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Biochemistry, Biophysics, and Structural Biology Commons

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Chemistry Faculty Publications

1963

Articles 1 - 2 of 2

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Carbon Dioxide Fixation In The Brain / Soll Berl, Genkichiro Takagaki, Donald D Clarke, And Heinrich Waelsch From The New York Psychiatric Institute And The Colleg Eof Physicians And Surgeons, Columbia University, New York, New York, Soll Berl, Genkichiro Takagaki, Donald Dudley Clarke Phd, Heinrich Waelsch Jan 1963

Carbon Dioxide Fixation In The Brain / Soll Berl, Genkichiro Takagaki, Donald D Clarke, And Heinrich Waelsch From The New York Psychiatric Institute And The Colleg Eof Physicians And Surgeons, Columbia University, New York, New York, Soll Berl, Genkichiro Takagaki, Donald Dudley Clarke Phd, Heinrich Waelsch

Chemistry Faculty Publications

Carbon dioxide fixation in brain was studied in cats to which NaHC14O3, with and without ammonia, was administered by intracarotid infusion. Glutamic and aspartic acids, glutamine, glutathione, and γ-aminobutyric acid were isolated from blood, brain, and liver, and their specific activities were determined. The data indicate a significant incorporation of CO2 into the amino acids of the cerebral cortex, presumably by way of the citric acid cycle. Without simultaneous ammonia infusion, the specific activity of aspartic acid is 3 times that of glutamine, whereas in the presence of ammonia the ratios of specific activity of both compounds are closer to ...


Radicinin: Revision Of Its Structure Obtained From Nmr Measurements / D. D. Clarke F. F. Nord N. S. Bhacca Laboratory Of Organic Chemistry And Enzymology Fordham University Bronx 58, New York Spectroscopy Applications Laboratory Varian Associates Palo Alto, California, Donald Dudley Clarke Phd, Friedrich F. Nord, N. S. Bhacca Jan 1963

Radicinin: Revision Of Its Structure Obtained From Nmr Measurements / D. D. Clarke F. F. Nord N. S. Bhacca Laboratory Of Organic Chemistry And Enzymology Fordham University Bronx 58, New York Spectroscopy Applications Laboratory Varian Associates Palo Alto, California, Donald Dudley Clarke Phd, Friedrich F. Nord, N. S. Bhacca

Chemistry Faculty Publications

Radicinin, a metabolite of the formula C12H1205 was isolated from the carrot plant pathogen Stemphylium Tadicinum and described in earlier communications. Hansen isolated a metabolite from S. radicinum that inhibited the growth of Lepidium sativum and named it stemphylone. From the physical and chemical properties described for stemphylone it would appear to be identical with radicinin