating The Antidiabetic Effect Of Metformin On Pyruvate Carboxylase, Guadalupe A. Solis

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

Metformin is the most commonly prescribed treatment for type II diabetes. While the clinical effects of this generic drug are established, exact targets of metformin action remain unclear. The hypothesis of the present study was that metformin lowers blood glucose through inhibition of pyruvate carboxylase (PC), an enzyme catalyzing the first committed step of gluconeogenesis. Because metformin is relatively low cost, it is widely accessible to communities worldwide; currently, 150 million individuals depend on metformin for treatment. Thorough investigation of all targets involved in action of metformin becomes crucial, as it further explains the adverse effects of the drug. The ...


Investigating Drivers Of Dengue Emergence In Cordoba, Argentina, Michael Andrew Robert, Rachel Sippy, Anna M. Stewart-Ibarra, Rebecca C. Christofferson, Helen J. Wearing, Elizabet L. Estallo 2019 University of the Sciences of Philadelphia

Investigating Drivers Of Dengue Emergence In Cordoba, Argentina, Michael Andrew Robert, Rachel Sippy, Anna M. Stewart-Ibarra, Rebecca C. Christofferson, Helen J. Wearing, Elizabet L. Estallo

Biology and Medicine Through Mathematics Conference

No abstract provided.


Understanding The Role Of Macrophages In Lung Inflammation Through Mathematical Modeling, Sarah B. Minucci 2019 Virginia Commonwealth University

Understanding The Role Of Macrophages In Lung Inflammation Through Mathematical Modeling, Sarah B. Minucci

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling The Waning And Boosting Of Immunity: A Case Study Of Pertussis In Sweden, Lauren M. Childs 2019 Virginia Polytechnic Institute and State University

Modeling The Waning And Boosting Of Immunity: A Case Study Of Pertussis In Sweden, Lauren M. Childs

Biology and Medicine Through Mathematics Conference

No abstract provided.


Conserved, Breed-Dependent, And Subline-Dependent Innate Immune Responses Of Fayoumi And Leghorn Chicken Embryos To Newcastle Disease Virus Infection, Megan A. Schilling, Sahar Memari, Meredith Cavanaugh, Robab Katani, Melissa S. Deist, Jessica Radzio-Basu, Susan J. Lamont, Joram J. Buza, Vivek Kapur 2019 The Pennsylvania State University

Conserved, Breed-Dependent, And Subline-Dependent Innate Immune Responses Of Fayoumi And Leghorn Chicken Embryos To Newcastle Disease Virus Infection, Megan A. Schilling, Sahar Memari, Meredith Cavanaugh, Robab Katani, Melissa S. Deist, Jessica Radzio-Basu, Susan J. Lamont, Joram J. Buza, Vivek Kapur

Susan J. Lamont

Newcastle disease virus (NDV) is a threat to the global poultry industry, but particularly for smallholder farmers in low- and middle-income countries. Previous reports suggest that some breeds of chickens are less susceptible to NDV infection, however, the mechanisms contributing to this are unknown. We here examined the comparative transcriptional responses of innate immune genes to NDV infection in inbred sublines of the Fayoumi and Leghorn breeds known to differ in their relative susceptibility to infection as well as at the microchromosome bearing the major histocompatability complex (MHC) locus. The analysis identified a set of five core genes, Mx1, IRF1 ...


Functional Organization Of Cortical Maps For Ocular Dominance And Light-Dark Polarity In Primary Visual Cortex, sohrab najafian, Jian Zhong Jin, Jose-Manuel Alonso 2019 SUNY College of Optometry

Functional Organization Of Cortical Maps For Ocular Dominance And Light-Dark Polarity In Primary Visual Cortex, Sohrab Najafian, Jian Zhong Jin, Jose-Manuel Alonso

MODVIS Workshop

No abstract provided.


Mathematical Modeling Of Energy Consumption In The Acute Inflammatory Response, Ivan Ramirez Zuniga 2019 University of Pittsburgh

Mathematical Modeling Of Energy Consumption In The Acute Inflammatory Response, Ivan Ramirez Zuniga

Biology and Medicine Through Mathematics Conference

No abstract provided.


An Observational Study With The Janssen Autism Knowledge Engine (Jake((R))) In Individuals With Autism Spectrum Disorder, Seth L. Ness, Jean A. Frazier 2019 Janssen Research & Development

An Observational Study With The Janssen Autism Knowledge Engine (Jake((R))) In Individuals With Autism Spectrum Disorder, Seth L. Ness, Jean A. Frazier

Jean A. Frazier

Objective: The Janssen Autism Knowledge Engine (JAKE(R)) is a clinical research outcomes assessment system developed to more sensitively measure treatment outcomes and identify subpopulations in autism spectrum disorder (ASD). Here we describe JAKE and present results from its digital phenotyping (My JAKE) and biosensor (JAKE Sense) components.

Methods: An observational, non-interventional, prospective study of JAKE in children and adults with ASD was conducted at nine sites in the United States. Feedback on JAKE usability was obtained from caregivers. JAKE Sense included electroencephalography, eye tracking, electrocardiography, electrodermal activity, facial affect analysis, and actigraphy. Caregivers of individuals with ASD reported behaviors ...


Computations Of Top-Down Attention By Modulating V1 Dynamics, David Berga, Xavier Otazu 2019 Computer Vision Center, Autonomous University of Barcelona

Computations Of Top-Down Attention By Modulating V1 Dynamics, David Berga, Xavier Otazu

MODVIS Workshop

The human visual system processes information defining what is visually conspicuous (saliency) to our perception, guiding eye movements towards certain objects depending on scene context and its feature characteristics. However, attention has been known to be biased by top-down influences (relevance), which define voluntary eye movements driven by goal-directed behavior and memory. We propose a unified model of the visual cortex able to predict, among other effects, top-down visual attention and saccadic eye movements. First, we simulate activations of early mechanisms of the visual system (RGC/LGN), by processing distinct image chromatic opponencies with Gabor-like filters. Second, we use a ...


Plenary Talk: How Aids Prevalence Impacts The Emergence Of Antibiotic Resistance In Bacterial Infections, Nina Fefferman 2019 University of Tennessee, Knoxville

Plenary Talk: How Aids Prevalence Impacts The Emergence Of Antibiotic Resistance In Bacterial Infections, Nina Fefferman

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Generalized Model Of The Transmission Dynamics Of Leishmaniasis With Multiple Time Delays, Ephraim Agyingi 2019 Rochester Institute of Technology

A Generalized Model Of The Transmission Dynamics Of Leishmaniasis With Multiple Time Delays, Ephraim Agyingi

Biology and Medicine Through Mathematics Conference

No abstract provided.


Stochastic Modeling Of Neuronal Transport In Various Cellular Geometries, Abhishek Choudhary Mr., Peter Kramer 2019 Rensselaer Polytechnic Institute

Stochastic Modeling Of Neuronal Transport In Various Cellular Geometries, Abhishek Choudhary Mr., Peter Kramer

Biology and Medicine Through Mathematics Conference

No abstract provided.


Risk Structured Model Of Cholera Infections In Cameroon, Fnu Eric Ngang Che, Abdul-Aziz Yakubu Dr. 2019 Howard University

Risk Structured Model Of Cholera Infections In Cameroon, Fnu Eric Ngang Che, Abdul-Aziz Yakubu Dr.

Biology and Medicine Through Mathematics Conference

No abstract provided.


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