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Biochemistry, Biophysics, and Structural Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

Molecular Biology

2009

Series

Alkylamides

Articles 1 - 1 of 1

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Metabolic Profiling Of Echinacea Genotypes And A Test Of Alternative Taxonomic Treatments, Lankun Wu, Philip M. Dixon, Basil J. Nikolau, George A. Kraus, Mark P. Widrlechner, Eve S. Wurtele Jan 2009

Metabolic Profiling Of Echinacea Genotypes And A Test Of Alternative Taxonomic Treatments, Lankun Wu, Philip M. Dixon, Basil J. Nikolau, George A. Kraus, Mark P. Widrlechner, Eve S. Wurtele

NCRPIS Publications and Papers

The genus Echinacea is used as an herbal medicine to treat a variety of ailments. To better understand its potential chemical variation, 40 Echinacea accessions encompassing broad geographical and morphological diversity were evaluated under controlled conditions. Metabolites of roots from these accessions were analyzed by HPLC-photo diode array (HPLC-PDA), GC-MS, and multivariate statistical methods. In total, 43 lipophilic metabolites, including 24 unknown compounds, were detected. Weighted principal component analysis (WPCA) and clustering analysis of the levels of these metabolites across Echinacea accessions, based on Canberra distances, allowed us to test two alternative taxonomic treatments of the genus, with the further ...