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Cell Biology Commons

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2014

Undergraduate Honors Theses

Other Cell and Developmental Biology

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Modeling Drosophila Stem Cell Development Through Ex Vivo Live-Cell Imaging Studies, Mohima Sanyal Apr 2014

Modeling Drosophila Stem Cell Development Through Ex Vivo Live-Cell Imaging Studies, Mohima Sanyal

Undergraduate Honors Theses

Stem cell specification, maintenance, and differentiation are imperative to proper organogenesis and tissue maintenance. Understanding the mechanisms and steps of these developmental processes is invaluable to advancing tissue grafting, cancer treatment, and other organ therapies. The Drosophila melanogaster testis is one of the best-characterized systems for studying these processes. Currently, studies in the Drosophila testis have thoroughly characterized when stem cells develop and what the resulting adult testis morphology will be. A major question that remains to be answered is how stem cells develop – what controls what cells become functional stem cells and how stem cell fates are dictated. To ...