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2003

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Articles 1 - 30 of 35

Full-Text Articles in Organic Chemistry

Mechanistic Studies Of The Oxidation Of Lignin And Cellulose Models, Oh-Kyu Lee Dec 2003

Mechanistic Studies Of The Oxidation Of Lignin And Cellulose Models, Oh-Kyu Lee

Electronic Theses and Dissertations

Oxygen delignification is an environmentally friendly pulp bleaching system. To develop a selective delignification process that results in high DP retention of carbohydrate with lignin being removed, obtaining better knowledge of reactions occurring during oxygen delignification is essential.

In this work, mixtures of guaiacol (model lignin) and methyl-ß-D-glucoside (model cellulose) were reacted in a pressurized oxygen reaction system (pH 12,65 psi O2, and 95°C in a glass reaction vessel). In the results, methyl-ß-D-glucoside degraded only in the presence of lignin. This indicates that hydroxyl radicals, that subsequently react with methyl-ß-D-glucoside, are generated in the system. Unfortunately, we ...


Effects Of Fiberimatiux Interactions On The Interfacial Deformation Micromechanics Of Cellulose-Fiberipolymer Composites, William Tai-Yin Tze Aug 2003

Effects Of Fiberimatiux Interactions On The Interfacial Deformation Micromechanics Of Cellulose-Fiberipolymer Composites, William Tai-Yin Tze

Electronic Theses and Dissertations

The overall objective of this dissertation was to gain an understanding of the relationship between interfacial chemistry and the micromechanics of the cellulose-fiber/polymer composites. Regenerated cellulose (lyocell) fibers were treated with amine-, phenylamine-, phenyl-, and octadecyl-silanes, and also styrene-maleic anhydride copolymer. Inverse gas chromatography was conducted to evaluate the modified surfaces and to examine the adsorption behavior of ethylbenzene, a model compound for polystyrene, onto the fibers. Micro-composites were formed by depositing micro-droplets of polystyrene onto single fibers. The fiber was subjected to a tensile strain, and Raman spectroscopy was employed to determine the point-to-point variation of the strain- ...


A Direct Synthesis Of O-Methyl Claussequinone, George A. Kraus, Ikyon Kim May 2003

A Direct Synthesis Of O-Methyl Claussequinone, George A. Kraus, Ikyon Kim

Chemistry Publications

The reaction of a chromene with BH3 followed by treatment with benzoquinone and air is the key step in a direct entry to O-methyl claussequinone.


Synthesis Of Novel [3, 2-B] Indole Fused Oleanolic Acids As Potential Inhibitors Of Cell Proliferation, Heather J. Finlay, Tadashi Honda, Gordon W. Gribble May 2003

Synthesis Of Novel [3, 2-B] Indole Fused Oleanolic Acids As Potential Inhibitors Of Cell Proliferation, Heather J. Finlay, Tadashi Honda, Gordon W. Gribble

Open Dartmouth: Faculty Open Access Scholarship

Seven new indole-fused oleanolic acid derivatives were synthesized from oleanolic acid for their ability to inhibit cell proliferation in NRP. 152 cells.


Oxygen Delignification Kinetics And Selectivity Improvement, Steven M. Violette May 2003

Oxygen Delignification Kinetics And Selectivity Improvement, Steven M. Violette

Electronic Theses and Dissertations

Pulp strength loss during oxygen delignification is caused by cellulose chain cleavage resulting fiom attack by oxygen-based radicals generated through reactions with lignin. The objective of this research was to improve the lignin-to-cellulose selectivity during oxygen delignification by using radical-scavenging polymeric additives that adsorb on the cellulose surfaces where protection fiom radicals is needed. Among the polymers evaluated were starch, carboxymethyl-cellulose, galactomannan, xylan, and glucomannan. Oxygen delignification experiments were conducted on Northeast softwood Kraft pulps at different temperatures, sodium hydroxide charges, reaction times, and pretreatments. The effect of polymer additives on the selectivity and kinetics was studied. Polymer adsorption on ...


