Open Access. Powered by Scholars. Published by Universities.®

Cell Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

Chromatin

Animal Sciences

Articles 1 - 1 of 1

Full-Text Articles in Cell Biology

Premature Chromosome Condensation Of Synchronized Chinese Hamster Lung Cells, Steven Michael Tucci Jun 1977

Premature Chromosome Condensation Of Synchronized Chinese Hamster Lung Cells, Steven Michael Tucci

Biology Master’s Theses

The orderly, nonrandom pattern of nuclear chromatin is observable when it is condensed as visually distinct and structurally reproducible metaphase chromosomes. Interphase nuclei are susceptible to being induced to condense prematurely when by somatic cell fusion they become exposed to the influence of mitotic nuclei. The mitotic inducer has a differential effect on G1, S, and G­2 chromatin and produces varied premature condensation products. In the following experiments metaphase-G1 fusions yielded single, elongated chromatids. The metaphase-S fusions resulted in pulverized condensation products. Metaphase-G2 fusions produced sister, elongated chromatids.

Sendai virus was used as the fusing agent ...