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Royal College of Surgeons in Ireland

Chemistry Articles

Aza Compounds

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Bf2-Azadipyrromethene Nir-Emissive Fluorophores With Research And Clinical Potential., Harrison C. Daly, Gonzalo Sampedro, Corentin Bon, Dan Wu, Ghazi Ismail, Ronan A. Cahill, Donal F. O'Shea Jul 2017

Bf2-Azadipyrromethene Nir-Emissive Fluorophores With Research And Clinical Potential., Harrison C. Daly, Gonzalo Sampedro, Corentin Bon, Dan Wu, Ghazi Ismail, Ronan A. Cahill, Donal F. O'Shea

Chemistry Articles

The use of near-infrared fluorescence for in vivo research and intraoperative clinical imaging is rapidly expanding, with new applications being proposed and developed. While imaging hardware and software have significantly progressed in recent times, the molecular fluorescent agents remain a limiting factor. In this report, the design, synthesis, photophysical characterization and bio-medical imaging assessment of two new NIR-fluorophores based on the BF