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Cell Biology Commons

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University of Massachusetts Medical School Faculty Publications

Animals; Drosophila; Humans; Neural Stem Cells; Neurogenesis; Neuroglia; Neurons; Synapses

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Full-Text Articles in Cell Biology

Cell Biology In Neuroscience: Architects In Neural Circuit Design: Glia Control Neuron Numbers And Connectivity, Megan M. Corty, Marc R. Freeman Nov 2013

Cell Biology In Neuroscience: Architects In Neural Circuit Design: Glia Control Neuron Numbers And Connectivity, Megan M. Corty, Marc R. Freeman

University of Massachusetts Medical School Faculty Publications

Glia serve many important functions in the mature nervous system. In addition, these diverse cells have emerged as essential participants in nearly all aspects of neural development. Improved techniques to study neurons in the absence of glia, and to visualize and manipulate glia in vivo, have greatly expanded our knowledge of glial biology and neuron-glia interactions during development. Exciting studies in the last decade have begun to identify the cellular and molecular mechanisms by which glia exert control over neuronal circuit formation. Recent findings illustrate the importance of glial cells in shaping the nervous system by controlling the number and ...