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Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2006

DNA

Western Kentucky University

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Full-Text Articles in Life Sciences

Identifying Exclusion Genes Of Bacteriophage Hk239, Ali Wright Jan 2006

Identifying Exclusion Genes Of Bacteriophage Hk239, Ali Wright

Honors College Capstone Experience/Thesis Projects

Temperate bacteriophage can adopt either a lytic or a lysogenic lifestyle. In the lytic lifestyle, the bacteriophage infects a cell, uses the host's cellular machinery to replicate, and lyses the cell to release the phage progeny. In the lysogenic lifestyle the bacteriophage genome is integrated into the bacterial genome to generate a prophage. Most of the genes of the prophage are repressed. However, those genes that are expressed have a wide variety of functions including exclusion, the prevention of phage infection. Lysogens of bacteriophage HK239 have the ability to exclude a wide variety of phage, including (lambda), T4rII, Plvir ...