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Identifying Exclusion Genes Of Bacteriophage Hk239, Ali Wright
Honors College Capstone Experience/Thesis Projects
Temperate bacteriophage can adopt either a lytic or a lysogenic lifestyle. In the lytic lifestyle, the bacteriophage infects a cell, uses the host's cellular machinery to replicate, and lyses the cell to release the phage progeny. In the lysogenic lifestyle the bacteriophage genome is integrated into the bacterial genome to generate a prophage. Most of the genes of the prophage are repressed. However, those genes that are expressed have a wide variety of functions including exclusion, the prevention of phage infection. Lysogens of bacteriophage HK239 have the ability to exclude a wide variety of phage, including (lambda), T4rII, Plvir ...