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Articles 1 - 30 of 288

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Tracing Nutrient Sources To Lipid Production In Insects Using Stable Isotope (Δ13c, Δ2h) Tracers: Implications For Nutritional Physiology Of Migratory Species., Libesha Anparasan, Keith A. Hobson Jun 2019

Tracing Nutrient Sources To Lipid Production In Insects Using Stable Isotope (Δ13c, Δ2h) Tracers: Implications For Nutritional Physiology Of Migratory Species., Libesha Anparasan, Keith A. Hobson

Western Research Forum

Using stable isotope measurements of insect tissues to determine origin and migratory patterns is well established. However, isotopically determining nutritional origins of lipids, the primary fuel of migration, has not been as thoroughly researched. We explored isotopic links between diet and stored lipids in laboratory raised True armyworm moths (Mythimna unipuncta) using δ13C and δ2H measurements. Pupae were randomly separated into four groups (n=20) and fed isotopically distinct nectar, each consisting of a combination of high δ13C (C4 sugar), or low δ13C (C3 sugar) carbohydrate, with high δ2H (deuterium ...


Knocking Out A Negative Regulator Of Hedgehog Signaling Blocks Differentiation Of Cells Into Neurons, Danielle Margaret Spice, Gregory M. Kelly Ph.D. Jun 2019

Knocking Out A Negative Regulator Of Hedgehog Signaling Blocks Differentiation Of Cells Into Neurons, Danielle Margaret Spice, Gregory M. Kelly Ph.D.

Western Research Forum

Hedgehog (Hh) signaling, one of many different protein signaling pathways found in mammals, is vital in many stage of neural development. A major negative regulator of Hh signaling is a protein known as Suppressor of Fused (SUFU), which acts to sequester the full length Gli transcription factors, proteins that can turn genes on and off, in the cytoplasm or facilitates its conversion to a repressive form. The P19 embryonal carcinoma cell line is a model of hind-brain neuronal differentiation and the involvement of Hh signaling, in particular the role of SUFU in this process has yet to be explored. We ...


The Wet Bridge Transfer System: An Novel In Vitro Tool For Assessing Exogenous Surfactant As A Pulmonary Drug Delivery Vehicle, Brandon J. Baer Jun 2019

The Wet Bridge Transfer System: An Novel In Vitro Tool For Assessing Exogenous Surfactant As A Pulmonary Drug Delivery Vehicle, Brandon J. Baer

Western Research Forum

Background:

Due to its complex branching structure, direct drug delivery to the remote areas of the lung is a major challenge. Consequently, most therapies, such as those treating pulmonary infection and inflammation, must utilize large systemic dosing, with the potential for adverse side effects. A novel alternative strategy is to use exogenous surfactant, a material capable of distributing throughout the lung, as a pulmonary drug delivery vehicle.

Objective:

Utilize an in vitro transferring system to assess exogenous surfactant (BLES) as a pulmonary delivery vehicle for different therapeutics.

Methods:

An in vitro technique was developed to simultaneously study surfactant delivery and ...


Stochastic Modeling Of Neuronal Transport In Various Cellular Geometries, Abhishek Choudhary Mr., Peter Kramer May 2019

Stochastic Modeling Of Neuronal Transport In Various Cellular Geometries, Abhishek Choudhary Mr., Peter Kramer

Biology and Medicine Through Mathematics Conference

No abstract provided.


Studying The Effects Of Electronic Cigarette Exposure On Dna Mutation And Repair In Tetrahymena Thermophila, Tianna Sell, Katie Huisman, Matt F. Kvech Apr 2019

Studying The Effects Of Electronic Cigarette Exposure On Dna Mutation And Repair In Tetrahymena Thermophila, Tianna Sell, Katie Huisman, Matt F. Kvech

Carroll College Student Undergraduate Research Festival

The purpose of our experiment was to answer the question: Does exposure to aerosols expelled from an electronic cigarette affect the APN2 gene expression in Tetrahymena thermophila? It was hypothesized that the expression of APN2 would increase in Tetrahymena that were exposed to aerosol from a vape and that their growth rate would decrease. The mechanism and function of the APN2 gene is known as base excision repair. To test the hypothesis, Tetrahymena were randomly assigned to either a control group or a test group. A contraption was created to extract 12mL of aerosol from a Smok Baby Beast vape ...


