Open Access. Powered by Scholars. Published by Universities.®

Cell Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

PDF

Conference

Chemorepellent

Articles 1 - 1 of 1

Full-Text Articles in Cell Biology

Netrin-3 Peptide (C-19) Is A Chemorepellent And A Growth Inhibitor In Tetrahymena Thermophila, Jennifer N. Felzien, Brandon R. Kalb, Bethany C. Khol, Katelyn R. Malik, Matthew S. Merical, Lois Parks, David Paulding, Shannon Rappaport, Kenneth W. Ward, Heather G. Kuruvilla Apr 2017

Netrin-3 Peptide (C-19) Is A Chemorepellent And A Growth Inhibitor In Tetrahymena Thermophila, Jennifer N. Felzien, Brandon R. Kalb, Bethany C. Khol, Katelyn R. Malik, Matthew S. Merical, Lois Parks, David Paulding, Shannon Rappaport, Kenneth W. Ward, Heather G. Kuruvilla

The Research and Scholarship Symposium (2013-2019)

The netrins are a family of signaling proteins expressed throughout the animal kingdom. Netrins play important roles in developmental processes such as axonal guidance and angiogenesis. Netrin-1, for example, can act as either a chemoattractant or a chemorepellent for axonal growth cones depending upon the concentration of the protein as well as the cell type. Netrin-1 acts as a growth factor in some mammalian cell types and is also expressed by some tumor cells. Netrin-3 appears to share some signaling apparatus with netrin-1, but is less widely expressed, and its physiological roles are much less understood. Netrin-3 is also used ...