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Quantitative Evaluation Of Clinostomum Marginatum Distribution In The Fish Host (Perca Flavescens): Investigation Of The Impact On Functional Performance, Doiba KI Eshofonie, Precious Freeman 2017 Lynchburg College

Quantitative Evaluation Of Clinostomum Marginatum Distribution In The Fish Host (Perca Flavescens): Investigation Of The Impact On Functional Performance, Doiba Ki Eshofonie, Precious Freeman

Student Scholar Showcase

Doiba Eshofonie & Precious Freeman

Mentor: Takashi Maie

2017 Student Scholar Showcase

Quantitative evaluation of Clinostomum marginatum distribution in the fish host (Perca flavescens): Investigation of the impact on functional performance

Clinostomum marginatum is a trematode commonly found in freshwater fish. The adult C. marginatum stays in its definitive avian host’s mouth and throat. It releases eggs upon contact in water and the eggs hatch into a free-swimming miracidia, which infects an aquatic snail as the first intermediate host. The miracidia, then, develops into a cercaria and leaves the snail to find a fish as its second intermediate host. The ...


The Efficacy And Safety Of Six-Weeks Of Pre-Workout Supplementation In Resistance Trained Rats, Justin P. Canakis 2017 College of William and Mary

The Efficacy And Safety Of Six-Weeks Of Pre-Workout Supplementation In Resistance Trained Rats, Justin P. Canakis

Undergraduate Honors Theses

Pre-workout supplements (PWSs) contain a cocktail of ingredients that are marketed to increase energy levels, endurance, and muscle power. PWSs are not regulated by the Food and Drug Administration (FDA) and have a history of causing adverse side effects. The goal of this study is to independently analyze the efficacy and safety of Pro Supps Mr. Hyde (MH) in resistance trained rats. Data suggest that six weeks of pre-workout supplementation in rats undergoing resistance training results in modest efficacy with improvement in amount lifted but no change in muscle mass. Urinary creatine tests and vascular reactivity tests were selected as ...


The Fitness Effects Of Biofilm Formation And Toxin Production In Natural Yeast Isolates, Bernadette M. Deschaine 2017 College of William and Mary

The Fitness Effects Of Biofilm Formation And Toxin Production In Natural Yeast Isolates, Bernadette M. Deschaine

Undergraduate Honors Theses

Biofilms are complex, cooperative microbial communities encased in an extracellular matrix and attached to a surface. Biofilms are ubiquitous in virtually all environments and perform many important ecological functions. They can also cause dangerous, drug-resistant infections. There is thus great interest in studying biofilms and how to combat them.

The research presented here uses natural isolates of the budding yeast, Saccharomyces cerevisiae, to explore the fitness effects of biofilm formation. Biofilm-forming and non-biofilm-forming strains were grown alone and in mixed colonies with and without inducing biofilm formation, and the change in biofilm-strain frequency used to determine what conditions favor biofilm-forming ...


Investigating The Effects Of Pre-Laboratory Videos With Associated Questions On The Performance And Overall Laboratory Experience Of Organic Chemistry Students, Shareef Gamal Mohamed Kotb 2017 Merrimack College

Investigating The Effects Of Pre-Laboratory Videos With Associated Questions On The Performance And Overall Laboratory Experience Of Organic Chemistry Students, Shareef Gamal Mohamed Kotb

Health Sciences Student Work

Background: Teachers struggle communicating ideas to students (Moreno et al, 2001). One of the aspects of teaching that’s most concerning is when students experience cognitive overload: the total effort exerted by working memory to grasp new information (Mayer, et al, 2002). The educational community found that introducing multimedia in learning minimizes cognitive overload (Mayer, et al, 2002). Little research has related to undergraduate chemistry classes, specifically the relationship between organic chemistry pre-laboratory multimedia and student learning. Purpose: The purpose of this capstone is to investigate the subjective efficacy of integrating pre-laboratory videos for lab preparation in an undergraduate organic ...


Reactivity Of Ketyl And Acetyl Radicals From Direct Solar Actinic Photolysis Of Aqueous Pyruvic Acid, Alexis J. Eugene, Marcelo I. Guzman 2017 University of Kentucky

Reactivity Of Ketyl And Acetyl Radicals From Direct Solar Actinic Photolysis Of Aqueous Pyruvic Acid, Alexis J. Eugene, Marcelo I. Guzman

Chemistry Faculty Publications

The variable composition of secondary organic aerosols (SOA) contributes to the large uncertainty for predicting radiative forcing. A better understanding of the reaction mechanisms leading to aerosol formation such as for the photochemical reaction of aqueous pyruvic acid (PA) at λ ≥ 305 nm can contribute to constrain these uncertainties. Herein, the photochemistry of aqueous PA (5-300 mM) continuously sparged with air is re-examined in the laboratory under comparable irradiance at 38° N at noon on a summer day. Several analytical methods are employed to monitor the time series of the reaction, including (1) the derivatization of carbonyl (C═O) functional ...