Effect Of Lead On Vma1 Atpase Gene Expression And Feeding Behavior In Tetrahymena Thermophila, Sarah Butler, Jazmine E. Townsend Apr 2019

Effect Of Lead On Vma1 Atpase Gene Expression And Feeding Behavior In Tetrahymena Thermophila, Sarah Butler, Jazmine E. Townsend

Carroll College Student Undergraduate Research Festival

Lead is an environmental toxin that has been sown to have deleterious effects on human health, including neurological defects, developmental delays, and bodily pain. The purpose of this experiment was to test whether prolonged exposure to lead altered expression of the VMA1 gene and feeding behavior in the model organism, Tetrahymena thermophila. The VMA1 gene encodes the protein VMA1 (Vacuolar Membrane ATPase) which assists in regulating active transport systems on the vacuolar membrane. We hypothesized that exposure of T. thermophila to lead would result in altered expression of the VMA1 gene and in the feeding behavior of these organisms. For ...


Investigating The Effect Of Phytosterol Concentration On The Des7 Gene And Feeding Behavior In Tetrahymena Thermophila, Nate Burman, Dylan Jones Apr 2019

Investigating The Effect Of Phytosterol Concentration On The Des7 Gene And Feeding Behavior In Tetrahymena Thermophila, Nate Burman, Dylan Jones

Carroll College Student Undergraduate Research Festival

This study examined the impact of phytosterols on DES7 gene expression and feeding behavior in Tetrahymena thermophila. Tetrahymena thermophila are single-celled protists that are often used as model organisms for studying basic processes of Molecular Biology. One major topic in Molecular Biology that has been extensively studied in Tetrahymena is the concept of gene regulation. Gene regulation helps determine whether a certain protein is produced, and this often depends on both the internal and external conditions of the organism. This project took a closer look at the way Tetrahymena process exogenous cholesterol molecules through the production of the DES7 enzyme ...


Effects Of Ethanol On The Gene Expression Of Uracil Dna N-Glycosylase 1 (Ung1) And Growth Rate In Tetrahymena Thermophila, Samantha Mundel, Seth Berkowitz Apr 2019

Effects Of Ethanol On The Gene Expression Of Uracil Dna N-Glycosylase 1 (Ung1) And Growth Rate In Tetrahymena Thermophila, Samantha Mundel, Seth Berkowitz

Carroll College Student Undergraduate Research Festival

Alcohol (ethanol) interferes with human health in a variety of ways such as heart damage, liver damage, and specifically, DNA damage. The purpose of this experiment is to explore the effects of ethanol on the growth rate and expression of the uracil DNA N-Glycosylase (UNG1 ) gene in Tetrahymena thermophila. It was hypothesized that expression of UNG1, the gene that codes for the enzyme uracil DNA N-Glycosylase, would increase and that growth rate would decrease in Tetrahymena cells exposed to ethanol. Previous studies suggest that UNG1 expression is increased when DNA is damaged. This enzyme is involved in base excision repair ...


Csx3: A Crispr-Related Protein W/Rnase Activity, Nate Burman Apr 2019

Csx3: A Crispr-Related Protein W/Rnase Activity, Nate Burman

Carroll College Student Undergraduate Research Festival

Csx3 is a CRIPSR related RNase of unknown purpse obtained from the Archaeal strain Archaeoglobus fulgidus. However, previous literature demonstrates that this thermostable protein dimer is capable of binding small RNA’s. The Lawrence Lab hypothesizes that this activity is due to the presence of a secondary binding domain. In order to investigate this proposed function, Csx3 has been expressed and purified in preparation for enzyme assays and crystallization that will demonstrate the activation of RNase activity by allosteric binding of a nucleic acid oligomer.

Keywords: CRISPR/Cas, RNAse, Csx3


Effect Of Turmeric On Oxidatively Stressed Tetrahymena Thermophila Cells, Logan Meeks, Luke R. Mcentee Apr 2019

Effect Of Turmeric On Oxidatively Stressed Tetrahymena Thermophila Cells, Logan Meeks, Luke R. Mcentee

Carroll College Student Undergraduate Research Festival

Reactive oxygen species (ROSs) are chemically reactive forms of oxygen that, within a cellular environment, form free radicals that interfere with cellular processes and damage DNA. ROSs are routinely produced during oxidative metabolic processes that occur within the mitochondria and their presence in the cell must be tightly regulated. The OXR1 gene encodes a protein that is essential to the degradation of ROSs primarily in the nucleus and in the mitochondria. In this study, we wanted to determine whether turmeric had a protective effect on ROS-induced oxidative stress through regulation of the OXR1 gene in the model organism Tetrahymena thermophila ...


