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2019

Faculty Publications

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Full-Text Articles in Life Sciences

Subsurface Mimo: A Beamforming Design In Internet Of Underground Things For Digital Agriculture Applications, Abdul Salam Aug 2019

Subsurface Mimo: A Beamforming Design In Internet Of Underground Things For Digital Agriculture Applications, Abdul Salam

Faculty Publications

In underground (UG) multiple-input and multiple-output (MIMO), the transmit beamforming is used to focus energy in the desired direction. There are three different paths in the underground soil medium through which the waves propagates to reach at the receiver. When the UG receiver receives a desired data stream only from the desired path, then the UG MIMO channel becomes three path (lateral, direct, and reflected) interference channel. Accordingly, the capacity region of the UG MIMO three path interference channel and degrees of freedom (multiplexing gain of this MIMO channel requires careful modeling). Therefore, expressions are required for the degree of ...


Lignin Biopolymers In The Age Of Controlled Polymerization, Mitra S. Ganewatta, Hasala N. Lokupitiya, Chuanbing Tang Jul 2019

Lignin Biopolymers In The Age Of Controlled Polymerization, Mitra S. Ganewatta, Hasala N. Lokupitiya, Chuanbing Tang

Faculty Publications

Polymers made from natural biomass are gaining interest due to the rising environmental concerns and depletion of petrochemical resources. Lignin isolated from lignocellulosic biomass is the second most abundant natural polymer next to cellulose. The paper pulp process produces industrial lignin as a byproduct that is mostly used for energy and has less significant utility in materials applications. High abundance, rich chemical functionalities, CO2 neutrality, reinforcing properties, antioxidant and UV blocking abilities, as well as environmental friendliness, make lignin an interesting substrate for materials and chemical development. However, poor processability, low reactivity, and intrinsic structural heterogeneity limit lignins′ polymeric applications ...


Identification And Characterization Of Preferred Dna-Binding Sites For The Thermus Thermophilus Hb8 Transcriptional Regulator Ttha0973, James Shell Cox, Kristi Moncja, Mykala Mckinnes, Michael W. Van Dyke Jul 2019

Identification And Characterization Of Preferred Dna-Binding Sites For The Thermus Thermophilus Hb8 Transcriptional Regulator Ttha0973, James Shell Cox, Kristi Moncja, Mykala Mckinnes, Michael W. Van Dyke

Faculty Publications

Advances in genomic sequencing have allowed the identification of a multitude of genes encoding putative transcriptional regulatory proteins. Lacking, often, is a fuller understanding of the biological roles played by these proteins, the genes they regulate or regulon. Conventionally this is achieved through a genetic approach involving putative transcription factor gene manipulation and observations of changes in an organism’s transcriptome. However, such an approach is not always feasible or can yield misleading findings. Here, we describe a biochemistry-centric approach, involving identification of preferred DNA-binding sequences for the Thermus thermophilus HB8 transcriptional repressor TTHA0973 using the selection method Restriction Endonuclease ...


Time-Restricted Feeding Plus Resistance Training In Active Females: A Randomized Trial, Grant M. Tinsley, M. Lane Moore, Austin J. Graybeal, Trisha A. Vandusseldorp Jul 2019

Time-Restricted Feeding Plus Resistance Training In Active Females: A Randomized Trial, Grant M. Tinsley, M. Lane Moore, Austin J. Graybeal, Trisha A. Vandusseldorp

Faculty Publications

Background A very limited amount of research has examined intermittent fasting (IF) programs, such as time-restricted feeding (TRF), in active populations. Objective Our objective was to examine the effects of TRF, with or without β-hydroxy β-methylbutyrate (HMB) supplementation, during resistance training (RT). Methods This study employed a randomized, placebo-controlled, reduced factorial design and was double-blind with respect to supplementation in TRF groups. Resistance-trained females were randomly assigned to a control diet (CD), TRF, or TRF plus 3 g/d HMB (TRFHMB). TRF groups consumed all calories between 1200 h and 2000 h, whereas the CD group ate regularly from breakfast ...