Relationship Between Alkaline Pulp Yield And The Mass Fraction And Degree Of Polymerization Of Cellulose In Pulp, Mehmet Sefik Tunc May 2003

Relationship Between Alkaline Pulp Yield And The Mass Fraction And Degree Of Polymerization Of Cellulose In Pulp, Mehmet Sefik Tunc

Electronic Theses and Dissertations

Wood as a raw material is generally the dominant cost factor for the production of chemical pulp. Therefore, an increase in pulp yield has a major impact on the competitiveness of a mill. In order to optimize pulp yield, for example by changing operating conditions, a mill must be able to monitor the yield accurately. However, an accurate "real-time" pulp yield measurement method is not available at the present time. Pulping yield is presently measured from the amount of pulp produced from a given quantity of wood consumed over a 3 to 6 month time frame. This method is obviously ...


Three-Dimensional Quantitative Structure−Property Relationship (3d-Qspr) Models For Prediction Of Thermodynamic Properties Of Polychlorinated Biphenyls (Pcbs): Enthalpies Of Fusion And Their Application To Estimates Of Enthalpies Of Sublimation And Aqueous Solubilities, Swati Puri, James S. Chickos, William J. Welsh Apr 2003

Three-Dimensional Quantitative Structure−Property Relationship (3d-Qspr) Models For Prediction Of Thermodynamic Properties Of Polychlorinated Biphenyls (Pcbs): Enthalpies Of Fusion And Their Application To Estimates Of Enthalpies Of Sublimation And Aqueous Solubilities, Swati Puri, James S. Chickos, William J. Welsh

James Chickos

No abstract provided.


E Z Stereoisomerization In Methylene Bis-Dithiocarbamate And N,N,S Trimethyldithiocarbamate, Caroline Pharr, John Thorburn Apr 2003

E Z Stereoisomerization In Methylene Bis-Dithiocarbamate And N,N,S Trimethyldithiocarbamate, Caroline Pharr, John Thorburn

Chemistry and Physics Undergraduate Theses

Rates of rotation about the carbon-nitrogen partial double bond in N,N,Strimethyldithiocarbamate (1) and methylene bis-dithiocarbamate (2) were measured by the dynamic NMR technique known as selective inversion recovery. Free energies of activation (AG*) for the rotational barrier about the carbon-nitrogen partial double bond in compounds 1 and 2 were determined in a variety of solvents. Compound 1 was found to have a lower rotational barrier than compound 2. As solvent polarity increased, an increase in rotational barrier was observed. Contrary to expectations, hydroxylic solvents lowered the rotational barrier for compounds 1 and 2 based on their increased solvent ...


Synthetic Approach To Malibatol  A, George A. Kraus, Ikyon Kim Mar 2003

Synthetic Approach To Malibatol  A, George A. Kraus, Ikyon Kim

Chemistry Publications

A synthetic approach to malibatol A featuring a novel benzofuran synthesis is described.


Heat Capacities Of Thiane Sulfones And Thiane Sulfoxide: Refining Of Cp Group Values For Organosulfur Compounds And Their Oxides, Marı́A Victoria Roux, Manuel Temprado, Pilar Jiménez, Ramón Guzmán-Mejı́A, Eusebio Juaristi, James S. Chickos Jan 2003

Heat Capacities Of Thiane Sulfones And Thiane Sulfoxide: Refining Of Cp Group Values For Organosulfur Compounds And Their Oxides, Marı́A Victoria Roux, Manuel Temprado, Pilar Jiménez, Ramón Guzmán-Mejı́A, Eusebio Juaristi, James S. Chickos

James Chickos

No abstract provided.


On The Existence And Stability Of Liquid Water On The Martian Surface, Justin Thompson Jan 2003

On The Existence And Stability Of Liquid Water On The Martian Surface, Justin Thompson

Inquiry: The University of Arkansas Undergraduate Research Journal

Present-day Mars is thought to be a frozen desert on which liquid water is not likely to be found. The prevailing assumption has been that due to average temperatures below 273 K and atmospheric pressures at or below water's triple-point vapor pressure of 6.1 mbar, the existence of liquid water as an equilibrium phase at or near the surface is impossible at the present epoch. However, there is substantial evidence that liquid water has existed in the past and may presently still exist on or directly below the Martian surface. I conducted simulation experiments in the Andromeda planetary ...


