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Biochemistry, Biophysics, and Structural Biology Commons

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Articles 1 - 4 of 4

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Laminin Potentiates Differentiation Of Pcc4uva Embryonal Carcinoma Into Neurons, T. M. Sweeney, Roy C. Ogle, C. D. Little Sep 1990

Laminin Potentiates Differentiation Of Pcc4uva Embryonal Carcinoma Into Neurons, T. M. Sweeney, Roy C. Ogle, C. D. Little

Medical Diagnostics & Translational Sciences Faculty Publications

The embryonal carcinoma PCC4uva differentiates into neurons in response to treatment with retinoic acid and dbcAMP. We used this in vitro model system to study the effects of laminin on early neural differentiation. Laminin substrata markedly potentiate neural differentiation of retinoic acid and dbcAMP-treated cultures. Only laminin induced more rapid neural cell body clustering, neurite growth and neurite fasciculation as compared to type IV collagen, type I collagen, and fibronectin substrata. Exogenous laminin substrata promoted greater cell attachment, cellular spreading and growth to confluence than type IV collagen, type I collagen, fibronectin and glass substrata. Laminin-induced effects were inhibited by ...


Deercare: A Deer Population And Hunting Simulation Model, Claude Barnett, David Stewart, Charles Amlaner Apr 1990

Deercare: A Deer Population And Hunting Simulation Model, Claude Barnett, David Stewart, Charles Amlaner

Charles J. Amlaner

No abstract provided.


The Introduction Of Simulation Modeling To Wildlife Management In Arkansas, Charles Amlaner, Claude Barnett, David Stewart Apr 1990

The Introduction Of Simulation Modeling To Wildlife Management In Arkansas, Charles Amlaner, Claude Barnett, David Stewart

Charles J. Amlaner

No abstract provided.


The 5Å Resolution Crystal Structure Of Adenylosuccinate Synthetase From Escherichia Coli , Michael Alan Serra Jan 1990

The 5Å Resolution Crystal Structure Of Adenylosuccinate Synthetase From Escherichia Coli , Michael Alan Serra

Retrospective Theses and Dissertations

The technique of X-ray crystallography has been employed to determine the structure of adenylosuccinate synthetase from Escherichia coli to a resolution of 5A. Three crystalline forms of the enzyme have been obtained. The structure determination of the P21 crystal form was pursued due to its excellent diffraction properties and its rapid and reproducible growth. The P21 form crystallizes as a dimer. Unit cell parameters are as follows: a = 73.31(9)A, b = 72.23(7)A, c = 82.87(9)A, [beta] = 108.59°(6). The unit cell volume is 416,700(1,200)A[superscript]3.;A suitable ...