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Full-Text Articles in Life Sciences

Cacna1a: The Exciting Headache Gene, Michael White Jan 2006

Cacna1a: The Exciting Headache Gene, Michael White

Eukaryon

Migraine headache is a common, chronic, debilitating pain that affects roughly 6-8% of men and 15-18% of women in the U.S. and Europe (WHO, 2004). In the U.S., the annual cost of migraine treatment ranges from 13-17 billion dollars (Goldberg, 2005; Blumenfeld, 2005). Often it causes deficits in cognition, function, and sleep. Until recently, no research had defined the molecular basis for such a widespread illness. However, a remarkable study conducted by Maagdenberg and colleagues (2004) suggested that mutations in a gene encoding neuronal calcium channels were the molecular basis for migraine.


Molecular Genetics: Discoveries With Your Own Dna, Lokesh Kukreja Jan 2006

Molecular Genetics: Discoveries With Your Own Dna, Lokesh Kukreja

Eukaryon

No abstract provided.


Eating Disorders: Could They Be Autoimmune Diseases?, Melissa Stevenson Jan 2006

Eating Disorders: Could They Be Autoimmune Diseases?, Melissa Stevenson

Eukaryon

Recent research on Anorexia Nervosa (AN) and Bulimia Nervosa (BN) has shown an increasing understanding of the biological and physiological abnormalities that underlie the development of an eating disorder. Cultural pressures, individual and family experiences, along with physiological and genetic systems all appear to contribute to the onset of these disorders. There is significant evidence for genetic factors in the susceptibility of AN/BN, however current research has focused on the possibly of characterizing eating disorders as being an autoimmune disease. Autoantibodies have recently been discovered in patients with eating disorders and could be affecting the biological pathway of many ...