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Biochemistry, Biophysics, and Structural Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

1991

Immunology

Articles 1 - 1 of 1

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Molecular Mechanisms Controlling Bovine Lymphocyte Homing , Brad Thomas Bosworth Jan 1991

Molecular Mechanisms Controlling Bovine Lymphocyte Homing , Brad Thomas Bosworth

Retrospective Theses and Dissertations

The cDNA clones encoding for the bovine glycoproteins CD44 and LECAM-1 (lectin cell adhesion molecule-1) were isolated and sequenced. The predicted amino acid sequences of bovine CD44 and LECAM-1 had high identities with those of human and murine CD44 and LECAM-1. The high identities of the predicted amino acid sequences of these glycoproteins in the bovine, human and mouse suggest they may have similar functions in all three species. While the overall amino acid identities were high, bovine CD44 had an area of low identity with human and murine CD44 in the extracellular domain and the cytoplasmic tail of bovine ...