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Biochemistry, Biophysics, and Structural Biology Commons

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Molecular Biology

Dissertations

2007

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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Characterization Of Molecular Events Following Heavy Metal Cadmium Exposure: A Cellular Regulatory Symphony In Response To Early Cadmium Insult, Chin-Ju Jean Hsiao Jun 2007

Characterization Of Molecular Events Following Heavy Metal Cadmium Exposure: A Cellular Regulatory Symphony In Response To Early Cadmium Insult, Chin-Ju Jean Hsiao

Dissertations

Cadmium, a non-essential toxic heavy metal, has been classified as a human carcinogen and one of the most hazardous substances in our environment. Since it can circulate within the food chain, has a long biological half-life and can bio-accumulate, it has the potential to induce detrimental health effects linked to toxicity, cancer and chronic diseases.

In recent years progress has been made to dissect and understand the molecular mechanisms underlying the effects of cadmium exposure. However, few studies have focused on investigating potential protective and/or defense mechanisms naturally applied by cells upon initial exposure, prior to any damage or ...