Advances In C-H Activation By Palladium: Migration And Cyclocarbonylation , Marino Andres Campo Molina Jan 2003

Advances In C-H Activation By Palladium: Migration And Cyclocarbonylation , Marino Andres Campo Molina

Retrospective Theses and Dissertations

Palladium-catalyzed intramolecular C-H activation of o-halobiaryls has been used to carry out important chemical transformations. For instance, in the presence of catalytic amounts of Pd(0), o-halobiaryls are readily cyclocarbonylated under an atmosphere of CO to produce fluorenones in high yields with good regioselectivity. This methodology has been successfully applied to the preparation of polycyclic fluorenones and fluorenones containing fused isoquinoline, indole, pyrrole, thiophene, benzothiophene, and benzofuran rings.;A novel 1,4-Pd migration between the o- and o'-positions of biaryls has been observed in organopalladium intermediates derived from o-halobiaryls. The organopalladium intermediates generated by this unique C-H activation-migration process ...


Bismuth Compounds In Organic Synthesis. Synthesis Of Resorcinarenes Using Bismuth Triflate, Ram Mohan, Katherine Peterson, Russell Smith Jan 2003

Bismuth Compounds In Organic Synthesis. Synthesis Of Resorcinarenes Using Bismuth Triflate, Ram Mohan, Katherine Peterson, Russell Smith

Scholarship

Bismuth triflate (5 mol%) smoothly catalyzes the condensation of aromatic and aliphatic aldehydes with resorcinol to give tetrameric cyclic products, resorcinarenes. With benzaldehyde, the product is obtained as a mixture of two diastereomers and the ratio of the diastereomers depends on reaction time. On the other hand, a single diastereomer is obtained with aliphatic aldehydes. The low toxicity and ease of handling of bismuth compounds coupled with fast reaction times make this method an attractive alternative to the existing methods for resorcinarene formation


Bismuth Compounds In Organic Synthesis. Deprotection Of Ketoximes Using Bismuth Bromide-Bismuth Triflate, Ram Mohan, Joshua Arnold, Patrick Hayes, Robert Kohaus Jan 2003

Bismuth Compounds In Organic Synthesis. Deprotection Of Ketoximes Using Bismuth Bromide-Bismuth Triflate, Ram Mohan, Joshua Arnold, Patrick Hayes, Robert Kohaus

Scholarship

Ketoximes undergo deprotection in CH3CN/acetone/H2O (3:6:1) in the presence of 20–40 mol% BiBr3/5 mol% Bi(OTf)3. Bismuth(III) salts are relatively non-toxic, insensitive to air and inexpensive. These features coupled with the use of a relatively non-toxic solvent system make this method an attractive alternative to existing routes for deprotection of ketoximes.


Nitroalkane Anomaly: Computational Study With Cluster And Continuum Modeling, H. Yamataka, Salai Cheettu Ammal Jan 2003

Nitroalkane Anomaly: Computational Study With Cluster And Continuum Modeling, H. Yamataka, Salai Cheettu Ammal

Faculty Publications

The origin of anomalous relation between rates and equilibria for the proton-transfer reactions of nitroalkanes, known as nitroalkane anomaly, was investigated by theoretical calculations with a cluster model, in which three water molecules are explicitly considered in the system, as well as the PCM solvent continuum model. For the CH3NO2/CH3CH2NO2 system, B3LYP and MP2 computations reproduced the anomaly, and the imbalance in the charge distribution at the transition state (TS) was observed. In contrast, although the TS imbalance was detected for the substituted phenylnitromethane system, the Brønsted plots did not show any anomaly. The experimentally observed abnormally large Brønsted ...


Direct Approaches To Natural Product Synthesis , Ikyon Kim Jan 2003

Direct Approaches To Natural Product Synthesis , Ikyon Kim

Retrospective Theses and Dissertations

In this dissertation, we have investigated direct routes to several biologically important natural products.;Chapter 1 describes a concise construction of core skeleton of malibatol A, employing a novel benzofuran formation methodology and a regio- and stereoselective 7-membered ring formation via Lewis acid catalyzed epoxide ring opening as crucial steps.;Chapter 2 describes direct approaches to isoflavanquinones utilizing radical addition to quinones. Three main strategies were presented and were compared to generate radicals from the corresponding precursors.;Chapter 3 describes a direct entry to erogorgiaene, naturally occurring potent antitubercular agent, featuring a regioselective metal-halogen exchange and a 6-exo-trig radical cyclization ...


