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Biochemistry, Biophysics, and Structural Biology Commons

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Cancer Biology

1980

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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Immunological And Immunohistochemical Methods Used To Study Chromatin Neoantigens Of Novikoff Hepatoma, Steven Binette, Timothy O'Connor Apr 1980

Immunological And Immunohistochemical Methods Used To Study Chromatin Neoantigens Of Novikoff Hepatoma, Steven Binette, Timothy O'Connor

Life and Environmental Sciences Undergraduate Theses

The micro-complement fixation test was used to assay the potency and specificity of rabbit antisera to chromosomal antigens from Novikoff hepatoma and normal rat liver. The complement fixation titration patterns suggest the presence of only a few species of molecules bearing neochromatin antigens. A immunofluorescent technique was adapted to Novikoff hepatoma cells and resulted in the positive staining of Novikoff chromatin and negligible staining in normal rat liver cells.