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Cell Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

2006

Linfield College

Articles 1 - 1 of 1

Full-Text Articles in Cell Biology

Dynamin As A Mover And Pincher During Cell Migration And Invasion, Anne E. Kruchten, Mark A. Mcniven Jan 2006

Dynamin As A Mover And Pincher During Cell Migration And Invasion, Anne E. Kruchten, Mark A. Mcniven

Faculty Publications

The large GTPase dynamin, long known for its role in endocytosis, has most recently been implicated as a facilitator of cell migration and invasion. Recent observations link dynamin to the cycle of membrane expansion and retraction essential for cell motility. Its role in actin polymerization, membrane deformation and vesiculation, and focal adhesion dynamics are all important for this process, and the new findings provide exciting directions for studies of this ubiquitous and diverse protein family.