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Medicinal-Pharmaceutical Chemistry Commons

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Arli A Parikesit

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Full-Text Articles in Medicinal-Pharmaceutical Chemistry

The Computation Of Cyclic Peptide With Prolin-Prolin Bond As Fusion Inhibitor Of Denv Envelope Protein Through Molecular Docking And Molecular Dynamics Simulation, Arli A. Parikesit, Hilyatuz Zahroh, Andreas S. Nugroho, Amalia Hapsari, Usman Sumo F. Tambunan Dec 2012

The Computation Of Cyclic Peptide With Prolin-Prolin Bond As Fusion Inhibitor Of Denv Envelope Protein Through Molecular Docking And Molecular Dynamics Simulation, Arli A. Parikesit, Hilyatuz Zahroh, Andreas S. Nugroho, Amalia Hapsari, Usman Sumo F. Tambunan

Arli A Parikesit

A disease that caused by dengue virus (DENV) has become the major health problem of the world. Nowadays, no effective treatment is available to overcome the disease due to the level of dengue virus pathogeneses. A novel treatment method such as antiviral drug is highly necessary for coping with the dengue disease. Envelope protein is one of the non-structural proteins of DENV, which engaged in the viral fusion process. It penetrates into the host cell to transfer its genetic material into the targeted cell followed by replication and establishment of new virus. Thus, the envelope protein can be utilized as ...