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Biochemistry, Biophysics, and Structural Biology Commons

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Molecular Biology

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University of Connecticut

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> Bioinformatics

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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Quorum Sensing In Archaea, Charles Mackin May 2011

Quorum Sensing In Archaea, Charles Mackin

Honors Scholar Theses

Bacteria coordinate cell density dependent behaviors by communicating through chemical intermediaries in a process called quorum sensing. In a bacterial culture, individual cells will constitutively produce signal molecules, termed autoinducers, and export them into the environment. When the concentration of autoinducers reaches a threshold, the cells sense that they are in a specific situation, which requires the upregulation of certain genes. This upregulation causes the bacteria to produce proteins that allow them to take part in a coordinated population-wide behavior.

In bacteria that are naturally competent, or capable of importing DNA from the environment, the expression of competence genes is ...