Effect Of Bis (2-Ethylhexyl) Phthalate On Tetrahymena Thermophila Dcl-1 Gene Expression And Conjugation, Talya Vaira, Peyton Twete Apr 2019

Effect Of Bis (2-Ethylhexyl) Phthalate On Tetrahymena Thermophila Dcl-1 Gene Expression And Conjugation, Talya Vaira, Peyton Twete

Carroll College Student Undergraduate Research Festival

Phthalates, often referred to as plasticizers, are a group of chemicals used in hundreds of products including detergents, food packaging, and nail polish. Bis (2-ethylhexyl) phthalates (DEHP) have recently been shown to disrupt endocrine chemical balances, thereby causing reproductive strain. For this project, we wanted to explore how DEHP influences conjugation in Tetrahymena thermophila and to determine how DEHP exposure affects expression of the DCL-1 gene. The DCL-1 gene encodes the protein DCL-1 which is essential for transmitting genetic information during the process of conjugation in T. thermophila. We hypothesized that DEHP will act as a repressor of conjugation resulting ...


Pesticides And Parkinson's: An Investigation Of The Effect Of Roundup Exposure On Drosophila Melanogaster, Siobhan O'Neill Apr 2019

Pesticides And Parkinson's: An Investigation Of The Effect Of Roundup Exposure On Drosophila Melanogaster, Siobhan O'Neill

Carroll College Student Undergraduate Research Festival

From commercial farms to private households, Roundup is the most commonly used herbicide in the United States. In recent years, exposure to Roundup has been correlated with a variety of health problems including Celiac Disease, birth defects, kidney and liver diseases, Alzheimer's Disease, and Parkinson's Disease. To date, the use of Roundup has been banned or restricted in several foreign countries, including the Netherlands, Portugal, Germany and Italy, because it has been classified as a possible carcinogen by the World Health Organization. The goal of this research was to determine the effects of Roundup exposure on dopaminergic neurons ...


The Effects Of Roundup On Tetrahymena Thermophila Growth And Cytochrome P450 Gene Expression, Ethan Viles, Henry Walker Apr 2019

The Effects Of Roundup On Tetrahymena Thermophila Growth And Cytochrome P450 Gene Expression, Ethan Viles, Henry Walker

Carroll College Student Undergraduate Research Festival

Roundup is a very common herbicide in the United States, but has been linked to many detrimental health effects and was classified as ‘probably carcinogenic’ by the World Health Organization in 1994. Not much research has been done to elucidate the possible effects on non-cancer gene pathways.The goal of this project was to research the influence that exposure to Roundup has on the growth of Tetrahymena thermophila and the expression of the cytochrome p450 gene. It was hypothesized that Roundup exposure would change the expression of cytochrome p450 gene and would decrease the growth rate of Tetrahymena thermophila. Background ...


Cell Separation Delay And Membrane Trafficking Defects In Cdc42 Gap Mutants, Haylee Grace Young Apr 2019

Cell Separation Delay And Membrane Trafficking Defects In Cdc42 Gap Mutants, Haylee Grace Young

EURēCA: Exhibition of Undergraduate Research and Creative Achievement

Cytokinesis is the final step in cell division, where a cell separates into two daughter cells. Cytokinesis involves many steps that must be organized in a spatiotemporal manner. In many eukaryotes, it involves the assembly and constriction of an actomyosin ring. The fission yeast Schizosaccharomyces pombe serves as a good model system to study cytokinesis because they divide via actomyosin-dependent-cytokinesis.

The Rho-family of small GTPases are molecules involved in the regulation of cell growth and division. The GTPase Cdc42 helps promote timely onset of ring constriction and septum formation in fission yeast. Studies with many other organisms show that Cdc42 ...


Longitudinal Study Of Lanana Creek, Bayler Barnes, Jackson T. Ortiz, Trace Washburn Apr 2019

Longitudinal Study Of Lanana Creek, Bayler Barnes, Jackson T. Ortiz, Trace Washburn

Undergraduate Research Conference

A longitudinal study was done to collect data on the various conditions of LananaCreek in Nacogdoches, Texas over a seven week span from September 14 to November 2, 2018. The part of the creek studies is a 3.5 mile stretch from East Austin Street to Hoya Soccer Complex, mostly located on the campus of Stephen F. Austin State University. There were 6 different testing sites selected along this expanse. Collection of samples was performed by the General Chemistry I Honors class as part of the laboratory experience. Once collected, the samples were transported back to the lab for testing ...


