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Radiochemistry Commons

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Articles 1 - 30 of 263

Full-Text Articles in Radiochemistry

Transcriptional And Chemical Changes In Soybean Leaves In Response To Long-Term Aphid Colonization, Jessica D. Hohenstein, Matthew Studham, Adam Klein, Nik Kovinich, Kia Barry, Young-Jin Lee, Gustavo C. Macintosh Jun 2019

Transcriptional And Chemical Changes In Soybean Leaves In Response To Long-Term Aphid Colonization, Jessica D. Hohenstein, Matthew Studham, Adam Klein, Nik Kovinich, Kia Barry, Young-Jin Lee, Gustavo C. Macintosh

Gustavo Macintosh

Soybean aphids (Aphis glycines Matsumura) are specialized insects that feed on soybean (Glycine max) phloem sap. Transcriptome analyses have shown that resistant soybean plants mount a fast response that limits aphid feeding and population growth. Conversely, defense responses in susceptible plants are slower and it is hypothesized that aphids block effective defenses in the compatible interaction. Unlike other pests, aphids can colonize plants for long periods of time; yet the effect on the plant transcriptome after long-term aphid feeding has not been analyzed for any plant–aphid interaction. We analyzed the susceptible and resistant (Rag1) transcriptome response to aphid feeding ...


Isotopically-Resolved Neutron Cross Sections As Probe Of The Nuclear Optical Potential, Cole Davis Pruitt May 2019

Isotopically-Resolved Neutron Cross Sections As Probe Of The Nuclear Optical Potential, Cole Davis Pruitt

Arts & Sciences Electronic Theses and Dissertations

Neutron scattering experiments provide direct access to the forces experienced by nucleons in the nuclear environment. Due to the experimental difficulty of cross section measurements with neutrons, isotopically-resolved neutron scattering cross sections are sorely needed as inputs for many nuclear models. This dissertation presents the results from a campaign of isotope-specific neutron total cross section measurements on 16,18O, 58,64Ni, 112,124Sn, and 103Rh from 3-450 MeV and elastic scattering differential cross section measurements on 112,nat,124Sn at 11 and 17 MeV. Equipped with these new data and with computational improvements to the Dispersive Optical Model (DOM), we ...


Transcriptional And Chemical Changes In Soybean Leaves In Response To Long-Term Aphid Colonization, Jessica D. Hohenstein, Matthew Studham, Adam Klein, Nik Kovinich, Kia Barry, Young-Jin Lee, Gustavo C. Macintosh Mar 2019

Transcriptional And Chemical Changes In Soybean Leaves In Response To Long-Term Aphid Colonization, Jessica D. Hohenstein, Matthew Studham, Adam Klein, Nik Kovinich, Kia Barry, Young-Jin Lee, Gustavo C. Macintosh

Chemistry Publications

Soybean aphids (Aphis glycines Matsumura) are specialized insects that feed on soybean (Glycine max) phloem sap. Transcriptome analyses have shown that resistant soybean plants mount a fast response that limits aphid feeding and population growth. Conversely, defense responses in susceptible plants are slower and it is hypothesized that aphids block effective defenses in the compatible interaction. Unlike other pests, aphids can colonize plants for long periods of time; yet the effect on the plant transcriptome after long-term aphid feeding has not been analyzed for any plant–aphid interaction. We analyzed the susceptible and resistant (Rag1) transcriptome response to aphid feeding ...


Radium Dial Watches, Zainab Alzoubi Jan 2019

Radium Dial Watches, Zainab Alzoubi

Natural Sciences Poster Sessions

This slide presentation for the Natural Sciences Poster Session at Parkland College summarizes the history of radium dial watches, including the Radium Girls, and explores whether radium dial watches might still be dangerous.