Student-Athlete Compensation: An Alternative Compensation Model For All Athletes Competing In Ncaa Athletics, Mike Stocz, Nicholas Schlereth, Dax Crum, Alonzo Maestas, John Barnes Jul 2019

Student-Athlete Compensation: An Alternative Compensation Model For All Athletes Competing In Ncaa Athletics, Mike Stocz, Nicholas Schlereth, Dax Crum, Alonzo Maestas, John Barnes

Faculty Publications

The Ed O’Bannon case (O’Bannon v. National Collegiate Athletic Association, 2015) has brought student-athlete compensation to the national spotlight. While the NCAA continues to defend its policy of amateurism, the time for college athlete compensation may soon become a reality (NCAA Division I Manual, 2019). Recent college athlete compensation models have explored revenue sharing models similar to that of professional sports leagues, although previous research failed to develop a compensation model for athletes in sports beyond basketball and football (Huma & Staurowsky, 2013). The current research argues for a more applied, market economy compensation model to offer fair compensation ...


Comparison Of Age And Growth Parameters Of Invasive Red Lionfish (Pterois Volitans) Across The Northern Gulf Of Mexico, Alexander Q. Fogg, Joseph T. Evans, Mark S. Peterson, Nancy Brown-Peterson, Eric R. Hoffmayer, G. Walter Ingram Jr. Jul 2019

Comparison Of Age And Growth Parameters Of Invasive Red Lionfish (Pterois Volitans) Across The Northern Gulf Of Mexico, Alexander Q. Fogg, Joseph T. Evans, Mark S. Peterson, Nancy Brown-Peterson, Eric R. Hoffmayer, G. Walter Ingram Jr.

Faculty Publications

Invasive red lionfish (Pterois volitans) have spread rapidly throughout the northern Gulf of Mexico (GOM) partly because of their high growth rate. Red lionfish were collected from the northern GOM across 3 ecological regions from 2012 through 2015. For male and female red lionfish, relationships between weight and total length (TL) were differnt by ecological region. Males acheives a greater mean weight adjusted for TL (333.6 g [standar errer (SE) 3.6]) than females (195.1 g [SE 3.7]). A subsample of 1607 pairs of sagittal otoliths (from 744 males, 716 females, and 147 fish of unknown or ...


Temporal And Spatial Dynamics Of Competitive Parapatry In Chewing Lice, David J. Hafner, Mark S. Hafner, Theresa A. Spradling, Jessica E. Light, James W. Demastes Jul 2019

Temporal And Spatial Dynamics Of Competitive Parapatry In Chewing Lice, David J. Hafner, Mark S. Hafner, Theresa A. Spradling, Jessica E. Light, James W. Demastes

Faculty Publications

We synthesize observations from 1979 to 2016 of a contact zone involving two subspecies of pocket gophers (Thomomys bottae connectens and T. b. opulentus) and their respective chewing lice (Geomydoecus aurei and G. centralis) along the Rio Grande Valley in New Mexico, U.S.A., to test predictions about the dynamics of the zone. Historically, the natural flood cycle of the Rio Grande prevented contact between the two subspecies of pocket gophers. Flood control measures completed in the 1930s permitted contact, thus establishing the hybrid zone between the pocket gophers and the contact zone between their lice (without hybridization). Since ...


Species Composition Influences Soil Nutrient Depletion And Plantphysiology In Prairie Agroenergy Feedstocks, Mark E. Sherrard, Kenneth Elgersma, Jordan M.A. Koos, Catherine M. Kokemuller, Hannah E. Dietz, Alec J. Glidden, Christina M. Carr, Cynthia A. Cambardella Jul 2019

Species Composition Influences Soil Nutrient Depletion And Plantphysiology In Prairie Agroenergy Feedstocks, Mark E. Sherrard, Kenneth Elgersma, Jordan M.A. Koos, Catherine M. Kokemuller, Hannah E. Dietz, Alec J. Glidden, Christina M. Carr, Cynthia A. Cambardella

