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Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2006

Genetics and Genomics

Biology Master’s Theses

Gene Disruption

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Full-Text Articles in Life Sciences

The Role Of Ilv5p Interacting Factors In Mitochondrial Dna Stability, Anthony J. Mirando Jun 2006

The Role Of Ilv5p Interacting Factors In Mitochondrial Dna Stability, Anthony J. Mirando

Biology Master’s Theses

The ease of manipulating yeast allows for advanced studies on the factors affecting the mitochondrial DNA mutation rates. The control mechanisms of the mitochondrial DNA mutation rate has been determined to involve the dual function protein, Ilv5p. The Ilv5p plays an integral role in the proper segregation of newly replicated mitochondrial DNA into daughter cells during cell division. The focus of this study is to find unknown factors involved in mitochondrial DNA stability. This study uses the Ilv5p to pull unknown factors out of the many genes that comprise the yeast genome. The identification of interacting factors of the Ilv5p ...