Radiolabeled Nanohydroxyapatite As A Platform For The Development Of New Pet Imaging Agents, Stacy Lee Queern Dec 2018

Radiolabeled Nanohydroxyapatite As A Platform For The Development Of New Pet Imaging Agents, Stacy Lee Queern

Arts & Sciences Electronic Theses and Dissertations

Positron emission tomography (PET) imaging utilizes drugs labeled with positron emitters to target and evaluate different biological processes occurring in the body. Tailoring medicine to the individual allows for higher quality of care with better diagnosis and treatment and is a key purpose for advancing research into developing new platforms for PET imaging agents. A PET nuclide of high interest for the development of these agents is 89Zr. This can be attributed to the long half-life of 3.27 days and low positron energy of 89Zr.

In this work, we developed a production method for 89Zr using Y sputtered coins ...


Corrosion Dynamics Of Carbon Steel In Used Fuel Container Environments, Dan Guo Dec 2018

Corrosion Dynamics Of Carbon Steel In Used Fuel Container Environments, Dan Guo

Electronic Thesis and Dissertation Repository

The current Canadian used nuclear fuel container (UFC) design uses a pressure‑grade carbon steel (CS) vessel with its outer surface coated with a thin layer of copper. One concern regarding the structural integrity of the UFC design is the potential internal corrosion of the CS vessel. Moisture trapped inside a UFC could condense within the gap between the hemispherical head and the cylindrical body of the vessel. The internal UFC environment will be exposed to a continuous flux of ionizing radiation arising from the decay of radionuclides trapped in the used UO2 fuel matrix.

This thesis research project ...


Fundamental Chemistry Related To The Separations And Coordination Of Actinium-225, Thorium-227, And Technetium-99, Jasmine L. Hatcher Sep 2018

Fundamental Chemistry Related To The Separations And Coordination Of Actinium-225, Thorium-227, And Technetium-99, Jasmine L. Hatcher

All Dissertations, Theses, and Capstone Projects

This work explores the fundamental chemistry of actinium, thorium, and technetium in an effort to develop methodologies which help to address complications specific to each of these elements. Developing fundamental knowledge in inorganic chemistry has the power to meaningfully address a number of real world problems. By using simple systems and experiments like following an electron or changing the solvent system, we are able to gain invaluable information which can be used to address major issues.

Actinium-225 (t½: 9.92 d) is an alpha-emitting radionuclide with nuclear properties well suited for alpha therapy of malignant tumors. The present global ...


Spin Alignment Generated In Inelastic Nuclear Reactions, Daniel Hoff Aug 2018

Spin Alignment Generated In Inelastic Nuclear Reactions, Daniel Hoff

Arts & Sciences Electronic Theses and Dissertations

The spin alignment of inelastically excited 7Li projectiles, when the target remains in its ground state, was determined through angular-correlation measurements between the breakup fragments of 7Li_ (_ + t). It was found that 7Li_ is largely aligned along the beam axis (longitudinal) in this type of inelastic reaction, regardless of the target. This longitudinal alignment is well described by DWBA calculations, which can be explained by an angular-momentum-excitation-energy mismatch condition. These calculations also explain the longitudinal spin alignment of excited nuclei in several other systems, showing the phenomenon is more general. The experiment involving 7Li was performed at the Texas ...


Enhancing The Sensitivity Of Solid-State Nmr Experiments With Very Low Gyromagnetic Ratio Nuclei With Fast Magic Angle Spinning And Proton Detection, Amrit Venkatesh, Matthew J. Ryan, Abhranil Biswas, Kasuni C. Boteju, Aaron D. Sadow, Aaron J. Rossini Jul 2018

Enhancing The Sensitivity Of Solid-State Nmr Experiments With Very Low Gyromagnetic Ratio Nuclei With Fast Magic Angle Spinning And Proton Detection, Amrit Venkatesh, Matthew J. Ryan, Abhranil Biswas, Kasuni C. Boteju, Aaron D. Sadow, Aaron J. Rossini

Aaron D. Sadow

Many transition metals commonly encountered in inorganic materials and organometallic compounds possess NMR-active nuclei with very low gyromagnetic ratios (γ) such as 89Y, 103Rh, 109Ag, and 183W. A low-γ leads to poor NMR sensitivity and other experimental challenges. Consequently, nuclei with low-γ are often impossible to study with conventional solid-state NMR methods. Here, we combine fast magic angle spinning (MAS) and proton detection to enhance the sensitivity of solid-state NMR experiments with very low-γ nuclei by 1–2 orders of magnitude. Coherence transfer between 1H and low-γ nuclei was performed with low-power double quantum (DQ) or zero quantum (ZQ) cross-polarization ...


