Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Animal Science Publications

Quantitative trait loci

Articles 1 - 7 of 7

Full-Text Articles in Life Sciences

The Vertebrate Trait Ontology: A Controlled Vocabulary For The Annotation Of Trait Data Across Species, Carissa A. Park, Susan M. Bello, Cynthia L. Smith, Zhi-Liang Hu, Diane H. Munzenmaier, Rajni Nigam, Jennifer R. Smith, Mary Shimoyama, Janan T. Eppig, James M. Reecy Jan 2013

The Vertebrate Trait Ontology: A Controlled Vocabulary For The Annotation Of Trait Data Across Species, Carissa A. Park, Susan M. Bello, Cynthia L. Smith, Zhi-Liang Hu, Diane H. Munzenmaier, Rajni Nigam, Jennifer R. Smith, Mary Shimoyama, Janan T. Eppig, James M. Reecy

Animal Science Publications

The use of ontologies to standardize biological data and facilitate comparisons among datasets has steadily grown as the complexity and amount of available data have increased. Despite the numerous ontologies available, one area currently lacking a robust ontology is the description of vertebrate traits. A trait is defined as any measurable or observable characteristic pertaining to an organism or any of its substructures. While there are several ontologies to describe entities and processes in phenotypes, diseases, and clinical measurements, one has not been developed for vertebrate traits; the Vertebrate Trait Ontology (VT) was created to fill this void. Significant inconsistencies ...


A Whole Genome Scan For Quantitative Trait Loci For Leg Weakness And Its Related Traits In A Large F2 Intercross Population Between White Duroc And Erhualian, Y. M. Guo, H. S. Ai, J. Ren, G. J. Wang, Y. Wen, H. R. Mao, L. T. Lan, J. W. Ma, B. Brenig, Max F. Rothschild, C. S. Haley, L. S. Huang Jan 2009

A Whole Genome Scan For Quantitative Trait Loci For Leg Weakness And Its Related Traits In A Large F2 Intercross Population Between White Duroc And Erhualian, Y. M. Guo, H. S. Ai, J. Ren, G. J. Wang, Y. Wen, H. R. Mao, L. T. Lan, J. W. Ma, B. Brenig, Max F. Rothschild, C. S. Haley, L. S. Huang

Animal Science Publications

To detect QTL for leg weakness and its related traits in pigs, a total of 1,484 F2 pigs were recorded for leg (at 76 and 213 d) and gait scores (at 153 and 223 d) in a White Duroc × Erhualian intercross. The length and weight of the biceps brachii muscle were measured after slaughter at 240 d. A genome scan was performed with 183 microsatellite markers in the population. A total of 42 QTL were detected, including 16 at the 1% genome-wide significant level and 6 at the 5% genome-wide significant level. Thirty-eight of the 42 QTL showed ...


Genome-Wide Linkage Analysis To Identify Chromosomal Regions Affecting Phenotypic Traits In The Chicken. Iv. Metabolic Traits, H. Zhou, C. M. Evock-Clover, J. P. Mcmurtry, C. M. Ashwell, Susan J. Lamont Jan 2007

Genome-Wide Linkage Analysis To Identify Chromosomal Regions Affecting Phenotypic Traits In The Chicken. Iv. Metabolic Traits, H. Zhou, C. M. Evock-Clover, J. P. Mcmurtry, C. M. Ashwell, Susan J. Lamont

Animal Science Publications

The current study is a comprehensive genome analysis to detect QTL affecting metabolic traits in chickens. Two unique F2 crosses generated from a commercial broiler male line and 2 genetically distinct inbred lines (Leghorn and Fayoumi) were used in the present study. The plasma glucagon, insulin, lactate, glucose, tri-iodothyronine, thyroxine, insulin-like growth factor I, and insulin-like growth factor II concentrations at 8 wk were measured in the 2 F2 crosses. Birds were genotyped for 269 microsatellite markers across the entire genome. The program QTL Express was used for QTL detection. Significance levels were obtained using the permutation test ...


