Open Access. Powered by Scholars. Published by Universities.®

Biochemistry, Biophysics, and Structural Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 3 of 3

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Acute And Chronic Cadmium Exposure Promotes E-Cadherin Degradation In Mcf7 Breast Cancer Cells, Esmeralda Ponce, Maggie Louie, Mary B. Sevigny Sep 2015

Acute And Chronic Cadmium Exposure Promotes E-Cadherin Degradation In Mcf7 Breast Cancer Cells, Esmeralda Ponce, Maggie Louie, Mary B. Sevigny

Maggie Louie

Cadmium is an environmental carcinogen that usually enters the body at minute concentrations through diet or cigarette smoke and bioaccumulates in soft tissues. In past studies, cadmium has been shown to contribute to the development of more aggressive cancer phenotypes including increased cell migration and invasion. This study aims to determine if cadmium exposure-both acute and chronic-contributes to breast cancer progression by interfering with the normal functional relationship between E-cadherin and β-catenin. An MCF7 breast cancer cell line (MCF7-Cd) chronically exposed to 10(-7)  M CdCl2 was previously developed and used as a model system to study chronic exposures, whereas ...


Cadmium As An Estrogen Receptor Modulator, Maggie Louie May 2011

Cadmium As An Estrogen Receptor Modulator, Maggie Louie

Maggie Louie

No abstract available


The Effects Of Cadmium On Breast Cancer Progression, Maggie Louie Oct 2010

The Effects Of Cadmium On Breast Cancer Progression, Maggie Louie

Maggie Louie

No abstract available