Extraction And Quantification Of Hydrolyzable Tannins In Acorns From Different Species Of Oak Trees (Quercus Spp.), Sarah Browning, Marshall E. Woodruff Apr 2019

Extraction And Quantification Of Hydrolyzable Tannins In Acorns From Different Species Of Oak Trees (Quercus Spp.), Sarah Browning, Marshall E. Woodruff

Undergraduate Research Conference

Do white-tailed deer (Odocoileus virginianus) prefer to eat certain types of acorns based on tannin content?

Hydrolyzable tannins consist of gallate groups connected via ester linkages to a carbohydrate (D-glucose)

The Prussian Blue method was used to determine hydrolyzable tannin content


The Transesterification Of Hickory Nuts Into Biodiesel Fuel, Hannah Trauger, Madilynn Dewell, Jahida A. Mendoza Apr 2019

The Transesterification Of Hickory Nuts Into Biodiesel Fuel, Hannah Trauger, Madilynn Dewell, Jahida A. Mendoza

Undergraduate Research Conference

• Biodiesel fuels can be produced from a fat and an alcohol via transesterification

• Hickory nuts have a high fat content (~60 % by weight)

• Can nuts from shagbark hickory (Carya ovata) be used to produce a biodiesel fuel using existing acidcatalyzed transesterification methods?


Circadian Rhythmicity And Neurodevelopment Of Disco And Grim Mutations In Drosophila Melanogaster, John Patrick Story Apr 2019

Circadian Rhythmicity And Neurodevelopment Of Disco And Grim Mutations In Drosophila Melanogaster, John Patrick Story

EURēCA: Exhibition of Undergraduate Research and Creative Achievement

The death gene grim and its pathway for apoptosis has been studied extensively in Drosophila Melanogaster. The effects of grim mutations on circadian neurodevelopment and locomotor assays have yet to be investigated. Mutations in the gene disconnected (disco) has been shown to disrupt the normal development of the circadian circuitry, specifically the small ventro-lateral neurons (s-LNv’s). Which has shown to severely decrease rhythmicity during free-running periods. Alternatively, we have observed an increase in rhythmicity during free-running periods in grim mutations. Our goal is to investigate the neurodevelopment of the circadian circuitry and their associated locomotor activities in these Drosophila ...


Peptide Conjugation Of Branched Amphiphilic Peptide Capsules, Baltazar Claro-Martinez Apr 2019

Peptide Conjugation Of Branched Amphiphilic Peptide Capsules, Baltazar Claro-Martinez

Kansas State University Undergraduate Research Conference

In recent years, nanocarrier cellular therapy has been a rapidly growing area for research in the treatment of malignant and infectious diseases – most notably cancer. Conventional cancer treatment has consisted of highly toxic, highly insoluble, untargeted delivery of drugs that kill both cancerous and healthy cells. Research in the Tomich lab consists of the synthesis of Branched Amphiphilic Peptide Capsules (BAPCs), which are self-assembling peptide nanospheres composed of one or both of these branched peptide sequences: h5 and h9. These peptides possess similar molecular characteristics of phosphoglycerides but are synthesized chemically within the lab. Previous publications by the Tomich group ...


Characterization Of A Membrane-Bound Insect Transferrin, Diana Najera Apr 2019

Characterization Of A Membrane-Bound Insect Transferrin, Diana Najera

Kansas State University Undergraduate Research Conference

Characterization of a Membrane-Bound Insect Transferrin

Diana G. Najera, Michelle E. Coca, Kayla E. Nutsch, and Maureen J. Gorman

Department of Biochemistry and Molecular Biophysics, Kansas State University

Transferrins are extracellular proteins that bind iron. Vertebrate transferrins have well-characterized roles in iron transport and immunity, but the functions of transferrins in most other animals are poorly understood. The goals of this study are to identify the functions of transferrin-3 (Tsf3) from Drosophila melanogaster (fruit fly), and to determine whether Tsf3 is conserved in other species of insects. Our experimental approach has been to predict important features of the protein, analyze ...


