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Full-Text Articles in Cell Biology

Platiscity Of C. Elegans Germline Stem Cells Under Nutritional And Metabolic Stress, Kenneth Trimmer May 2019

Platiscity Of C. Elegans Germline Stem Cells Under Nutritional And Metabolic Stress, Kenneth Trimmer

UT GSBS Dissertations and Theses (Open Access)

Stem cells are integral for tissue maintenance and fertility. Therefore, understanding how stem cells are regulated under stress is imperative. When confronted with acute starvation, stem cells must conserve energy and metabolites to cope with the lack of an external source. Caenorhabditis elegans germline stem cells (GSCs) are an excellent model for studying stem cell properties and regulation as they can divide throughout the life of the organism. While GSCs are an adult stem cell population, their cell cycle structure more closely mimics mouse and human embryonic stem cells with short G1 and long S phases. In this thesis, I ...


Oral Administration Of Coprostanol Producing Microorganisms To Humans To Decrease Plasma Cholesterol Concentration, Donald C. Beitz, Jerry W. Young, Ling Li, Kimberly K. Buhman Aug 1995

Oral Administration Of Coprostanol Producing Microorganisms To Humans To Decrease Plasma Cholesterol Concentration, Donald C. Beitz, Jerry W. Young, Ling Li, Kimberly K. Buhman

Iowa State University Patents

A method of decreasing plasma cholesterol is disclosed. The method includes oral administration of coprostanol-producing bacteria to humans. These organisms, once in the small intestine, will reduce free cholesterol to coprostanol, which is absorbed poorly. Pharmaceutical compositions for delivery are included as are different methods of delivery such as placing the microorganisms in food.