A System For Conducting Laser-Induced Fluorescence Measurements On Gas Mixtures Exposed To Alpha Radiation, Patrick Ables Jul 2018

A System For Conducting Laser-Induced Fluorescence Measurements On Gas Mixtures Exposed To Alpha Radiation, Patrick Ables

Master's Theses

This paper documents modifications to an existing vacuum system to allow laser-induced fluorescence spectroscopy measurements within simulated atmospheres under a variety of conditions. This added capability will expand the laboratory’s ability to experimentally validate a computational model that calculates the effects of radiation within the atmosphere. The computational model could reveal radiation-induced chemical products that can be used to develop an alternative detection method that can be implemented from a safe distance. The selection of molecules for experimental validation has been limited to those which can be detected utilizing cavity ringdown spectroscopy. The current model indicates nitric oxide and ...


Recommended Corrective Security Measures To Address The Weaknesses Identified Within The Shapash Nuclear Research Institute, Khadija Moussaid, Oum Keltoum Hakam Jun 2018

Recommended Corrective Security Measures To Address The Weaknesses Identified Within The Shapash Nuclear Research Institute, Khadija Moussaid, Oum Keltoum Hakam

International Journal of Nuclear Security

The Shapash Nuclear Research Institute (SNRI) data book was issued by the International Atomic Energy Agency (IAEA) in 2013. The hypothetical facility data book describes the hypothetical site, which is divided into two areas: the low-security area, known as the administrative area, and the very high-security area, known as the protected area. The book contains detailed descriptions of each area’s safety and security measures, along with figures of multiple buildings in both areas, and also includes information about the site’s computer networks.

This paper aims to identify security weaknesses related to the institute’s location, the Administrative Area ...


Enhancing The Sensitivity Of Solid-State Nmr Experiments With Very Low Gyromagnetic Ratio Nuclei With Fast Magic Angle Spinning And Proton Detection, Amrit Venkatesh, Matthew J. Ryan, Abhranil Biswas, Kasuni C. Boteju, Aaron D. Sadow, Aaron J. Rossini Jun 2018

Enhancing The Sensitivity Of Solid-State Nmr Experiments With Very Low Gyromagnetic Ratio Nuclei With Fast Magic Angle Spinning And Proton Detection, Amrit Venkatesh, Matthew J. Ryan, Abhranil Biswas, Kasuni C. Boteju, Aaron D. Sadow, Aaron J. Rossini

Ames Laboratory Accepted Manuscripts

Many transition metals commonly encountered in inorganic materials and organometallic compounds possess NMR-active nuclei with very low gyromagnetic ratios (γ) such as 89Y, 103Rh, 109Ag, and 183W. A low-γ leads to poor NMR sensitivity and other experimental challenges. Consequently, nuclei with low-γ are often impossible to study with conventional solid-state NMR methods. Here, we combine fast magic angle spinning (MAS) and proton detection to enhance the sensitivity of solid-state NMR experiments with very low-γ nuclei by 1–2 orders of magnitude. Coherence transfer between 1H and low-γ nuclei was performed with low-power double quantum (DQ) or zero quantum (ZQ) cross-polarization ...