Pilot Studies Of Two Possible Iron Uptake Mechanisms In Insect Cells, Michelle Coca Apr 2019

Pilot Studies Of Two Possible Iron Uptake Mechanisms In Insect Cells, Michelle Coca

Kansas State University Undergraduate Research Conference

Pilot Studies of Two Possible Iron Uptake Mechanisms in Insect Cells

Michelle E. Coca, Diana G. Najera, and Dr. Maureen J. Gorman

Department of Biochemistry and Molecular Biophysics

College of Arts and Sciences

Iron plays an important role in energy metabolism and other essential physiological processes; however, because iron can also be toxic, its uptake by cells must be strictly regulated. In humans, there is a well-understood pathway of iron uptake and multiple poorly understood pathways. How iron is transported into insect cells is unknown. The goal of this study was to test two models of iron uptake by cultured ...


Boron Uptake In Salt Cedars Via Aquaporins, Alexcis Barnes Apr 2019

Boron Uptake In Salt Cedars Via Aquaporins, Alexcis Barnes

Kansas State University Undergraduate Research Conference

Salt Cedar (Tamarix) is a dicot plant highly tolerant to the chemical boron. This is interesting because for most plants boron is an essential yet toxic metalloid. Plants have a hard time excluding it. The goal of the project is to identify a potential protein sequence (order of amino acids forming a protein) for an aquaporin that allows the transport of boron, moving through a pore. In addition to selecting the sequences, a 3D model of the protein has been constructed to see how boron is entering the cells through the channels of these proteins. A dynamic model is being ...


Netrin-3 And Netrin-4-Like Proteins Are Secreted From Tetrahymena Thermophila, Leah C. Anderton, Nicholas Bradley, Sorrel Paris, Aaron T. Vangeest, Reese Watkins, Kassie E. Young, Heather G. Kuruvilla Apr 2019

Netrin-3 And Netrin-4-Like Proteins Are Secreted From Tetrahymena Thermophila, Leah C. Anderton, Nicholas Bradley, Sorrel Paris, Aaron T. Vangeest, Reese Watkins, Kassie E. Young, Heather G. Kuruvilla

The Research and Scholarship Symposium

Netrins are signaling proteins, acting as chemorepellants or chemoattractants, and their role is especially important in early growth in organisms. In studies involving Tetrahymena thermophila, netrin proteins often act as chemorepellants, so research centered around verifying if this was also true for Netrin-4 protein. Since Netrin-1 and Netrin-3 have been shown to influence neurological and developmental growth in organisms, the implications for discovering the cellular effects of Netrin-4 are significant for human health and research. Through behavioral assays, we were able to confirm that Netrin4 does act as a chemorepellant. In addition, our ELISA and Western blots also helped substantiate ...


Characterization Of A Netrin-4 Like Protein In Tetrahymena Thermophila, Leah Anderton, Nicholas Bradley, Bryce Childers, Levi Fox, Kirstyn Kelley, Lauren Lightbody, Allison Mcclean, Estelle Viaud-Murat, Lydia Watson, Heather G. Kuruvilla Apr 2019

Characterization Of A Netrin-4 Like Protein In Tetrahymena Thermophila, Leah Anderton, Nicholas Bradley, Bryce Childers, Levi Fox, Kirstyn Kelley, Lauren Lightbody, Allison Mcclean, Estelle Viaud-Murat, Lydia Watson, Heather G. Kuruvilla

The Research and Scholarship Symposium

The netrin family of proteins has homeostatic roles in vertebrate development and angiogenesis, and pathophysiological roles in the progression and metastasis of cancer. We have previously characterized a netrin-1-like protein in Tetrahymena thermophila, and have shown that vertebrate netrin-1, netrin-3, and netrin-4 all serve as chemorepellents in this organism. We are currently using Western blotting and immunofluorescence to further characterize the netrin-like proteins in Tetrahymena. Western blotting with our anti-netrin-4 antibody shows a band that is clearly visible in whole cell extract, but shows little reactivity with secreted protein, indicating that most of our netrin-4-like protein remains within the cell ...


