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Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2006

Genetics and Genomics

Biology Master’s Theses

Biology THESIS 1616

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Full-Text Articles in Life Sciences

Characterization Of Fmp35: A Novel Gene And Its Role In Mitochondrial Dna Stability, Chad A. Cornelius Jan 2006

Characterization Of Fmp35: A Novel Gene And Its Role In Mitochondrial Dna Stability, Chad A. Cornelius

Biology Master’s Theses

Mitochondria are essential organelles for all eukaryotic organisms with very few exceptions. The life-giving processes contributed by mitochondria are the end result of many proteins that are encoded within the mitochondria. Many nuclear encoded proteins give mitochondrial DNA (mtDNA) the high stability needed so that life can thrive.

Saccharomyces cerevisiae (baker's yeast) has historically been a model organism for mitochondrial function studies. These yeast are categorized as facultative anarobes; meaning that they are able to respire or ferment depending on media available. Functional mitochondria allow baker's yeast to thrive on a 3-carbon medium (p+), while mitochondrial dysfunctions due ...