Faculty Publications

High-diversity mixtures of perennial tallgrass prairie vegetation could be useful biomass feed-stocks for marginal farmland in the Midwestern United States. These agroenergy crops can help meet cel-lulosic agrofuel targets while also enhancing other ecosystem services on the landscape. One proposedadvantage of high-diversity prairie biomass feedstocks is that they should become nutrient limited at aslower rate than monoculture feedstocks. In this study, we examine rates of soil nutrient depletion and thephysiology and performance of a focal species (switchgrass,Panicum virgatumL.) in four prairie agroen-ergy feedstocks with different species composition and diversity. The feedstocks in this study were a1-species switchgrass monoculture, a ...


Linking Nutrient Stoichiometry To Zika Virus Transmission In A Mosquito, Andrew S. Paige, Shawna K. Bellamy, Barry W. Alto, Catherine L. Dean, Donald A. Yee Jun 2019

Linking Nutrient Stoichiometry To Zika Virus Transmission In A Mosquito, Andrew S. Paige, Shawna K. Bellamy, Barry W. Alto, Catherine L. Dean, Donald A. Yee

Faculty Publications

Food quality and quantity serve as the basis for cycling of key chemical elements in trophic interactions; yet the role of nutrient stoichiometry in shaping host–pathogen interactions is under appreciated. Most of the emergent mosquito-borne viruses affecting human health are transmitted by mosquitoes that inhabit container systems during their immature stages, where allochthonous input of detritus serves as the basal nutrients. Quantity and type of detritus (animal and plant) were manipulated in microcosms containing newly hatched Aedes aegypti mosquito larvae. Adult mosquitoes derived from these microcosms were allowed to ingest Zika virus-infected blood and then tested for disseminated infection ...


Discovery And Characterization Of Bacteriophage Luckybarnes, Savannah L. Underwood, Amanda Foto, Amanda F. Ray, Alexander E. Nelms, Keyshawn L. Kennedy, Shelby G. Hartley, Logan M. Ryals, Chandan Gurung, William A. D'Angelo, Welkin H. Pope, Dmitri V. Mavrodi Jun 2019

Discovery And Characterization Of Bacteriophage Luckybarnes, Savannah L. Underwood, Amanda Foto, Amanda F. Ray, Alexander E. Nelms, Keyshawn L. Kennedy, Shelby G. Hartley, Logan M. Ryals, Chandan Gurung, William A. D'Angelo, Welkin H. Pope, Dmitri V. Mavrodi

Faculty Publications

Here, we report the genome sequence of LuckyBarnes, a newly isolated singleton siphovirus that infects Brevibacterium iodinum ATCC 15728 and has a 50,774-bp genome with 67 predicted genes.


Repurposing Of Glycine-Rich Proteins In Abiotic And Biotic Stresses In The Lone-Star Tick (Amblyomma Americanum), Rebekah Bullard, Surendra Raj Sharma, Pradipta Kumar Das, Sarah E. Morgan, Shahid Karim Jun 2019

Repurposing Of Glycine-Rich Proteins In Abiotic And Biotic Stresses In The Lone-Star Tick (Amblyomma Americanum), Rebekah Bullard, Surendra Raj Sharma, Pradipta Kumar Das, Sarah E. Morgan, Shahid Karim

Faculty Publications

Tick feeding requires the secretion of a huge number of pharmacologically dynamic proteins and other molecules which are vital for the formation of the cement cone, the establishment of the blood pool and to counter against the host immune response. Glycine-rich proteins (GRP) are found in many organisms and can function in a variety of cellular processes and structures. The functional characterization of the GRPs in the tick salivary glands has not been elucidated. GRPs have been found to play a role in the formation of the cement cone; however, new evidence suggests repurposing of GRPs in the tick physiology ...