Pulmonary Surfactant Fortified With Cath-2 As A Novel Therapy For Bacterial Pneumonia, Brandon J. Baer 2017 University of Western Ontario

Pulmonary Surfactant Fortified With Cath-2 As A Novel Therapy For Bacterial Pneumonia, Brandon J. Baer

Western Research Forum

Background: Bacterial pneumonia is a leading cause of death worldwide, with high mortality rates persisting even after antibiotic treatment. Current treatments for pneumonia involve administration of antibiotics, however after the bacteria are killed they release toxic substances that induce inflammation and lung dysfunction. Host defense peptides represent a potential solution to this problem through their ability to down regulate inflammation. However, effective delivery to the lung is difficult because of the complex branching structure of the airways. My study addresses this delivery problem by using exogenous surfactant, a pulmonary delivery vehicle capable of improving spreading of these peptides throughout the ...


Assessment Of Olfactory-Based Social Recognition: Designing A Paradigm For Marmosets, Stephanie Womack 2017 University of Nebraska at Omaha

Assessment Of Olfactory-Based Social Recognition: Designing A Paradigm For Marmosets, Stephanie Womack

Student Research and Creative Activity Fair

Navigation of the social world depends largely on one’s responsiveness to social stimuli and information from a wide range of senses can be used to discriminate between individuals. Mammals use several sensory modes to communicate and respond to their surroundings, but olfaction is the dominant sense across most species. Chemosignals provide a wealth of information including sex, age, reproductive status, and individual identity. Currently, assessment of olfaction is largely limited to the habituation-dishabituation paradigm or the two-choice discrimination task used primarily in rodents. These paradigms are limited by their reliance on inherent reward of interaction with stimuli without providing ...


Gait Biomechanics In Patients With Peripheral Artery Disease After Revascularization, Sarah Baker 2017 University of Nebraska at Omaha

Gait Biomechanics In Patients With Peripheral Artery Disease After Revascularization, Sarah Baker

Student Research and Creative Activity Fair

Peripheral artery disease (PAD) is a cardiovascular disease manifesting blockages to arteries while limiting blood flow to the legs. Patients with PAD have pain/tingling in calves, thighs, and/or buttocks emanating by physical activity called intermittent claudication. PAD causes physical function limitations and increases cardiovascular morbidity by 3-6 times. PAD becomes particularly more prevalent with age. Patients with PAD walk differently than their healthy counterparts. Surgical revascularization to restore blood flow is the typical intervention, but whether walking patterns are restored following surgery has not been studied. This study compared walking patterns of patients with PAD at baseline and ...


Environmental Changes Turn On The Sinorhizobium Melitloti Exor-Exos/Chvi (Rsi) Host Invasion Switch, Shari N. Walcott 2017 The Graduate Center, City University of New York

Environmental Changes Turn On The Sinorhizobium Melitloti Exor-Exos/Chvi (Rsi) Host Invasion Switch, Shari N. Walcott

All Dissertations, Theses, and Capstone Projects

The free-living Gram-negative soil bacterium, Sinorhizobium meliloti, must switch into its host-invading form in order to infect the root hairs of the host plant, alfalfa (Medicago sativa), and establish a nitrogen-fixing symbiosis. The activation of the switch is believed to occur inside the infection chamber that is formed by curling of the root hairs. It is not fully understood what signals in the environment of the root hairs trigger and infection chamber S. meliloti to switch into a host-invading form since these signals were not extensively examined until now. This switch can be observed directly, due to the inverse relationship ...


Associations Of Health Club Membership With Physical Activity And Cardiovascular Health, Elizabeth C. Schroeder, Gregory Welk, Warren D. Franke, Duck-Chul Lee 2017 University of Illinois at Chicago

Associations Of Health Club Membership With Physical Activity And Cardiovascular Health, Elizabeth C. Schroeder, Gregory Welk, Warren D. Franke, Duck-Chul Lee

Kinesiology Publications

Introduction This study evaluates whether a health club membership is associated with meeting the US physical activity (PA) guidelines and/or favorable cardiovascular health.

Methods Using cross-sectional data of health club members (n = 204) and non-members (n = 201) from April to August 2013, this is the first study to our knowledge to examine a health club membership in relation to objectively measured cardiovascular health indicators including resting blood pressure, resting heart rate, body mass index, waist circumference, and cardio respiratory fitness based on a non-exercise test algorithm. To determine the total PA and sedentary time, this study used a comprehensive ...