Organogermanium Chemistry: Germacyclobutanes And Digermane Additions To Acetylenes , Andrew Michael Chubb Jan 2003

Organogermanium Chemistry: Germacyclobutanes And Digermane Additions To Acetylenes , Andrew Michael Chubb

Retrospective Theses and Dissertations

This dissertation comprises two main research projects. The first project, presented in Chapter 1, involves the synthesis and thermochemistry of germacyclobutanes (germetanes). Four new germetanes (spirodigermetane, diallylgermetane, dichlorogermetane, and germacyclobutane) have been synthesized using a modified di-Grignard synthesis. Diallylgermetane is shown to be a useful starting material for obtaining other germetanes, particularly the parent germetane, germacyclobutane. The gas-phase thermochemistries of spirodigermetane, diallylgermetane and germacyclobutane have been explored via pulsed stirred-flow reactor (SFR) studies, showing remarkable differences in decomposition, depending on the substitution at the germanium atom.;The second project investigates the thermochemical, photochemical, and catalytic additions of several digermanes to ...


New Palladium-Catalyzed Approaches To Heterocycles And Carbocycles, Guangxiu Dai Jan 2003

New Palladium-Catalyzed Approaches To Heterocycles And Carbocycles, Guangxiu Dai

Retrospective Theses and Dissertations

A wide variety of 3,4-disubstituted isoquinolines containing an aryl, allylic, benzylic, alkynyl and vinylic group at the 4 position have been prepared via cross-coupling of 2-(1-alkynyl)benzaldimines with organic halides in the presence of a palladium catalyst. The best results are obtained by employing 5 mol% Pd(PPh3)4, 5 equiv of K2CO 3 in DMF at 100°C. The electronic effect of the imine substrates and organic halides on the yields has been discussed.;3-Substituted 4-aroylisoquinolines have been prepared in high yields via carbonylative cross-coupling of 2-(1-alkynyl)benzaldimines with aromatic iodides or aroyl chlorides in the ...


Group 4 Metalloporphyrin Diolato Complexes And Catalytic Application Of Metalloporphyrins And Related Transition Metal Complexes , Guodong Du Jan 2003

Group 4 Metalloporphyrin Diolato Complexes And Catalytic Application Of Metalloporphyrins And Related Transition Metal Complexes , Guodong Du

Retrospective Theses and Dissertations

In this work, the first examples of group 4 metalloporphyrin 1,2-diolato complexes were synthesized through a number of strategies. In general, treatment of imido metalloporphyrin complexes, (TTP)M=NR, (M = Ti, Zr, Hf), with vicinal diols led to the formation of a series of diolato complexes. Alternatively, the chelating pinacolate complexes could be prepared by metathesis of (TTP)MCl 2 (M = Ti, Hf) with disodium pinacolate. These complexes were found to undergo C-C cleavage reactions to produce organic carbonyl compounds.;For titanium porphyrins, treatment of a titanium(II) alkyne adduct, (TTP)Ti(eta 2-PhC≡CPh), with aromatic aldehydes or ...


Thermally Induced Intramolecular Hydrogen Atom Transfer And The Study Of The Flash Vacuum Pyrolysis Of Various Cyclic And Non-Cyclic Organic Molecules Related To, And Including, O-Allyltoluene , Arthur Bruno Ferruzzi Jan 2003

Thermally Induced Intramolecular Hydrogen Atom Transfer And The Study Of The Flash Vacuum Pyrolysis Of Various Cyclic And Non-Cyclic Organic Molecules Related To, And Including, O-Allyltoluene , Arthur Bruno Ferruzzi

Retrospective Theses and Dissertations

In the course of studying the flash vacuum pyrolysis (FVP) of tetralin, workers in the Trahanovsky group have observed evidence of the secondary pyrolysis of o-allyltoluene. Further studies on the FVP of o-allyltoluene yielded evidence consistent with a rearrangement involving diradicals formed by an uncommon thermally induced intramolecular hydrogen-atom transfer. To investigate the scope of this rearrangement, we have studied the FVP's of several related alkylaryl olefins including o-allyltoluene-alpha,alpha,alpha- d3, (E/Z)-o-(1-propenyl)toluene, o-(1-methylallyl)toluene, o-allylethylbenzene, o-allylcumene, o-(3-butenyl)toluene, o-(4-butenyl)toluene, and 2-methylstyrene. Parallel studies on the phenol and aniline analogs of ...


