Open Access. Powered by Scholars. Published by Universities.®

Biochemistry, Biophysics, and Structural Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 10 of 10

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Materials And Methods For The Alteration Of Enzyme And Acetyl Coa Levels In Plants, Basil J. Nikolau, Eve S. Wurtele, David J. Oliver, Patrick S. Schnable, Tsui-Jung Wen Apr 2009

Materials And Methods For The Alteration Of Enzyme And Acetyl Coa Levels In Plants, Basil J. Nikolau, Eve S. Wurtele, David J. Oliver, Patrick S. Schnable, Tsui-Jung Wen

Iowa State University Patents

The present invention provides nucleic acid and amino acid sequences of acetyl CoA synthetase (ACS), plastidic pyruvate dehydrogenase (pPDH), ATP citrate lyase (ACL),Arabidopsis pyruvate decarboxylase (PDC), and Arabidopsis aldehyde dehydrogenase (ALDH), specifically ALDH-2 and ALDH-4. The present invention also provides a recombinant vector comprising a nucleic acid sequence encoding one of the aforementioned enzymes, an antisense sequence thereto or a ribozyme therefor, a cell transformed with such a vector, antibodies to the enzymes, a plant cell, a plant tissue, a plant organ or a plant in which the level of an enzyme has been altered, and a method of ...


Functional Nucleic Acid Probes And Uses Thereof, Marit Nilsen-Hamilton Oct 2006

Functional Nucleic Acid Probes And Uses Thereof, Marit Nilsen-Hamilton

Iowa State University Patents

The present invention provides functional nucleic acid probes, and methods of using functional nucleic acid probes, for binding a target to carry out a desired function. The probes have at least one functional nucleic acid, at least one regulating nucleic acid, and at least one attenuator. The functional nucleic acid is maintained in an inactive state by the attenuator and activated by the regulating nucleic acid only in the presence of a regulating nucleic acid target. In its activated state the functional nucleic acid can bind to its target to carry out a desired function, such as generating a signal ...


Height Referencing Biochemical Cassette, Marc D. Porter, Vivian W. Jones, Curtis L. Mosher, Eric Henderson Nov 2000

Height Referencing Biochemical Cassette, Marc D. Porter, Vivian W. Jones, Curtis L. Mosher, Eric Henderson

Iowa State University Patents

A height referencing biochemical cassette comprising of a surface suitable to act as a coupling agent, a height referencing indicator, and molecules bonded to the surface. This cassette is a capable of use to test for bonding to these molecules through measuring the height difference between the indicator and the surface. This invention provides an efficient means to quickly and easily test for bonding of molecules to other molecules.


Activated Mono-, Di-, And Polysaccharides Reaction Products Thereof, Their Preparation And Uses, John F. Robyt, Rupendra Mukerjea May 1999

Activated Mono-, Di-, And Polysaccharides Reaction Products Thereof, Their Preparation And Uses, John F. Robyt, Rupendra Mukerjea

Iowa State University Patents

Reaction at the interface of an organic solution containing an acidic reactant and an aqueous alkaline solution containing nonreducing carbohydrates such as sucrose, sugar alcohols, cyclodextrins, and polysaccharides imparts a specificity to the reaction for one or more of the primary alcohol groups of the carbohydrate reactant. The resulting activated, nonreducing carbohydrate intermediate can then be converted to a series of substantially pure, low molecular weight reaction products, including a sucrose trimer and dianhydrosucrose, and to a series of substantially pure, higher molecular weight reaction products, including 6-O-sucro cyclodextrins and poly-6-O-sucro amylose.


Linear And Cyclic Sucrose Reaction Products, Their Preparation And Their Use, John F. Robyt, Rupendra Makerjea Mar 1999

Linear And Cyclic Sucrose Reaction Products, Their Preparation And Their Use, John F. Robyt, Rupendra Makerjea

Iowa State University Patents

Sucrose ester and ether products, useful as food or beverage bulking agents, reduced calorie sweeteners, fat replacement agents, stabilizing agents, thickening agents and emulsifying agents; adhesives; biodegradable plastics and films; sizing agents for paper and textiles; ethical pharmaceuticals and new fibers are prepared by using a two-phase reaction system in which sucrose is dissolved in an alkaline, aqueous solution and an acidic reagent such as a bifunctional acid dichloride or epoxide is added to the sucrose in a water-immiscible organic solvent. Several types of products are produced: water-insoluble sucrose ester (ether) copolymers; water-soluble sucrose ester (ether) copolymers; sucrose ester (ether ...