Development Of Chemical Separation Methods Using Transition Metals For Nuclear Forensic And Medicinal Applications, Lucas Peter Boron-Brenner May 2018

Development Of Chemical Separation Methods Using Transition Metals For Nuclear Forensic And Medicinal Applications, Lucas Peter Boron-Brenner

UNLV Theses, Dissertations, Professional Papers, and Capstones

Insufficient data exists on the effects of prompt fast neutron activation on metals found commonly in nuclear devices and the urban environment. Different metals such as Ti, Au, Fe, and Cu were activated using the Flattop Criticality Benchmark at the Device Assembly Facility on the Nevada Test Site using a known neutron spectrum and flux to determine a baseline cross section value. Cross section information gathered from these neutron activation measurements could provide information that helps government and law enforcement agencies to correctly trace the origin of a nuclear device’s fuel or component features.

Based on activation products produced ...


Use Of Sodium Bismuthate Chromatography For Separation Of Americium From Curium And Other Elements In Spent Nuclear Fuel, Jason Michael Richards May 2018

Use Of Sodium Bismuthate Chromatography For Separation Of Americium From Curium And Other Elements In Spent Nuclear Fuel, Jason Michael Richards

UNLV Theses, Dissertations, Professional Papers, and Capstones

A novel method for partitioning americium from curium has been developed using sodium bismuthate as both an oxidant and a separation medium. The presence of americium and curium in nuclear waste increases the heat load in geological repositories and leads to larger waste volumes. These elements are also the source of most of the long-term radiotoxicity of the waste. However, the heat load and long-term radiotoxicity contribution from americium is much greater than that from curium. The contribution of curium to the heat load and radiotoxicity of the waste is significant on the same time scale as longer-lived fission products ...


Rapid Methods For Actinide And Strontium-89,90 Determination In Urban Matrices, Sherrod Maxwell May 2018

Rapid Methods For Actinide And Strontium-89,90 Determination In Urban Matrices, Sherrod Maxwell

UNLV Theses, Dissertations, Professional Papers, and Capstones

Rapid radiochemical methods are needed to provide fast, reliable analytical measurements on a variety of different sample matrices in the case of a radiological event to protect the public, mitigate dose and protect the environment. If a radiological dispersive device (RDD), an Improvised Nuclear Device (IND) or a nuclear accident occurs, there will be an urgent need for quick analyses of urban matrices materials to support decision-making, dose mitigation and environmental clean-up. Since an incident involving a RDD or IND will likely occur in an urban or metropolitan area, it is very important to employ swift, robust analytical methods that ...


Developing Kenya’S Educational Capacity In Nuclear Security Through Nuclear Forensics Research, Hudson Kalambuka Angeyo Apr 2018

Developing Kenya’S Educational Capacity In Nuclear Security Through Nuclear Forensics Research, Hudson Kalambuka Angeyo

International Journal of Nuclear Security

Nuclear energy’s distinctive characteristics give rise to special educational requirements. These requirements are necessary to not only address the danger of nuclear proliferation, but also to build capacity for a secure nuclear fuel circle. In this paper, I assess the status of educational capacity in nuclear security both in response to, and in support of, Kenya’s nuclear power program. I highlight the nuclear security educational infrastructure’s key features in the context of nuclear power, noting the low capacity at Kenyan universities. I identify the steps required to ensure that the country’s dynamic nuclear regulatory infrastructural framework ...


Revealing Individual Lifestyles Through Mass Spectrometry Imaging Of Chemical Compounds In Fingerprints, Paige Hinners, Kelly C. O’Neill, Young Jin Lee Mar 2018

Revealing Individual Lifestyles Through Mass Spectrometry Imaging Of Chemical Compounds In Fingerprints, Paige Hinners, Kelly C. O’Neill, Young Jin Lee

Chemistry Publications

Fingerprints, specifically the ridge details within the print, have long been used in forensic investigations for individual identification. Beyond the ridge detail, fingerprints contain useful chemical information. The study of fingerprint chemical information has become of interest, especially with mass spectrometry imaging technologies. Mass spectrometry imaging visualizes the spatial relationship of each compound detected, allowing ridge detail and chemical information in a single analysis. In this work, a range of exogenous fingerprint compounds that may reveal a personal lifestyle were studied using matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI). Studied chemical compounds include various brands of bug sprays and ...