Ultrafine Carbon Nanoparticles Activate Inflammasome Signaling And Cell Death In Murine Macrophages, Alexander Soloniuk, Hadley Lamascus, Jay Brewster, John Mann Mar 2019

Ultrafine Carbon Nanoparticles Activate Inflammasome Signaling And Cell Death In Murine Macrophages, Alexander Soloniuk, Hadley Lamascus, Jay Brewster, John Mann

Seaver College Research And Scholarly Achievement Symposium

Carbon black (CB) is the primary nanoparticulate component of air pollution from fossil fuel combustion. This work examines the cellular impact of ultrafine carbon (carbon black, CB) nanoparticles, that range in size down to 30 nm, upon murine macrophages. The size analysis of the carbon black nanoparticles was performed using atomic force microscopy (AFM) and transmission electron microscopy (TEM) techniques. RAW246.7 macrophage cells were exposed to CB doses ranging from 50 – 200 ug/ml in complete media. Analysis of cell survival over time revealed elevated rates of significant nuclear degradation and cell lifting after 48 hours of exposure, and ...


Targeted Therapy For The Future: The Use Of Novel Antimicrobial Peptides Against P. Aeurginosa, Matthew Froid Mar 2019

Targeted Therapy For The Future: The Use Of Novel Antimicrobial Peptides Against P. Aeurginosa, Matthew Froid

Student Research and Creative Activity Fair

Pathogenic bacteria, such as the gram-negative bacterium Pseudomonas aeruginosa, are becoming resistant to our current arsenal of antibiotics at an alarming rate. P. aeruginosa is a leading cause of nosocomial acquired infections and is a primary co-morbidity in patients with compromised immune systems. One potential source of new antibiotic agents is antimicrobial peptides. Antimicrobial peptides (AMPs) are small proteins, and some have shown a high degree of efficacy and broad-spectrum activity against both Gram-positive and Gram-negative bacteria. An experimental AMP that has been developed by Dr. Wang at UNMC, DASamp2, has shown to be effective against virulent bacteria, including P ...


Data Analytics Pipeline For Rna Structure Analysis Via Shape, Quinn Nelson Mar 2019

Data Analytics Pipeline For Rna Structure Analysis Via Shape, Quinn Nelson

Student Research and Creative Activity Fair

Coxsackievirus B3 (CVB3) is a cardiovirulent enterovirus from the family Picornaviridae. The RNA genome houses an internal ribosome entry site (IRES) in the 5’ untranslated region (5’UTR) that enables cap-independent translation. Ample evidence suggests that the structure of the 5’UTR is a critical element for virulence. We probe RNA structure in solution using base-specific modifying agents such as dimethyl sulfate as well as backbone targeting agents such as N-methylisatoic anhydride used in Selective 2’-Hydroxyl Acylation Analyzed by Primer Extension (SHAPE). We have developed a pipeline that merges and evaluates base-specific and SHAPE data together with statistical analyses ...


Large Scale Dynamical Model Of Macrophage/Hiv Interactions, Matthew M. Froid Mar 2019

Large Scale Dynamical Model Of Macrophage/Hiv Interactions, Matthew M. Froid

Student Research and Creative Activity Fair

Properties emerge from the dynamics of large-scale molecular networks that are not discernible at the individual gene or protein level. Mathematical models - such as probabilistic Boolean networks - of molecular systems offer a deeper insight into how these emergent properties arise. Here, we introduce a non-linear, deterministic Boolean model of protein, gene, and chemical interactions in human macrophage cells during HIV infection. Our model is composed of 713 nodes with 1583 interactions between nodes and is responsive to 38 different inputs including signaling molecules, bacteria, viruses, and HIV viral particles. Additionally, the model accurately simulates the dynamics of over 50 different ...


Analyzing Neuronal Dendritic Trees With Convolutional Neural Networks, Olivier Trottier, Jonathon Howard Jan 2019

Analyzing Neuronal Dendritic Trees With Convolutional Neural Networks, Olivier Trottier, Jonathon Howard

Yale Day of Data

In the biological sciences, image analysis software are used to detect, segment or classify a variety of features encountered in living matter. However, the algorithms that accomplish these tasks are often designed for a specific dataset, making them hardly portable to accomplish the same tasks on images of different biological structures. Recently, convolutional neural networks have been used to perform complex image analysis on a multitude of datasets. While applications of these networks abound in the technology industry and computer science, use cases are not as common in the academic sciences. Motivated by the generalizability of neural networks, we aim ...


A Three State Model Can Explain The Dynamics Of Class Iv Drosophila Dendritic Tips, Sabyasachi Sutradhar Jan 2019

A Three State Model Can Explain The Dynamics Of Class Iv Drosophila Dendritic Tips, Sabyasachi Sutradhar

Yale Day of Data

No abstract provided.