Genome-Wide Linkage Analysis To Identify Chromosomal Regions Affecting Phenotypic Traits In The Chicken. Ii. Body Composition, H. Zhou, C. M. Evock-Clover, J. P. Mcmurtry, C. M. Ashwell, Susan J. Lamont Jan 2007

Genome-Wide Linkage Analysis To Identify Chromosomal Regions Affecting Phenotypic Traits In The Chicken. Ii. Body Composition, H. Zhou, C. M. Evock-Clover, J. P. Mcmurtry, C. M. Ashwell, Susan J. Lamont

Animal Science Publications

The current study is a comprehensive genome analysis to detect QTL affecting metabolic traits in chickens. Two unique F2 crosses generated from a commercial broiler male line and 2 genetically distinct inbred lines (Leghorn and Fayoumi) were used in the present study. The plasma glucagon, insulin, lactate, glucose, tri-iodothyronine, thyroxine, insulin-like growth factor I, and insulin-like growth factor II concentrations at 8 wk were measured in the 2 F2 crosses. Birds were genotyped for 269 microsatellite markers across the entire genome. The program QTL Express was used for QTL detection. Significance levels were obtained using the permutation test ...


Genome-Wide Linkage Analysis To Identify Chromosomal Regions Affecting Phenotypic Traits In The Chicken. I. Growth And Average Daily Gain, H. Zhou, Nader Deeb, C. M. Evock-Clover, C. M. Ashwell, Susan J. Lamont Jan 2006

Genome-Wide Linkage Analysis To Identify Chromosomal Regions Affecting Phenotypic Traits In The Chicken. I. Growth And Average Daily Gain, H. Zhou, Nader Deeb, C. M. Evock-Clover, C. M. Ashwell, Susan J. Lamont

Animal Science Publications

Two informative chicken F2 populations based on crosses between a broiler breeder male line and dams from genetically distinct, highly inbred (>99%) chicken lines, the Leghorn G-B2 and Fayoumi M15.2, have been used for genome-wide linkage and QTL analysis. Phenotypic data on 12 body composition traits (breast muscle weight, breast muscle weight percentage, abdominal fat weight, abdominal fat weight percentage, heart weight, heart weight percentage, liver weight, liver weight percentage, spleen weight, spleen weight percentage, and drumstick weight, and drumstick weight percentage) were collected. Birds were genotyped for 269 microsatellite markers across the genome. The QTL Express program ...


Chicken Quantitative Trait Lloci For Growth And Body Composition Associated With The Very Low Density Apolipoprotein-Ii Gene, H. Li, Nader Deeb, H. Zhou, C. M. Ashwell, Susan J. Lamont Jan 2005

Chicken Quantitative Trait Lloci For Growth And Body Composition Associated With The Very Low Density Apolipoprotein-Ii Gene, H. Li, Nader Deeb, H. Zhou, C. M. Ashwell, Susan J. Lamont

Animal Science Publications

Very low density apolipoprotein-II (apoVLDL-II) is a major constituent of very low density lipoprotein and is involved in lipid transportation in chickens. The current study was designed to investigate the associations of an apoVLDL-II gene polymorphism on chicken growth and body composition traits. The Iowa Growth and Composition Resource Population was established by crossing broiler sires with dams from 2 unrelated highly inbred lines (Leghorn and Fayoumi). The F1 birds were intercrossed, within dam line, to produce 2 related F2 populations. Body weight and body composition traits were measured in the F2 population. Primers for the 5'-flanking region in ...


Microsatellite Markers Associated With Resistance To Marek’S Disease In Commercial Layer Chickens, Joseph Paul Mcelroy, Jack C. Dekkers, J. E. Fulton, Neil P. O'Sullivan, M. Soller, E. Lipkin, W. Zhang, Kenneth J. Koehler, Susan J. Lamont, H. H. Cheng Jan 2005

Microsatellite Markers Associated With Resistance To Marek’S Disease In Commercial Layer Chickens, Joseph Paul Mcelroy, Jack C. Dekkers, J. E. Fulton, Neil P. O'Sullivan, M. Soller, E. Lipkin, W. Zhang, Kenneth J. Koehler, Susan J. Lamont, H. H. Cheng

Animal Science Publications

The objective of the current study was to identify QTL conferring resistance to Marek's disease (MD) in commercial layer chickens. To generate the resource population, 2 partially inbred lines that differed in MD-caused mortality were intermated to produce 5 backcross families. Vaccinated chicks were challenged with very virulent plus (vv+) MD virus strain 648A at 6 d and monitored for MD symptoms. A recent field isolate of the MD virus was used because the lines were resistant to commonly used older laboratory strains. Selective genotyping was employed using 81 microsatellites selected based on prior results with selective DNA pooling ...