Apparatus And Method For Transient Thermal Infrared Spectrometry Of Flowable Enclosed Materials, John F. Mcclelland, Roger W. Jones Mar 1993

Apparatus And Method For Transient Thermal Infrared Spectrometry Of Flowable Enclosed Materials, John F. Mcclelland, Roger W. Jones

Iowa State University Patents

A method and apparatus for enabling analysis of a flowable material enclosed in a transport system having an infrared transparent wall portion. A temperature differential is transiently generated between a thin surface layer portion of the material and a lower or deeper portion of the material sufficient to alter the thermal infrared emission spectrum of the material from the black-body thermal infrared emission spectrum of the material, and the altered thermal infrared emission spectrum is detected through the infrared transparent portion of the transport system while the altered thermal infrared emission spectrum is sufficiently free of self-absorption by the material ...


Retinoic Acid Glucuronide Preparations For Application To The Skin, Arun B. Barua, Desiree Gunning, James A. Olson Dec 1991

Retinoic Acid Glucuronide Preparations For Application To The Skin, Arun B. Barua, Desiree Gunning, James A. Olson

Iowa State University Patents

A method and preparation are described for treating human skin with retinoic acid glucuronide (RAG) in a topical carrier. For treatment of acne or wrinkled skin, RAG can be applied in an effective amount which is nonirritating to the skin. Retinoid dermatitis, an objectionable side effect of topical application of retinoid compounds, can thereby be avoided.


Apparatus And Method For Transient Thermal Infrared Emission Spectrometry, John F. Mcclelland, Roger W. Jones Dec 1991

Apparatus And Method For Transient Thermal Infrared Emission Spectrometry, John F. Mcclelland, Roger W. Jones

Iowa State University Patents

A method and apparatus for enabling analysis of a solid material (16, 42) by applying energy from an energy source (20, 70) top a surface region of the solid material sufficient to cause transient heating in a thin surface layer portion of the solid material (16, 42) so as to enable transient thermal emission of infrared radiation from the thin surface layer portion, and by detecting with a spectrometer/detector (28, 58) substantially only the transient thermal emission of infrared radiation from the thin surface layer portion of the solid material. The detected transient thermal emission of infrared radiation is ...


Apparatus And Method For Transient Thermal Infrared Spectrometry, John F. Mcclelland, Roger W. Jones Dec 1991

Apparatus And Method For Transient Thermal Infrared Spectrometry, John F. Mcclelland, Roger W. Jones

Iowa State University Patents

A method and apparatus for enabling analysis of a material (16, 42) by applying a cooling medium (20, 54) to cool a thin surface layer portion of the material and to transiently generate a temperature differential between the thin surface layer portion and the lower portion of the material sufficient to alter the thermal infrared emission spectrum of the material from the black-body thermal infrared emission spectrum of the material. The altered thermal infrared emission spectrum of the material is detected by a spectrometer/detector (28, 50) while the altered thermal infrared emission spectrum is sufficiently free of self-absorption by ...


Non-Teratogenic Vitamin A Preparation For Women Of Child-Bearing Age, Arun B. Barua, Desiree Gunning, James A. Olson Oct 1991

Non-Teratogenic Vitamin A Preparation For Women Of Child-Bearing Age, Arun B. Barua, Desiree Gunning, James A. Olson

Iowa State University Patents

For treatment of acne the glucuronide of retinoic acid (retinoyl β-glucuronide) is orally administered to women of child-bearing age who are capable of conception. This therapy is safer than the oral administration of retinoic acid because retinoic acid glucuronide is essentially non-teratogenic at dose levels effective for the acne treatment. The retinoic acid glucuronide can be in all-trans or 13-cis form.