Improving Fallout Characterization By Using Multivariate Techniques To Determine Composition, Christopher R. Pitkins Mar 2018

Improving Fallout Characterization By Using Multivariate Techniques To Determine Composition, Christopher R. Pitkins

Theses and Dissertations

Multivariate statistical techniques have been applied in order to un-mix nuclear fallout debris chemical data. This information is critical to characterization of fallout particle formation following a nuclear detonation. Understanding the correlation between environmental precursors and actinide concentrations in post-detonation nuclear fallout material aids in understanding the physical and chemical processes that alter nuclear device signatures in the fireball. This research examines 123 nuclear fallout samples from a historical nuclear test. Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) are used to collect chemical compositions of the fallout samples. Principal component analysis (PCA) is applied in order to examine ...


The "Double Standard" Of Nonproliferation: Regime Type And The U.S. Response To Nuclear Weapons Program, Alina Shymanska Mar 2018

The "Double Standard" Of Nonproliferation: Regime Type And The U.S. Response To Nuclear Weapons Program, Alina Shymanska

International Journal of Nuclear Security

There is no doubt that the NPT regime is far from being equal for all states involved. As the predominant hegemonic power since WWII, the United States plays a major role in deciding the fates of non-great power proliferators. This article tries to find the logical explanation of the phenomenon whereby some nuclear proliferators are absolved regardless of their active accumulation of nuclear arsenals while others are labeled as “rogue states” and ordered to disarm. The article suggests that a particular proliferator’s political regime could affect the way in which its state is approached by the U.S., known ...


Quantitative Atomic-Scale Structure Characterization Of Ordered Mesoporous Carbon Materials By Solid State Nmr, Zhuoran Wang, Naftali Opembe, Takeshi Kobayashi, Nicholas C. Nelson, Igor I. Slowing, Marek Pruski Jan 2018

Quantitative Atomic-Scale Structure Characterization Of Ordered Mesoporous Carbon Materials By Solid State Nmr, Zhuoran Wang, Naftali Opembe, Takeshi Kobayashi, Nicholas C. Nelson, Igor I. Slowing, Marek Pruski

Chemistry Publications

Solid-state (SS)NMR techniques were applied to characterize the atomic-scale structures of ordered mesoporous carbon (OMC) materials prepared using Pluronic F127 as template with resorcinol and formaldehyde as polymerizing precursors. A rigorous quantitative analysis was developed using a combination of 13C SSNMR spectra acquired with direct polarization and cross polarization on natural abundant and selectively 13C-enriched series of samples pyrolyzed at various temperatures. These experiments identified and counted the key functional groups present in the OMCs at various stages of preparation and thermal treatment. The chemical evolution of molecular networks, the average sizes of aromatic clusters and the ...


The Molecular Basis Of Caspase-9 Inactivation By Pka And C-Abl Kinases, Banyuhay Paningbatan Serrano Jan 2018

The Molecular Basis Of Caspase-9 Inactivation By Pka And C-Abl Kinases, Banyuhay Paningbatan Serrano

Doctoral Dissertations

Caspases are the cysteine proteases that facilitate the fundamental pathway of programmed cell death or apoptosis. The activation and function of these powerful enzymes are tightly regulated to ensure the faithful execution of apoptosis and prevent untimely cell death. Many deadly human diseases such as cancer, neurodegeneration and autoimmune disorders have been associated with defective activation and faulty regulation of caspases. As such, caspases are considered as attractive drug targets, which when properly controlled, can lead to effective therapeutics for apoptosis-related diseases. Thus, comprehensive investigations of the structure, function and regulation of caspases are necessary to understand the complex mechanisms ...