Functionalized Materials From Elastomers To High Performance Thermoplastics , Laura Ann Salazar Jan 2003

Functionalized Materials From Elastomers To High Performance Thermoplastics , Laura Ann Salazar

Retrospective Theses and Dissertations

The development of functionalized materials has been achieved by the use of two different methods. The first method utilized a functional monomer that was subsequently polymerized to give the desired material. The second approach was a post-polymerization technique that allowed functionalization after the polymer was synthesized.;Functionalized monomers have the advantage of direct application after polymerization. Butadiene-based monomers have been chosen for their potential use in industrial systems. The chosen monomer, 2-(N-piperidylmethyl)-1,3-butadiene, contains a tertiary amine. This amine moiety has many potential applications in the areas of water treatment, biological applications, adhesives and sealants. Bulk free radical ...


Studies Of Immobilized Homogeneous Metal Catalysts On Silica Supports , Keith James Stanger Jan 2003

Studies Of Immobilized Homogeneous Metal Catalysts On Silica Supports , Keith James Stanger

Retrospective Theses and Dissertations

Rhodium complexes of the chiral, chelating diphosphine (2S,4S)-4-(diphenylphosphino)-2-(diphenylphosphinomethyl)pyrrolidine tethered on silica were characterized by 31P NMR and IR. The tethered complex catalyzes the enantioselective hydrogenation of methyl-alpha-acetamidocinnamate (MAC). Spectral and catalytic investigations indicate that the tethered complex reacts by the same mechanism as the untethered complex in solution.;The rhodium complexes, [Rh(COD)H]4, [Rh(COD)2] +BF4-, [Rh(COD)Cl]2, and RhCl3·3H2O, adsorbed on SiO2 are optimally activated for toluene hydrogenation by pretreatment with H2 at 200°C. The same complexes on Pd-SiO2 are equally active without pretreatments. The active ...


Deep Desulfurization Of Petroleum Feedstocks By Selective Adsorption And Extraction , Scott Groh Mckinley Jan 2003

Deep Desulfurization Of Petroleum Feedstocks By Selective Adsorption And Extraction , Scott Groh Mckinley

Retrospective Theses and Dissertations

The ability of Ru(NH3)5(H2O) 2+ to bind to thiophenes has been used in an extraction process in which a solution of Ru(NH3)5(H2O) 2+ in 70% DMF and 30% H2O is contacted with a simulated petroleum feedstock (45% toluene/55% hexanes) containing 400 ppm of DBT. Five successive extractions reduce the amount of DBT in the simulated feedstock from 400 ppm to 25 ppm. The Ru(NH3)5(H2O) 2+ extractant can be regenerated from the Ru(NH3) 5(DBT)2+ either by air-oxidation followed by H2-reduction or by displacement of the DBT by adding ...


Synthesis Of Polycyclic Natural Products , Tuan Hoang Nguyen Jan 2003

Synthesis Of Polycyclic Natural Products , Tuan Hoang Nguyen

Retrospective Theses and Dissertations

Highly oxidized polycyclic natural products are abundant in nature and have diverse biological activities. Hyperforin has been identified as the sole constituent responsible for the antidepressant characteristic of St. John's wort. An approach to an oxidized bicyclic phloroglucin core of hyperforin is described. Puupehenone, a sesquiterpene found in marine sponges, has recently emerged as a strong candidate to treat tuberculosis. The synthesis of the BCD rings of puupehenone containing a quinone methide moiety is described.


Palladium Approaches To Beta- And Gamma-Carbolines , Haiming Zhang Jan 2003

Palladium Approaches To Beta- And Gamma-Carbolines , Haiming Zhang

Retrospective Theses and Dissertations

A variety of substituted beta- and gamma-carbolines containing aryl, alkyl, hydroxymethyl, ester and silyl functionality at the 3- and 4-positions have been prepared by the palladium-catalyzed iminoannulation of internal and terminal alkynes. This methodology has been successfully employed to the synthesis of two biologically active beta-carboline alkaloids, ZK93423 and abecarnil.;A variety of 3-substituted beta- and gamma-carbolines have been synthesized from N-substituted 3-iodo-1H-indole-2-carboxaldehydes and 2-bromo-1H-indole-3-carboxaldehydes, respectively. The coupling of these aldehydes with various terminal acetylenes using cat. PdCl 2(PPh3)2/CuI readily affords the corresponding alkynylindole carboxaldehydes, which have subsequently been converted to the corresponding tert-butylimines and cyclized to ...


