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Cancer Biology Commons

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1984

Life and Environmental Sciences Undergraduate Theses

Articles 1 - 2 of 2

Full-Text Articles in Cancer Biology

The Cytotoxic And Kinetic Effects Of Asynchronous Cells Following The Administration Of Vincristine, Meri Firpo Apr 1984

The Cytotoxic And Kinetic Effects Of Asynchronous Cells Following The Administration Of Vincristine, Meri Firpo

Life and Environmental Sciences Undergraduate Theses

A growth curve was constructed for SCCVII-SF, a mouse squamous cell carcinoma cell line, in a culture of modified q-crle's medium. A toxicity curve was constructed for vincristine ,nd SCCVII-SF cells in the exponential phase of growth. Cells in mid-exponential phase were treated with a subtoxic level of vincristine for four hours. A count of mitotic cells was taken at intervals to determine whether vincristine caused a buildup of cells in mitosis after its removal. Results showed that cells continued to collect in mitosis for four hours after the removal of vincristine.


The Late Effects Of Terminated Protracted Whole-Body 60 Co Gamma Irradiation On Beagle Dogs, Mark Elliott Apr 1984

The Late Effects Of Terminated Protracted Whole-Body 60 Co Gamma Irradiation On Beagle Dogs, Mark Elliott

Life and Environmental Sciences Undergraduate Theses

Beagle dogs exposed to protracted Co gamma irradiation were observed for late effects, particularly life shortening ® and fatal tumor incidence. A total of 86 controls and 136 irradiated beagles entered the study, with 60% of these dead as of October 1, 1983. A nearly equal number of beagles of both sexes began If-ray exposure at 400 days of age. The 6 0 Co ¥-rays were given to predetermined total exposures of 600, 1400, 2000, and 4000 R at rates of 5, 10, 17, and 35 R/ day (22 hours/day, 7 days/week), with a few exceptions. Although 40% of ...