Assessing And Enhancing Nuclear Safety And Security Culture For Small Facilities That Handle Radioactive Material, Solymosi Máté Dec 2017

Assessing And Enhancing Nuclear Safety And Security Culture For Small Facilities That Handle Radioactive Material, Solymosi Máté

International Journal of Nuclear Security

The use of radioactive sources is expanding all over the world and abreast the necessity of the enhancement of its safe and secure application is increasing too. In the nuclear industry, the safety and security are top priorities since decades. They share the same goal, to protect humans from the negative affect of the ionizing radiation. The human component of them is a significant factor and technical solutions can protect us so far and thus the culture for safety and security become a major focus. On the other hand, there are still some contradiction between recommendations and international guidance of ...


The Future Of Nuclear Security In Moroccan Territory After The Creation Of The New Moroccan Agency Of Nuclear And Radiological Safety And Security: Opportunities And Challenges, Amal Touarsi, Amina Kharchaf Dec 2017

The Future Of Nuclear Security In Moroccan Territory After The Creation Of The New Moroccan Agency Of Nuclear And Radiological Safety And Security: Opportunities And Challenges, Amal Touarsi, Amina Kharchaf

International Journal of Nuclear Security

Nowadays, a security regime for protecting nuclear and radiological material—providing an intelligent national regulatory institution and establishing national security laws—is necessary in order for a state to ensure security of nuclear and radiological materials used within its borders.

This paper focuses on discussing the opportunities and challenges facing the future of nuclear security after the creation of the new Moroccan Agency of Nuclear and Radiological Safety and Security.


Solar System Battery Backups For Reactor Coolant Pumps During Electricity Outages Resulting From Natural Disasters, Md. Shamsul Huda Sohel Nov 2017

Solar System Battery Backups For Reactor Coolant Pumps During Electricity Outages Resulting From Natural Disasters, Md. Shamsul Huda Sohel

International Journal of Nuclear Security

In a nuclear power plant, its coolant system is major safety equipment. Coolant system failure causes several accidents in nuclear history. There are so many causes for coolant system failure. One of them is lack of electric power for coolant pumps. In typically NPP there is backup system for power redundancy. In this article, focus on reactor coolant system and its backup power when main grid lines failure. Here discuss about solar backup power for batteries and increases a safety lines for reactor coolant pumps. So, our main goal is providing a battery backup from reliable natural source and ensuring ...


Gamma-Radiation Induced Corrosion Of Alloy 800, Mojtaba Momeni Nov 2017

Gamma-Radiation Induced Corrosion Of Alloy 800, Mojtaba Momeni

Electronic Thesis and Dissertation Repository

This thesis presents a newly developed mechanism and predictive model for the corrosion of Alloy 800. The Fe-Cr-Ni Alloy (Incoloy 800) is mainly used for steam generator (SG) tubing in CANDU and PWR reactors and is a candidate material for the proposed Canadian Supercritical Water Reactor (SCWR) in which it will be exposed to extreme conditions of high radiation flux and large temperature gradients. The influence of gamma radiation and water chemistry conditions on the corrosion behaviour of Alloy 800 are studied in this work. Ionizing radiation creates reducing (•eaq, •H, •O2-) and oxidizing radiolysis (•OH, H2 ...


3d Maldi Mass Spectrometry Imaging Of A Single Cell: Spatial Mapping Of Lipids In The Embryonic Development Of Zebrafish, Maria Emilia Dueñas, Jeffrey J. Essner, Young Jin Lee Nov 2017

3d Maldi Mass Spectrometry Imaging Of A Single Cell: Spatial Mapping Of Lipids In The Embryonic Development Of Zebrafish, Maria Emilia Dueñas, Jeffrey J. Essner, Young Jin Lee

Ames Laboratory Accepted Manuscripts

The zebrafish ( Danio rerio ) has been widely used as a model vertebrate system to study lipid metabolism, the roles of lipids in diseases, and lipid dynamics in embryonic development. Here, we applied high-spatial resolution matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry imaging (MSI) to map and visualize the three-dimensional spatial distribution of phospholipid classes, phosphatidylcholine (PC), phosphatidylethanolamines (PE), and phosphatidylinositol (PI), in newly fertilized individual zebrafish embryos. This is the first time MALDI-MSI has been applied for three dimensional chemical imaging of a single cell. PC molecular species are present inside the yolk in addition to the blastodisc, while PE ...


