Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2006

Genetics and Genomics

Animal Science Publications

Genetic susceptibility

Articles 1 - 1 of 1

Full-Text Articles in Life Sciences

An Investigation Of Susceptibility To Porcine Reproductive And Respiratory Syndrome Virus Between Two Genetically Diverse Commercial Lines Of Pigs, Amy L. Vincent, Brad J. Thacker, Patrick G. Halbur, Max F. Rothschild, Eileen L. Thacker Jan 2006

An Investigation Of Susceptibility To Porcine Reproductive And Respiratory Syndrome Virus Between Two Genetically Diverse Commercial Lines Of Pigs, Amy L. Vincent, Brad J. Thacker, Patrick G. Halbur, Max F. Rothschild, Eileen L. Thacker

Animal Science Publications

The objective of this study was to determine whether host genetics play a role in susceptibility to the respiratory disease in growing pigs caused by the porcine reproductive and respiratory syndrome virus (PRRSV). Based on a previous study, 2 genetically diverse commercial lines of pigs that also were divergent in the susceptibility of monocyte-derived macrophages to PRRSV infection in vitro were selected for an in vivo challenge study. Based on the average percentage of infected macrophages for each line, a line derived from the Large White breed was characterized as fluorescence-activated cell sortinghi (FACShi), and a line derived ...