Is Selenoprotein K Required For Borrelia Burgdorferi Infection Within The Tick Vector Ixodes Scapularis?, Deepak Kumar, Monica Embers, Thomas N. Mather, Shahid Karim Jun 2019

Is Selenoprotein K Required For Borrelia Burgdorferi Infection Within The Tick Vector Ixodes Scapularis?, Deepak Kumar, Monica Embers, Thomas N. Mather, Shahid Karim

Faculty Publications

Background: Tick selenoproteins are involved in regulating oxidative and endoplasmic reticulum stress during prolonged tick feeding on mammalian hosts. How selenoproteins are activated upon tick-borne pathogen infection is yet to be defined.

Methods: To examine the functional role of selenoprotein K in Borrelia burgdorferi infection within the tick host Ixodes scapularis, RNA interference (RNAi)-based gene silencing was performed.

Results: Selenoprotein K is an endoplasmic reticulum (ER)-resident protein and a component of the ERAD complex involved in ER homeostasis. A qRT-PCR assay revealed the significant upregulation of selenogene K (selenoK) expression in B. burgdorferi-infected tick tissues. Silencing of ...


Expenditure, Coping, And Academic Behaviors Among Food-Insecure College Students At 10 Higher Education Institutes In The Appalachian And Southeastern Regions, Rebecca L. Hagedorn, Laura H. Mcarthur, Lanae B. Hood, Maureen Berner, Elizabeth T. Anderson Steeves, Carol L. Connell, Elizabeth Wall-Bassett, Marsha Spence, Oyinlola Toyin Babatunde, E. Brooke Kelly, Julia F. Waity, J. Porter Lillis, Melissa D. Olfert Jun 2019

Expenditure, Coping, And Academic Behaviors Among Food-Insecure College Students At 10 Higher Education Institutes In The Appalachian And Southeastern Regions, Rebecca L. Hagedorn, Laura H. Mcarthur, Lanae B. Hood, Maureen Berner, Elizabeth T. Anderson Steeves, Carol L. Connell, Elizabeth Wall-Bassett, Marsha Spence, Oyinlola Toyin Babatunde, E. Brooke Kelly, Julia F. Waity, J. Porter Lillis, Melissa D. Olfert

Faculty Publications

Background

A number of studies have measured college student food insecurity prevalence higher than the national average; however, no multicampus regional study among students at 4-y institutions has been undertaken in the Appalachian and Southeast regions of the United States. Objectives

The aims of this study were to determine the prevalence of food insecurity among college students in the Appalachian and Southeastern regions of the United States, and to determine the association between food-insecurity status and money expenditures, coping strategies, and academic performance among a regional sample of college students. Methods

This regional, cross-sectional, online survey study included 13,642 ...


Genistein Has Antiviral Activity Against Herpes B Virus And Acts Synergistically With Antiviral Treatments To Reduce Effective Dose, Julia C. Lecher, Nga Diep, Peter W. Krug, Julia K. Hilliard May 2019

Genistein Has Antiviral Activity Against Herpes B Virus And Acts Synergistically With Antiviral Treatments To Reduce Effective Dose, Julia C. Lecher, Nga Diep, Peter W. Krug, Julia K. Hilliard

Faculty Publications

Herpes B virus is a deadly zoonotic agent that can be transmitted to humans from the macaque monkey, an animal widely used in biomedical research. Currently, there is no cure for human B virus infection and treatments require a life-long daily regimen of antivirals, namely acyclovir and ganciclovir. Long-term antiviral treatments have been associated with significant debilitating side effects, thus, there is an ongoing search for alternative efficacious antiviral treatment. In this study, the antiviral activity of genistein was quantified against B virus in a primary cell culture model system. Genistein prevented plaque formation of B virus and reduced virus ...