High-Throughput Selective Capture Of Single Circulating Tumor Cells By Dielectrophoresis At A Wireless Electrode Array, Robbyn Anand, Min Li Jun 2017

High-Throughput Selective Capture Of Single Circulating Tumor Cells By Dielectrophoresis At A Wireless Electrode Array, Robbyn Anand, Min Li

Chemistry Publications

We demonstrate continuous high-throughput selective capture of circulating tumor cells by dielectrophoresis at arrays of wireless electrodes (bipolar electrodes, BPEs). The use of BPEs removes the requirement of ohmic contact to individual array elements, thus enabling otherwise unattainable device formats. Capacitive charging of the electrical double layer at opposing ends of each BPE allows an AC electric field to be transmitted across the entire device. Here, two such designs are described and evaluated. In the first design, BPEs interconnect parallel microchannels. Pockets extruding from either side of the microchannels volumetrically control the number of cells captured at each BPE tip ...


Evolution Of Cu2o Morphology During Copper Corrosion In The Presence Of Gamma-Radiation, Arielle M. Jean Jun 2017

Evolution Of Cu2o Morphology During Copper Corrosion In The Presence Of Gamma-Radiation, Arielle M. Jean

Electronic Thesis and Dissertation Repository

In this work, experiments were carried out in order to develop a mechanistic understanding of the corrosion of copper metal in limited water volumes under gamma-radiation. When exposed to gamma-radiation, water decomposes into chemically reactive oxidizing and reducing species. Under a continuous radiation flux, the concentrations of the radiolytically produced oxidants eventually reach a pseudo-steady state that can influence the corrosion kinetics of metallic surfaces.

The evolution of the surface morphology during water droplet corrosion of copper in the presence of gamma-radiation was investigated as a function of irradiation time and pH. The oxide growth kinetics were studied by measuring ...


Chelating Ligands And Nanomaterials Based On Graphene Oxide For The Reduction And Sequestration Of Radiometals And Protein Purification, Sam Groveman Jun 2017

Chelating Ligands And Nanomaterials Based On Graphene Oxide For The Reduction And Sequestration Of Radiometals And Protein Purification, Sam Groveman

All Dissertations, Theses, and Capstone Projects

Nuclear waste remediation and protein purification using immobilized metals can benefit enormously from the design and implementation of novel chelating nanomaterials. Available commercial resins capable of sequestering metals are based on bulk materials such as organic polymers, ceramics, and their composites. The use of two-dimensional nanoplatforms with large surface areas expands the horizon for the research and development of new systems with higher efficiency and lower cost. Fundamental science challenges remain in the synthesis and characterization of these nanomaterials and their integration with known or novel coordinating ligands.

Chemical exfoliation of graphite under strong oxidizing conditions yields graphene oxide (GO ...


Development Of Neurotensin-Based Radiopharmaceuticals For Neurotensin-Receptor-1-Positive Tumors Targeting, Yinnong Jia May 2017

Development Of Neurotensin-Based Radiopharmaceuticals For Neurotensin-Receptor-1-Positive Tumors Targeting, Yinnong Jia

Theses & Dissertations

The neurotensin receptor 1 (NTR1) is overexpressed in many cancers, due to its role as a growth pathway. These NTR1-positive cancers include pancreatic, colon, prostate and breast cancers. In the radiopharmaceutical field, the overexpression of NTR1 in cancer has prompted the development of NTR1-targeted diagnostics and therapeutics. The neurotensin (NT) peptide exhibits low nanomolar affinity for NTR1 and has been the paradigm for NTR1-targeted agents. Since the 1980’s, radiolabeled NT analogs have been developed and evaluated for targeting NTR1-positive cancers. Since native NT is rapidly degraded in vivo by a variety of peptidases, a tremendous amount of effort has ...