A New Hcc Model Induced By Co-Overexpression Fgf19 And Met In Mice, junyan tao 8598903, Morgan Preziosi, sucha singh, xin chen, Satdarshan (Paul) Singh Monga 2017 upmc

A New Hcc Model Induced By Co-Overexpression Fgf19 And Met In Mice, Junyan Tao 8598903, Morgan Preziosi, Sucha Singh, Xin Chen, Satdarshan (Paul) Singh Monga

Hepatobiliary Cancers: Pathobiology and Translational Advances

No abstract provided.


Survival Model Of Intrahepatic Cholangiocarcinoma; Sex As A Biological Variable, Mary A. Phillippi, Justin L. Mott, Cody J. Wehrkamp, Ying Xie, David Oupicky, Ashley M. Mohr, Bailey A. Stringham 2017 University of Nebraska Medical Center

Survival Model Of Intrahepatic Cholangiocarcinoma; Sex As A Biological Variable, Mary A. Phillippi, Justin L. Mott, Cody J. Wehrkamp, Ying Xie, David Oupicky, Ashley M. Mohr, Bailey A. Stringham

Hepatobiliary Cancers: Pathobiology and Translational Advances

No abstract provided.


Determination Of Meloxicam In Egg Whites And Yolks Using Reverse Phase Chromatography, Sherry Cox, Marcy Souza, Joan Bailey, Molly White, Krissten Gordon 2017 University of Tennessee, Knoxville

Determination Of Meloxicam In Egg Whites And Yolks Using Reverse Phase Chromatography, Sherry Cox, Marcy Souza, Joan Bailey, Molly White, Krissten Gordon

Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences

A new method of analysis has been developed and validated for the determination of meloxicam in egg whites and yolks. Following a liquid extraction for the whites and a solid phase extraction for the yolks, samples were separated on an XBridge C18 column and quantified using UV detection at 360 nm. The mobile phase was a mixture of water with glacial acetic acid and acetonitrile, with a flow rate of 1 mL/min. The procedure produced a linear curve over the concentration range 5 – 1500 ng/mL with a lower limit of quantification of 5 ng/mL. Intra- and ...


The Hetz Gene Regulates Heterocyst Formation In Anabaena Sp. Strain Pcc 7120, Patrick Videau, Vaille Swenson, Michael Gaylor, S M. O'Hanlon, L M. Cozy 2017 Dakota State University

The Hetz Gene Regulates Heterocyst Formation In Anabaena Sp. Strain Pcc 7120, Patrick Videau, Vaille Swenson, Michael Gaylor, S M. O'Hanlon, L M. Cozy

Faculty Research & Publications

To form a complex multicellular organism, stem cells must differentiate into each cell/tissue type along proper spatiotemporal scales. The study of differentiation and organismal development has historically been conducted in prokaryotes due to their genetic and morphological simplicity. Anabaena sp. strain PCC 7120 is a multicellular filamentous cyanobacterium that differentiates a morphologically distinct secondary cell type, the heterocyst, in response to a lack of combined environmental nitrogen. Heterocysts are regularly spaced along filaments and fix atmospheric dinitrogen to maintain organismal viability in its absence. Previous work suggested that the hetZ gene is involved in heterocyst differentiation, but the insertional ...


A Comparison Of Benthic Macroinvertebrate Assemblages Between Perennial And Intermittent Headwater Streams Of The Mattole River In Northern California, Usa, Mason S. London 2017 Humboldt State University

A Comparison Of Benthic Macroinvertebrate Assemblages Between Perennial And Intermittent Headwater Streams Of The Mattole River In Northern California, Usa, Mason S. London

Theses and projects

Intermittent streams are common throughout the world and comprise 60% or more of total river lengths in the conterminous United States. Despite their prevalence, intermittent streams are understudied, particularly first-order headwater streams, which are vital for maintaining the function, health and biotic diversity of river networks. In June 2016, I sampled five intermittent and five perennial headwater streams in the Mattole River watershed in northwestern coastal California, USA, to compare benthic macroinvertebrate (BMI) assemblages between intermittent and perennial streams. BMI samples were collected using a 500µm mesh D-net at eight randomly located riffles along a 150-m reach, and then composited ...


Rat Hind Limb Nociceptive Withdrawal Response To Heat And Mechanical Stimuli Depends On Initial Position Of The Paw But Not Stimulus Location, Giavanna Verdi 2017 James Madison University

Rat Hind Limb Nociceptive Withdrawal Response To Heat And Mechanical Stimuli Depends On Initial Position Of The Paw But Not Stimulus Location, Giavanna Verdi

Senior Honors Projects, 2010-current

Mammals rapidly withdraw their hind limb in response to noxious stimulation, which is a protective movement known as the nociceptive withdrawal response (NWR). The NWR has been previously studied in spinalized, decerebrated and anesthetized non-human and human mammals; however, there is minimal information on the NWR in intact, unanesthetized non-human mammals.