The Kinesin‐3 Motor, Klp‐4, Mediates Axonal Organization And Cholinergic Signaling In Caenorhabditis Elegans, Margaret E. Magaletta, Kendall J. Perkins, Catherine P. Deuchler, Jay N. Pieczynski May 2019

The Kinesin‐3 Motor, Klp‐4, Mediates Axonal Organization And Cholinergic Signaling In Caenorhabditis Elegans, Margaret E. Magaletta, Kendall J. Perkins, Catherine P. Deuchler, Jay N. Pieczynski

Faculty Publications

Microtubule plus‐end directed trafficking is dominated by kinesin motors, yet kinesins differ in terms of cargo identity, movement rate, and distance travelled. Functional diversity of kinesins is especially apparent in polarized neurons, where long distance trafficking is required for efficient signal transduction‐behavioral response paradigms. The Kinesin‐3 superfamily are expressed in neurons and are hypothesized to have significant roles in neuronal signal transduction due to their high processivity. Although much is known about Kinesin‐3 motors mechanistically in vitro, there is little known about their mechanisms in vivo. Here, we analyzed KLP‐4, the Caenorhabditis elegans homologue of ...


Agreement Between The Open Barbell And Tendo Linear Position Transducers For Monitoring Barbell Velocity During Resistance Exercise, Adam M. Gonzalez, Gerald T. Mangine, Robert W. Spitz, Jamie J. Ghigiarelli May 2019

Agreement Between The Open Barbell And Tendo Linear Position Transducers For Monitoring Barbell Velocity During Resistance Exercise, Adam M. Gonzalez, Gerald T. Mangine, Robert W. Spitz, Jamie J. Ghigiarelli

Faculty Publications

To determine the agreement between the Open Barbell (OB) and Tendo weightlifting analyzer (TWA) for measuring barbell velocity, eleven men (19.4 ± 1.0 y) performed one set of 2–3 repetitions at four sub-maximal percentage loads, [i.e., 30, 50, 70, and 90% one-repetition maximum (1RM)] in the back (BS) and front squat (FS) exercises. During each repetition, peak and mean barbell velocity were recorded by OB and TWA devices, and the average of the 2–3 repetitions was used for analyses. Although the repeated measures analysis of variance revealed significantly (p ≤ 0.005) greater peak and mean velocity ...


In Silico Identification Of Genetic Mutations Conferring Resistance To Acetohydroxyacid Synthase Inhibitors: A Case Study Of Kochia Scoparia, Yan Li, Michael D. Netherland, Chaoyang Zhang, Huixiao Hong, Ping Gong May 2019

In Silico Identification Of Genetic Mutations Conferring Resistance To Acetohydroxyacid Synthase Inhibitors: A Case Study Of Kochia Scoparia, Yan Li, Michael D. Netherland, Chaoyang Zhang, Huixiao Hong, Ping Gong

Faculty Publications

Mutations that confer herbicide resistance are a primary concern for herbicide-based chemical control of invasive plants and are often under-characterized structurally and functionally. As the outcome of selection pressure, resistance mutations usually result from repeated long-term applications of herbicides with the same mode of action and are discovered through extensive field trials. Here we used acetohydroxyacid synthase (AHAS) of Kochia scoparia (KsAHAS) as an example to demonstrate that, given the sequence of a target protein, the impact of genetic mutations on ligand binding could be evaluated and resistance mutations could be identified using a biophysics-based computational approach. Briefly, the ...


Experimental Evidence Supportive Of The Quantum Dna Model, F. Matthew Mihelic May 2019

Experimental Evidence Supportive Of The Quantum Dna Model, F. Matthew Mihelic

Faculty Publications

The DNA molecule can be modeled as a quantum logic processor in which electron spin qubits are held coherently in each nucleotide in a logically and thermodynamically reversible enantiomeric symmetry, and can be coherently conducted along the pi-stacking interactions of aromatic nucleotide bases, while simultaneously being spin-filtered via the helicity of the DNA molecule. Entangled electron pairs can be separated by that spin-filtering, held coherently at biological temperatures in the topologically insulated nucleotide quantum gates, and incorporated into separate DNA strands during DNA replication. Two separate DNA strands that share quantum entangled electrons can be mitotically divided into individual cells ...


