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Biochemistry, Biophysics, and Structural Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

Physiology

2015

Chemistry & Biochemistry Graduate Theses & Dissertations (1986-2018)

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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Improved Methods For Understanding The Gut Microbiome, Justine Woodhouse Debelius Jan 2015

Improved Methods For Understanding The Gut Microbiome, Justine Woodhouse Debelius

Chemistry & Biochemistry Graduate Theses & Dissertations (1986-2018)

The gut microbiome plays a profound role in human health. Over the last decade, much work has been done to define differences between microbial communities in healthy and diseased individuals. Studies of healthy individual have been small, and failed to address the multifactorial influences on the microbiome. However, little effort has focused on comparisons between the effects, in part due to the multivariate and complex nature of the data, which does not fit into the traditional paradigm for effect size calculations. This leaves questions about the relative impact of common practices on the microbiome, in comparison to the impact of ...