The first specific aim was to identify the factors that determine the direction and magnitude of the NWR in intact, unanesthetized rats. Based on previous studies, we hypothesized that the location of stimulation and the initial position of the paw preceding the NWR will influence the direction and magnitude ...


Po2 Dependence Of Oxygen Consumption In Skeletal Muscle Of Hypertensive And Normotensive Rats, Habiba Shah 2017 Virginia Commonwealth University

Po2 Dependence Of Oxygen Consumption In Skeletal Muscle Of Hypertensive And Normotensive Rats, Habiba Shah

Theses and Dissertations

Human essential hypertension affects over 75 million people in the United States, and can lead to death due to its several serious health complications such as hypertension-related cardiovascular disease. The purpose of this research was to understand how hypertension could cause physiological changes to the microcirculation, specifically the PO2 dependence of oxygen consumption (VO2) in skeletal muscle of normotensive and hypertensive rats. The Spontaneously Hypertensive Rat (SHR) strain was used as the diseased model, and Wistar-Kyoto (WKY) rats were used as controls to conduct this study. The SHR strain develops hypertension between 5-6 weeks after birth with an ...


Annotation And Identification Of Several Glycerolipid Metabolic Related Ortholog Genes; Mrub_0437, Mrub_1813 And Mrub_2759 In The Organism Meithermus Ruber And Their Predicted Respective Orthologs B3926, B4042 And Bo514 Found In E.Coli., Abdul Rahman Abdul Kader, Dr. Lori R. Scott 2017 Augustana College, Rock Island Illinois

Annotation And Identification Of Several Glycerolipid Metabolic Related Ortholog Genes; Mrub_0437, Mrub_1813 And Mrub_2759 In The Organism Meithermus Ruber And Their Predicted Respective Orthologs B3926, B4042 And Bo514 Found In E.Coli., Abdul Rahman Abdul Kader, Dr. Lori R. Scott

Meiothermus ruber Genome Analysis Project

We predict Mrub_0437 encodes the enzyme glycerol kinase (DNA coordinates [417621..419183), which is an intermediary step of the glycerolipid metabolic pathway (KEGG map00561), It catalyzes the conversion of glycerol to sn-Glycerol-3-phosphate. The E. coli K12 MG1655 ortholog is predicted to be b3926.

We predict Mrub_1813 encodes the enzyme diacylglycerol kinase (DNA coordinates [1864659..1865063), which is an intermediary step of the glycerolipid metabolic pathway (KEGG map00561), It catalyzes the conversion of 1,2-diacyl-sn-glycerol to 1,2-diacyl-sn-glycerol 3-phosphate. The E. coli K12 MG1655 ortholog is predicted to be b4042.

We predict Mrub_2759 encodes the enzyme glycerol kinase (DNA coordinates [2799712 ...


Mouth Exposure To Carbohydrate Prior To Exercise Possibly Impairs The Efficacy Of Carbohydrate Mouth Rinsing During Exercise, Kevin Decker 2017 James Madison University

Mouth Exposure To Carbohydrate Prior To Exercise Possibly Impairs The Efficacy Of Carbohydrate Mouth Rinsing During Exercise, Kevin Decker

Masters Theses

Decker K. P., M. J. Saunders, N. D. Luden, C. J. Womack, and N. J. Hladick. Mouth Exposure to Carbohydrate Prior to Exercise Possibly Impairs the Efficacy of Carbohydrate Mouth Rinsing during Exercise. Purpose: Carbohydrate mouth-rinsing (CHO-MR) during intense endurance exercise has been associated with improved cycling performance, due to neurological influences. However, prior studies have reported the efficacy of CHO-MR is attenuated following a pre-exercise meal. To determine if this outcome is related to desensitization of CHO receptors (rather than metabolic effects following digestion), this study will investigate whether CHO-MR prior to exercise influences cycling performance when CHO-MR is ...


Planaria: An Animal Model That Integrates Development, Regeneration And Pharmacology, Oné R. Pagán 2017 West Chester University of Pennsylvania

Planaria: An Animal Model That Integrates Development, Regeneration And Pharmacology, Oné R. Pagán

Biology Faculty Publications

Although planarians are established model organisms in developmental biology and regeneration studies, in the last forty years or so, they have caught the attention of pharmacologists, especially to study the pharmacology of drugs of abuse. This review covers the following topics: some fundamentals of the history of animal models and planarians in biomedical research; an abbreviated story of systematic pharmacology research using planarians as a model organism; an example of how planarians are contributing to the search for compounds against acute cocaine toxicity; an analysis of the number of papers on planarians and pharmacological topics from 1900- 2016; some perspectives ...


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