The Effects Of Ambient Temperature And Lighting Intensity On Wheel-Running Behavior In A Diurnal Rodent, The Nile Grass Rat (Arvicanthis Niloticus), Garrett M. Fogo, Alyssa M. Goodwin, Ohanes S. Khacherian, Brandi J. Ledbetter, Andrew J. Gall May 2019

The Effects Of Ambient Temperature And Lighting Intensity On Wheel-Running Behavior In A Diurnal Rodent, The Nile Grass Rat (Arvicanthis Niloticus), Garrett M. Fogo, Alyssa M. Goodwin, Ohanes S. Khacherian, Brandi J. Ledbetter, Andrew J. Gall

Faculty Publications

Environmental conditions, such as the light-dark cycle and temperature, affect the display of circadian rhythmicity and locomotor activity patterns in mammals. Here, we tested the hypothesis that manipulating these environmental conditions would affect wheel-running activity patterns in a diurnal rodent, the Nile grass rat (Arvicanthis niloticus). Grass rats are diurnal in the field, however, a subset switch from a day-active pattern to a night-active pattern of activity after the introduction of a running wheel. The mechanism of this chronotype switch remains largely unknown. In the present study, grass rats were presented with running wheels in 12:12 light-dark conditions. First ...


Algal-Mediated Priming Effects On The Ecological Stoichiometry Of Leaf Litter Decomposition: A Meta-Analysis, Halvor M. Halvorson, Steven N. Francoeur, Robert H. Findlay, Kevin A. Kuehn Apr 2019

Algal-Mediated Priming Effects On The Ecological Stoichiometry Of Leaf Litter Decomposition: A Meta-Analysis, Halvor M. Halvorson, Steven N. Francoeur, Robert H. Findlay, Kevin A. Kuehn

Faculty Publications

In aquatic settings, periphytic algae exude labile carbon (C) that can significantly suppress or stimulate heterotrophic decomposition of recalcitrant C via priming effects. The magnitude and direction of priming effects may depend on the availability and stoichiometry of nutrients like nitrogen (N) and phosphorus (P), which can constrain algal and heterotrophic activity; in turn, priming may affect heterotrophic acquisition not only of recalcitrant C, but also N and P. In this study, we conducted a meta-analysis of algal-mediated priming across leaf litter decomposition experiments to investigate (1) bottom-up controls on priming intensity by dissolved N and P concentrations, and (2 ...


Mycoprotein: The Future Of Nutritious Nonmeat Protein, A Symposium Review, Tim Finnigan, Benjamin Wall, Peter Wilde, Francis Stephens, Steve Taylor, Marjorie Freedman Apr 2019

Mycoprotein: The Future Of Nutritious Nonmeat Protein, A Symposium Review, Tim Finnigan, Benjamin Wall, Peter Wilde, Francis Stephens, Steve Taylor, Marjorie Freedman

Faculty Publications

Mycoprotein is an alternative, nutritious protein source with a meat-like texture made from Fusarium venenatum, a naturally occurring fungus. Its unique method of production yields a significantly reduced carbon and water footprint relative to beef and chicken. Mycoprotein, sold as Quorn, is consumed in 17 countries, including the United States. In line with current dietary guidelines, mycoprotein is high in protein and fiber, and low in fat, cholesterol, sodium, and sugar. Mycoprotein may help maintain healthy blood cholesterol levels, promote muscle synthesis, control glucose and insulin levels, and increase satiety. It is possible that some susceptible consumers will become sensitized ...


Individual Differences Influence Exercise Behavior: How Personality, Motivation, And Behavioral Regulation Vary Among Exercise Mode Preferences, Allyson G. Box, Yuri Feito, Chris Brown, Steven J. Petruzzello Apr 2019

Individual Differences Influence Exercise Behavior: How Personality, Motivation, And Behavioral Regulation Vary Among Exercise Mode Preferences, Allyson G. Box, Yuri Feito, Chris Brown, Steven J. Petruzzello

Faculty Publications

Personality traits, participatory motives, and behavior regulation have been linked to physical activity engagement. It is possible that these dimensions are associated with the type of physical activity one chooses to engage. Thus, the purpose of this study was to examine individual differences in those participating in various primary modes of physical activity (PMA) and determine which individual differences are predictive of exercise frequency. Methods 403 adults (36.3 ± 11.6 yrs, 35.5% male) completed an online survey. The survey included questions related to their PMA, items for the Big Five Inventory (BFI), Exercise Motivation Inventory (EMI-2), and the ...


