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Cancer Biology Commons

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Articles 1 - 10 of 10

Full-Text Articles in Cancer Biology

Sfrp1 Reduction Results In An Increased Sensitivity To Tgf-Β Signaling, Sallie Smith Schneider, Kelly Gauger, Kerry Chenausky, Molly Murray Feb 2011

Sfrp1 Reduction Results In An Increased Sensitivity To Tgf-Β Signaling, Sallie Smith Schneider, Kelly Gauger, Kerry Chenausky, Molly Murray

Sallie W Smith Schneider

Background Transforming growth factor (TGF)-β plays a dual role during mammary gland development and tumorigenesis and has been shown to stimulate epithelial-mesenchymal transition (EMT) as well as cellular migration. The Wnt/β-catenin pathway is also implicated in EMT and inappropriate activation of the Wnt/β-catenin signaling pathway leads to the development of several human cancers, including breast cancer. Secreted frizzled-related protein 1 (SFRP1) antagonizes this pathway and loss of SFRP1 expression is frequently observed in breast tumors and breast cancer cell lines. We previously showed that when SFRP1 is knocked down in immortalized non-malignant mammary epithelial cells, the cells ...


Gold Nanoparticle-Mediated Transfection Of Mammalian Cells, Sallie Smith Schneider, K.K. Sanhu, J.M. Simard, C.M. Mcintosh, V.M. Rotello Dec 2001

Gold Nanoparticle-Mediated Transfection Of Mammalian Cells, Sallie Smith Schneider, K.K. Sanhu, J.M. Simard, C.M. Mcintosh, V.M. Rotello

Sallie W Smith Schneider

No abstract provided.


Regulation Of The Immediate Early Gene Product C-Fos By Erk And Rsk: A Mechanism For Sensing And Propagating Erk Signal Duration, Sallie Smith Schneider, L.O. Murphy, R.H. Chen, D.C. Fingar, J. Blenis Dec 2001

Regulation Of The Immediate Early Gene Product C-Fos By Erk And Rsk: A Mechanism For Sensing And Propagating Erk Signal Duration, Sallie Smith Schneider, L.O. Murphy, R.H. Chen, D.C. Fingar, J. Blenis

Sallie W Smith Schneider

No abstract provided.


Mitogen Activated Protein Kinase Plays A Significant Role In Metaphase Ii Arrest, Spindle Morphology, And Maintenance Of Maturation Promoting Factor Activity In Bovine Oocytes, Sallie Smith Schneider, C.A. Gordo, C.L. He, R.A. Fissore Dec 2000

Mitogen Activated Protein Kinase Plays A Significant Role In Metaphase Ii Arrest, Spindle Morphology, And Maintenance Of Maturation Promoting Factor Activity In Bovine Oocytes, Sallie Smith Schneider, C.A. Gordo, C.L. He, R.A. Fissore

Sallie W Smith Schneider

No abstract provided.


Characterization Of A Mutant T Cell Hybridoma Line With Defects In Tcr-Mediated Apoptotic Pathway, Sallie Smith Schneider, G. Morgan, S.W. Smith, L. Pak, A. Marshak-Rothstein, R. Fissore, B.A. Osborne Dec 1998

Characterization Of A Mutant T Cell Hybridoma Line With Defects In Tcr-Mediated Apoptotic Pathway, Sallie Smith Schneider, G. Morgan, S.W. Smith, L. Pak, A. Marshak-Rothstein, R. Fissore, B.A. Osborne

Sallie W Smith Schneider

No abstract provided.


Private Pathways To A Common Death, Sallie Smith Schneider, B.A. Osborne Dec 1996

Private Pathways To A Common Death, Sallie Smith Schneider, B.A. Osborne

Sallie W Smith Schneider

No abstract provided.


Molecular Events In Thymocyte Apoptosis, Sallie Smith Schneider, B.A. Osborne Dec 1994

Molecular Events In Thymocyte Apoptosis, Sallie Smith Schneider, B.A. Osborne

Sallie W Smith Schneider

No abstract provided.


Apoptotic Signals Delivered Through The T-Cell Receptor Of A T-Cell Hybrid Require The Immediate-Early Gene Nur77, Sallie Smith Schneider, Z.G. Lui, K.A. Mclaughlin, L.M. Schwartz, B.A. Osborne Dec 1993

Apoptotic Signals Delivered Through The T-Cell Receptor Of A T-Cell Hybrid Require The Immediate-Early Gene Nur77, Sallie Smith Schneider, Z.G. Lui, K.A. Mclaughlin, L.M. Schwartz, B.A. Osborne

Sallie W Smith Schneider

No abstract provided.


Do All Programmed Cell Deaths Occur Via Apoptosis?, Sallie Smith Schneider, L.M. Schwartz, M.E.E Jones, B.A. Osborne Dec 1992

Do All Programmed Cell Deaths Occur Via Apoptosis?, Sallie Smith Schneider, L.M. Schwartz, M.E.E Jones, B.A. Osborne

Sallie W Smith Schneider

No abstract provided.


P53 Is Required For Radiation-Induced Apoptosis In Mouse Thymocytes, Sallie Smith Schneider, S.W. Lowe, E.M. Schmitt, B.A. Osborne Dec 1992

P53 Is Required For Radiation-Induced Apoptosis In Mouse Thymocytes, Sallie Smith Schneider, S.W. Lowe, E.M. Schmitt, B.A. Osborne

Sallie W Smith Schneider

No abstract provided.