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Biochemistry, Biophysics, and Structural Biology Commons

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Articles 1 - 8 of 8

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Circadian Clock-Controlled Genes Isolated From Neurospora Crassa Are Late Night- To Early Morning-Specific, Deborah Bell-Pedersen, Mari L. Shinohara, Jennifer J. Loros, Jay C. Dunlap Nov 1996

Circadian Clock-Controlled Genes Isolated From Neurospora Crassa Are Late Night- To Early Morning-Specific, Deborah Bell-Pedersen, Mari L. Shinohara, Jennifer J. Loros, Jay C. Dunlap

Open Dartmouth: Faculty Open Access Scholarship

An endogenous circadian biological clock controls the temporal aspects of life in most organisms, including rhythmic control of genes involved in clock output pathways. In the fungus Neurospora crassa, one pathway known to be under control of the clock is asexual spore (conidia) development. To understand more fully the processes that are regulated by the N. crassa circadian clock, systematic screens were carried out for genes that oscillate at the transcriptional level. Time-of-day-specific cDNA libraries were generated and used in differential screens to identify six new clock-controlled genes (ccgs). Transcripts specific for each of the ccgs preferentially accumulate ...


Distribution Of Poly(Adp-Ribose) Glycohydrolase In Different Functional Domains Of The Cell Nucleus, Gustavo Pacheco-Rodriguez B.S., M.S. Aug 1996

Distribution Of Poly(Adp-Ribose) Glycohydrolase In Different Functional Domains Of The Cell Nucleus, Gustavo Pacheco-Rodriguez B.S., M.S.

Theses and Dissertations

Pacheco-Rodriguez, Gustavo, Distribution of Poly(ADP-ribose) Glycohydrolase in Different Functional Domains of the Cell Nucleus. Doctor of Philosophy (Biomedical Sciences), August, 1996, 147 pp, 3 tables, 44 illustrations, bibliography, 138 titles. In this study, the distributor poly(ADP-ribose) glycohydrolase (PARG) in different subdomains of the cell nucleus and the role of non-covalent interactions of poly(ADP-ribose) with nuclear proteins have been characterized. An assay that allows the simultaneous determination of specific non-covalent interactions of poly (ADP-ribose) with nuclear proteins as well as PARG activity by high resolution polyacrylamide gel electrophoresis was developed. This method was made possible by the enzymatic ...


Ultrasound Three- Dimensional Velocity Measurements By Feature Tracking, Gregory R. Bashford, Olaf T. Von Ramm May 1996

Ultrasound Three- Dimensional Velocity Measurements By Feature Tracking, Gregory R. Bashford, Olaf T. Von Ramm

Biomedical Imaging and Biosignal Analysis Laboratory

This article describes a new angle-independent method suitable for three-dimensional (3-D) blood flow velocity measurement that tracks features of the ultrasonic speckle produced by a pulse echo system. In this method, a feature is identified and followed over time to detect motion. Other blood flow velocity measurement methods typically estimate velocity using one- (1-D) or two-dimensional (2-D) spatial and time information. Speckle decorrelation due to motion in the elevation dimension may hinder this estimate of the true 3-D blood flow velocity vector. Feature tracking is a 3-D method with the ability to measure the true blood velocity vector rather than ...


The Assessment Of Osteoinductivity Of Human Allograft Demineralized Bone Matrix By In Vivo And In Vitro Assay Models, Min Zhang Apr 1996

The Assessment Of Osteoinductivity Of Human Allograft Demineralized Bone Matrix By In Vivo And In Vitro Assay Models, Min Zhang

Theses and Dissertations in Biomedical Sciences

The osteoinductive potential (osteoinductivity) is a very important aspect of demineralized bone matrix (DBM) as a biomaterial. This study is directed at establishing qualitative and quantitative assays of the osteoinductivity of human DBM. Further aspects of this study include an assessment of the effects of the production process, matrix characterization, and donor related factors on osteoinductivity of the DBM.

Athymic mice were chosen as the animal model for use in the in vivo bioassay. Implantation of DBM in muscle pouches provided for much higher osteoinductivity (remineralization to 10% calcium) than subcutaneous site implantation (remineralization to 1.6% calcium). Histological observations ...


Natural History Note: Elaphe Obsoleta Obsoleta (Black Rat Snake) - Foraging, James Withgott, Charles Amlaner Dec 1995

Natural History Note: Elaphe Obsoleta Obsoleta (Black Rat Snake) - Foraging, James Withgott, Charles Amlaner

Charles J. Amlaner

No abstract provided.


Monitoring Body Temperature And Nocturnal Activity Of Snakes With Implanted Transmitters, James Withgott, Charles Amlaner Dec 1995

Monitoring Body Temperature And Nocturnal Activity Of Snakes With Implanted Transmitters, James Withgott, Charles Amlaner

Charles J. Amlaner

No abstract provided.


Natural History Note: Elaphe Obsoleta Obsoleta (Black Rat Snake) - Response To Fire, James Withgott, Charles Amlaner Dec 1995

Natural History Note: Elaphe Obsoleta Obsoleta (Black Rat Snake) - Response To Fire, James Withgott, Charles Amlaner

Charles J. Amlaner

No abstract provided.


Transmitter Implantation Techniques In Black Rat Snakes, Charles Amlaner, James Withgott Dec 1995

Transmitter Implantation Techniques In Black Rat Snakes, Charles Amlaner, James Withgott

Charles J. Amlaner

No abstract provided.