An Effective Model For Engaging Faculty And Undergraduate Students In Neuroscience Outreach With Middle Schoolers, Peter J. Vollbrecht, Riley S. Frenette, Andrew J. Gall Apr 2019

An Effective Model For Engaging Faculty And Undergraduate Students In Neuroscience Outreach With Middle Schoolers, Peter J. Vollbrecht, Riley S. Frenette, Andrew J. Gall

Faculty Publications

Engaging undergraduate students in science outreach events is critical for improving future communication between scientists and community members. Outreach events are opportunities for faculty and undergraduates to utilize active learning strategies to engage non-scientists in scientific questions and principles. Through careful design of outreach events, undergraduate students can practice science communication skills while reaching populations of the public that remain underserved and underrepresented in scientific fields. Here we describe a classroom outreach event designed to give a broad overview of the field of neuroscience to middle school students of all backgrounds by delivering the content in school, during school hours ...


Too Much Workplace Sitting: A Brief Historical Perspective, Raymond Jones, Daniel P. Credeur, Stephanie M. Mccoy Apr 2019

Too Much Workplace Sitting: A Brief Historical Perspective, Raymond Jones, Daniel P. Credeur, Stephanie M. Mccoy

Faculty Publications

Sedentary behavior is a risk factor for the development of chronic diseases, especially those of cardiovascular and metabolic origins. Prolonged sitting is one of the most common sedentary behaviors among adults. Individuals sit for hours every day for several reasons, including work and or physical limitations. Historical accounts regarding the negative health effects of prolonged sitting began with early epidemiological studies, which sparked a breakout of research examining this behavior in the workplace setting. Understanding the risks associated with prolonged workplace sitting is important when considering workplace interventions, such as sit-stand workstations. These interventions appear to be beneficial in reducing ...


Sex-Specific Growth And Reproductive Dynamics Of Red Drum In The Northern Gulf Of Mexico, Corbin F. Bennetts, Robert T. Leaf, Nancy J. Brown-Peterson Apr 2019

Sex-Specific Growth And Reproductive Dynamics Of Red Drum In The Northern Gulf Of Mexico, Corbin F. Bennetts, Robert T. Leaf, Nancy J. Brown-Peterson

Faculty Publications

The Red Drum Sciaenops ocellatus stock is heavily targeted in the Gulf of Mexico (GOM) by recreational fishers and supports a small commercial fishery in Mississippi. Despite their popularity, little recent work has been done to describe their life history. In this work, we describe sex‐specific growth and reproductive dynamics of Red Drum collected from the northern GOM from September 2016 through October 2017. We evaluated seven candidate growth models and found that the three‐parameter von Bertalanffy growth function (VBGF) was the best candidate length‐at‐age model. No significant difference in growth between sexes was observed with ...


High Intensity Functional Training (Hift) And Competitions: How Motives Differ By Length Of Participation, Allyson G. Box, Yuri Feito, Chris Brown, Katie M. Heinrich Mar 2019

High Intensity Functional Training (Hift) And Competitions: How Motives Differ By Length Of Participation, Allyson G. Box, Yuri Feito, Chris Brown, Katie M. Heinrich

Faculty Publications

High Intensity Functional Training (HIFT) is a unique fitness method that promotes an active lifestyle and has seen exponential and continual growth over the last two decades. Motivation to exercise is likely to change over time as individuals’ motives to initiate exercise may be different than those which motivate them to maintain an exercise program. The purpose of this study was to examine the motivational factors reported by individuals who actively engage in HIFT with varying length of participation and competition levels. 737 adults (32.4 ± 8.2 years) with more than three-months of HIFT experience completed an online version ...


