Open Access. Powered by Scholars. Published by Universities.®

Medicinal-Pharmaceutical Chemistry Commons

Open Access. Powered by Scholars. Published by Universities.®

Royal College of Surgeons in Ireland

Other Chemicals and Drugs

Articles 1 - 1 of 1

Full-Text Articles in Medicinal-Pharmaceutical Chemistry

Discovery Of Small Molecule Fcγriia Antagonists, Michael Thai Trung King Nov 2015

Discovery Of Small Molecule Fcγriia Antagonists, Michael Thai Trung King

PhD theses

Antibodies are Y-shaped proteins that are secreted by B-cells that makes up part of the defence mechanism in the adaptive immune system. Upon infection via invading bacteria and viruses, specific antibodies are produced to target the pathogens. An antibody pathogen complex is formed and this complex interacts with its antibody receptor to be phagocytised or opsonized and is then removed from the body. IgG is one of five classes of antibodies and is the most abundant antibody found in circulation that represents over 75% of serum antibodies in the body. The IgG antibody complex can interact with cells expressing its ...