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Cancer Biology Commons

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Full-Text Articles in Cancer Biology

Fighting Demons, Fighting Cancer, Ethan Helm Mar 2008

Fighting Demons, Fighting Cancer, Ethan Helm

Eukaryon

Demons. I’m surrounded by demons. To my left, soul-draining succubi shoot balls of magic, to the right stand acid-flinging Cerberuses, and straight ahead, gigantic, fire-breathing balrogs lurk ominously. First I charge the succubi, killing them quickly with a barrage of Level 20 fireballs. Next, I take the Cerberuses using the same technique. The balrogs, however, are immune to fire. I push F4 to change my spell to chain lightning and electrocute the spawns of Satan. Now, on to Lazarus, the teleporting super demon. I’ll get him though, for I can teleport too!


Role Of Transient Receptor Potential Canonical-6 (Trpc6) Channel In Metastasis Of Glioblastoma Multiforme, Rajarajeshwari Venkataraman Jan 2008

Role Of Transient Receptor Potential Canonical-6 (Trpc6) Channel In Metastasis Of Glioblastoma Multiforme, Rajarajeshwari Venkataraman

Electronic Theses and Dissertations

Glioblastoma multiforme (GBM) is one of the extremely fatal brain tumors. The main reason that makes it so lethal is its capability to invade and spread to other parts of CNS producing secondary tumors. Among other factors hypoxia, reduced oxygen availability, is linked to higher metastatic potential of cancers. Hypoxia causes numerous changes in genome and proteome of the cell. These changes help a normal cell to adapt to nutritional deficiency, but the same changes can increase the malignancy and metastasis in tumor cells. Extensive research by a number of curious scientists reveal that various pathways involving numerous proteins cross-talk ...


Maldi Mass Spectrometry Imaging For The Discovery Of Prostate Carcinoma Biomarkers, Lisa Harris Cazares Jan 2008

Maldi Mass Spectrometry Imaging For The Discovery Of Prostate Carcinoma Biomarkers, Lisa Harris Cazares

Theses and Dissertations in Biomedical Sciences

The elucidation of new biological markers of prostate cancer (PCa) should aid in the detection, and prognosis of this disease. Diagnostic decision making by pathologists in prostate cancer is highly dependent on tissue morphology. The ability to localize disease-specific molecular changes in tissue would help improve this critical pathology decision making process. Direct profiling of proteins in tissue sections using MALDI imaging mass spectrometry (MALDI-IMS) has the power to link molecular detail to morphological and pathological changes, enhancing the ability to identify candidates for new specific biomarkers. However, critical questions remain regarding the integration of this technique with clinical decision ...