The Role Of Temperature In Affecting Carry-Over Effects And Larval Competition In The Globally Invasive Mosquito Aedes Albopictus, Nnaemeka F. Ezeakacha, Donald Yee Mar 2019

The Role Of Temperature In Affecting Carry-Over Effects And Larval Competition In The Globally Invasive Mosquito Aedes Albopictus, Nnaemeka F. Ezeakacha, Donald Yee

Faculty Publications

Background

Ectotherms, like mosquitoes, have evolved specific responses to variation in environmental conditions like temperature, and these responses could confer a fitness benefit or cost when carried-over to different life stages. However, effects of temperature on animals with complex life-cycles often only focus on part of their life-cycle, or only consider how single aspects of life-history may carry over to new stages. Herein we investigated how temperature affects intraspecific larval competition and carry-over effects from larval to adult stages in the widespread invasive Asian tiger mosquito Aedes albopictus.

Methods

For larval competition, larvae were reared at three densities (10, 20 ...


Predicting Protein Residue-Residue Contacts Using Random Forests And Deep Networks, Joseph Luttrell Iv, Tong Liu, Chaoyang Zhang, Zheng Wang Mar 2019

Predicting Protein Residue-Residue Contacts Using Random Forests And Deep Networks, Joseph Luttrell Iv, Tong Liu, Chaoyang Zhang, Zheng Wang

Faculty Publications

No abstract provided.


Similarities And Differences Between Variants Called With Human Reference Genome Hg19 Or Hg38, Bohu Pan, Rebecca Kusko, Wenming Xiao, Yuantin Zheng, Zhichao Liu, Chunlin Xiao, Sugunadevi Sakkiah, Wenjing Guo, Ping Gong, Chaoyang Zhang, Weigong Ge, Leming Shi, Weida Tong, Huixiao Hong Mar 2019

Similarities And Differences Between Variants Called With Human Reference Genome Hg19 Or Hg38, Bohu Pan, Rebecca Kusko, Wenming Xiao, Yuantin Zheng, Zhichao Liu, Chunlin Xiao, Sugunadevi Sakkiah, Wenjing Guo, Ping Gong, Chaoyang Zhang, Weigong Ge, Leming Shi, Weida Tong, Huixiao Hong

Faculty Publications

Background

Reference genome selection is a prerequisite for successful analysis of next generation sequencing (NGS) data. Current practice employs one of the two most recent human reference genome versions: HG19 or HG38. To date, the impact of genome version on SNV identification has not been rigorously assessed.

Methods

We conducted analysis comparing the SNVs identified based on HG19 vs HG38, leveraging whole genome sequencing (WGS) data from the genome-in-a-bottle (GIAB) project. First, SNVs were called using 26 different bioinformatics pipelines with either HG19 or HG38. Next, two tools were used to convert the called SNVs between HG19 and HG38. Lastly ...


Tadkb:Family Classification And A Knowledge Base Of Topologically Associating Domains, Tong Liu, Jacob Porter, Chenguang Zhao, Hao Zhu, Nan Wang, Zheng Sun, Yin-Yuan Mo, Zheng Wang Mar 2019

Tadkb:Family Classification And A Knowledge Base Of Topologically Associating Domains, Tong Liu, Jacob Porter, Chenguang Zhao, Hao Zhu, Nan Wang, Zheng Sun, Yin-Yuan Mo, Zheng Wang

Faculty Publications

Background

Topologically associating domains (TADs) are considered the structural and functional units of the genome. However, there is a lack of an integrated resource for TADs in the literature where researchers can obtain family classifications and detailed information about TADs.

Results

We built an online knowledge base TADKB integrating knowledge for TADs in eleven cell types of human and mouse. For each TAD, TADKB provides the predicted three-dimensional (3D) structures of chromosomes and TADs, and detailed annotations about the protein-coding genes and long non-coding RNAs (lncRNAs) existent in each TAD. Besides the 3D chromosomal structures inferred by population Hi-C, the ...