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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Calcium-Stimulated Regulatory Volume Decrease In Salmo Salar And Alligator Mississipiensis Erythrocytes, Chloe Wormser
The mechanisms by which cells compensate for volume fluctuations are not clearly understood and vary among species. Research efforts in our lab have focused on elucidating the pathways involved in regulatory volume decrease (RVD), the process activated in response to cell swelling that allows for volume recovery. Previously, fluorescence microscopy studies performed by Light et al. (2005) revealed that in salmon red blood cells, cell swelling elicits a rise in intracellular Ca2+ concentration (visualized using fluorescence microscopy and the Ca2+ indicator fluo-4-AM). This was most likely due Ca2+ influx from the extracellular environment, because it was not observed in cells ...