A Solvent-Free Oxidation Of Alcohols In An Organic Laboratory, John J. Esteb, Michael W. Schelle, Anne N. Wilson Jan 2003

A Solvent-Free Oxidation Of Alcohols In An Organic Laboratory, John J. Esteb, Michael W. Schelle, Anne N. Wilson

Scholarship and Professional Work - LAS

An oxidation experiment for a first-year organic chemistry class is presented. This oxidation utilizes a solid mixture of CuSO4•5H2O and KMnO4 prepared by mortar and pestle. The oxidations take place under solvent-free conditions and near quantitative yields are obtained for the reactions. Thin-layer chromatography is used to monitor the progress of the reaction. This experiment provides for the simple oxidation of a secondary alcohol to a ketone using a relatively nontoxic oxidizing agent under solvent-free conditions.


A Solvent-Free Claisen Condensation Reaction For The Organic Laboratory, John J. Esteb, Matthew B. Stockton Jan 2003

A Solvent-Free Claisen Condensation Reaction For The Organic Laboratory, John J. Esteb, Matthew B. Stockton

Scholarship and Professional Work - LAS

An experiment involving the Claisen condensation reaction for a first-year organic chemistry laboratory is presented. Claisen condensations are routinely covered in organic textbooks but owing to the long reaction times required to reach equilibrium in solution they are seldom explored in the undergraduate teaching laboratory. In this experiment, potassium tert-butoxide and ethyl phenylacetate are heated to 100 °C for 30 minutes under solvent-free conditions to produce 2,4-diphenyl acetoacetate in 80% yield. The solvent-free nature of this procedure greatly reduces the quantity of waste generated by students relative to typical carbonyl condensation experiments.


Synthetic And Mechanistic Studies Of Poly(Vinyl Chloride) And Some Other Chlorinated Polymers, Xianlong Ge Jan 2003

Synthetic And Mechanistic Studies Of Poly(Vinyl Chloride) And Some Other Chlorinated Polymers, Xianlong Ge

Dissertations, Theses, and Masters Projects

Unlike vinyl chloride, 1,2-dichloroethylene (DCE) experienced dimerization under free-radical conditions. Chain transfer to DCE by beta-Cl elimination was shown to be the major reason for its nonpolymerization.;During the chlorination of alkyl chlorides with molecular chlorine, the involvement of a bridged intermediate led to the formation of vicinal chlorides as the major products. The yields of geminal chlorides increased significantly in the presence of solvents that form complexes with chlorine atoms, but such solvents also decreased the reactivity of the chlorination. Thus the chlorination of poly(vinyl chloride) (PVC) in the presence of complexing solvents was not a useful ...


A Solvent-Free Claisen Condensation Reaction For The Organic Laboratory, John Esteb, Matthew Stockton Dec 2002

A Solvent-Free Claisen Condensation Reaction For The Organic Laboratory, John Esteb, Matthew Stockton

John Esteb

An experiment involving the Claisen condensation reaction for a first-year organic chemistry laboratory is presented. Claisen condensations are routinely covered in organic textbooks but owing to the long reaction times required to reach equilibrium in solution they are seldom explored in the undergraduate teaching laboratory. In this experiment, potassium tert-butoxide and ethyl phenylacetate are heated to 100 °C for 30 minutes under solvent-free conditions to produce 2,4-diphenyl acetoacetate in 80% yield. The solvent-free nature of this procedure greatly reduces the quantity of waste generated by students relative to typical carbonyl condensation experiments.

Note:Link is to the article in ...


A Solvent-Free Oxidation Of Alcohols In An Organic Laboratory, John Esteb, Michael Schelle, Anne Wilson Dec 2002

A Solvent-Free Oxidation Of Alcohols In An Organic Laboratory, John Esteb, Michael Schelle, Anne Wilson

John Esteb

An oxidation experiment for a first-year organic chemistry class is presented. This oxidation utilizes a solid mixture of CuSO4•5H2O and KMnO4 prepared by mortar and pestle. The oxidations take place under solvent-free conditions and near quantitative yields are obtained for the reactions. Thin-layer chromatography is used to monitor the progress of the reaction. This experiment provides for the simple oxidation of a secondary alcohol to a ketone using a relatively nontoxic oxidizing agent under solvent-free conditions.

Note:Link is to the article in a subscription database available to users affiliated with Butler University. Appropriate login information will be required ...