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Full-Text Articles in Life Sciences

The Development And Use Of Computational Tools In Forensic Science, Dennis E. Slice Jul 2019

The Development And Use Of Computational Tools In Forensic Science, Dennis E. Slice

Human Biology Open Access Pre-Prints

Modern computational resources make available a rich toolkit of statistical methods that can be applied to forensic questions. This toolkit is built on the foundation of statistical developments dating back to the 19th century. To fully and effectively exploit these developments, both the makers and users of software must be keenly aware of the quality, i.e., the accuracy and precision, of the data being modeled or analyzed, and end-users must be sufficiently familiar with the underlying theory to understand the process and results of any analysis or software they use. This is especially important for medico-legal personnel who might ...


Probability, Populations, Phylogenetics And Hominin Speciation, Niccolo Caldararo Jul 2019

Probability, Populations, Phylogenetics And Hominin Speciation, Niccolo Caldararo

Human Biology Open Access Pre-Prints

A number of recent articles have appeared on the hominin Denisova fossil remains. Many of them focus on attempts to produce DNA sequences from the extracted samples. Often these project mtDNA sequences from the fossil remains of a number of Neandertal fossils and the Denisovans in an attempt to understand the evolution of Mid Pleistocene human ancestors. These papers, introduce a number of problems in the interpretation of speciation in hominins. One concerns the degradation of the ancient DNA and its interpretation as authentic genetic information. Another concerns the idea of “species” versus that of “population” and the use of ...


The Controversy Of Sexual Violence In The University Setting: Are College Athletes Given A Lighter Sentence Due To Their “Status”, Emma Weber Apr 2019

The Controversy Of Sexual Violence In The University Setting: Are College Athletes Given A Lighter Sentence Due To Their “Status”, Emma Weber

Honors College Theses

The following paper investigates sexual violence on university campuses. It discusses the role of the Title IX of the Education Amendments of 1972 along with a Dear Colleague Letter enacted by the United States’ federal government to all public institutions regarding how to respond when complaints and allegations of sexual violence are made. The paper addresses the statistics and common misconceptions surrounding sexual violence on college campuses before focusing specifically on student-athletes’ involvement in sexually violent crimes. It then looks into three highly publicized cases where student-athletes are the alleged perpetrators of sexual violence. The three cases analyzed are: the ...


Oxygen And Hydrogen Isotopes In Human Hair And Tap Water: Modeling Relationships In A Modern Mexican Population, Chelsey A. Juarez, Robin Ramey, David T. Flaherty, Belinda Akpa Apr 2019

Oxygen And Hydrogen Isotopes In Human Hair And Tap Water: Modeling Relationships In A Modern Mexican Population, Chelsey A. Juarez, Robin Ramey, David T. Flaherty, Belinda Akpa

Human Biology Open Access Pre-Prints

This study investigates the relationship between O and H isotopes in samples of Mexican hair and drinking water. The purpose of this study was twofold. First, we wanted to quantify the relationship between isotopes in Mexican hair and tap water to understand the impact of water stress and differing socioeconomic status on accurate predictions of drinking water. Second, we wanted to determine whether currently existing semi mechanistic models could accurately represent the relationship between hair and tap water. For this study, we used a subset of paired (N = 62) human hair and (N = 76) tap water samples. Isotope values in ...


Age-At-Death Estimation For Modern Populations In Mexico And Puerto Rico Through The Use Of 3d Laser Scans Of The Pubic Symphysis, Cristina Figueroa Soto, Bridget F.B. Algee-Hewitt, Guillermo Bravo Morante, Dennis E. Slice, Dawnie W. Steadman Apr 2019

Age-At-Death Estimation For Modern Populations In Mexico And Puerto Rico Through The Use Of 3d Laser Scans Of The Pubic Symphysis, Cristina Figueroa Soto, Bridget F.B. Algee-Hewitt, Guillermo Bravo Morante, Dennis E. Slice, Dawnie W. Steadman

Human Biology Open Access Pre-Prints

Reliable age-at-death estimates from the adult skeleton is of fundamental importance in forensic anthropology, as it contributes to the identity parameters used in a medico-legal death investigation. However, reliable estimates are made difficult by the fact that many traditional aging methods are dependent upon a set of population-specific criteria derived from individuals of European and African descent. The absence of information on the potential differences in the aging patterns of underrepresented, especially Hispanic populations, may hinder our efforts to produce useful age-at-death estimates. In response to these concerns, this study explores the utility of currently available aging techniques, and explores ...


Population Identifiability From Forensic Genetic Markers: Ancestry Variation In Latin America, Cris E. Hughes, Bridget F.B. Algee-Hewitt, Lyle Konigsberg Apr 2019

Population Identifiability From Forensic Genetic Markers: Ancestry Variation In Latin America, Cris E. Hughes, Bridget F.B. Algee-Hewitt, Lyle Konigsberg

Human Biology Open Access Pre-Prints

The Combined DNA Index System (CODIS) loci are a standard microsatellite marker set widely used for distinguishing among individuals in forensic DNA identity testing for medico-legal casework in the United States and in other countries. In anthropological genetic research, CODIS markers have become an important tool for uses extending beyond case investigations to quantify ancestry proportions, reveals patterns of admixture and trace population histories. These investigations are especially prevalent in studies of Latin American population structure. Nevertheless, the accuracy of the ancestry estimates computed from the CODIS loci for highly admixed Latino populations has not been formally tested. Long-standing arguments ...


Neanderthal And Woolly Mammoth Molecular Resemblance: Genetic Similarities Might Underlie Cold Adaptation Suite, Meidad Kislev, Ran Barkai Apr 2019

Neanderthal And Woolly Mammoth Molecular Resemblance: Genetic Similarities Might Underlie Cold Adaptation Suite, Meidad Kislev, Ran Barkai

Human Biology Open Access Pre-Prints

With the ongoing growth of gene-based research in recent decades, the possibility of examining changes that have taken place in structures over the course of evolution has become increasingly accessible. One intriguing subject at the forefront of evolutionary research is that of how environmental pressures affect species evolution through epigenetic adaptation. In this paper we present the available molecular components of adaptation to cold environments in two extinct mammals – the woolly mammoth and the Neanderthal. These two species co-existed in similar geographic and environmental European settings during the Middle and Upper Pleistocene and both were direct descendants of African ancestors ...


Thinking Computationally About Forensics: Anthropological Perspectives On Advancements In Technologies, Data, And Algorithms, Bridget F.B. Algee-Hewitt, Jieun Kim, Cris E. Hughes Nov 2018

Thinking Computationally About Forensics: Anthropological Perspectives On Advancements In Technologies, Data, And Algorithms, Bridget F.B. Algee-Hewitt, Jieun Kim, Cris E. Hughes

Human Biology Open Access Pre-Prints

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Who Needs Data? I’Ve Got Experience!, Dawnie Wolfe Steadman Nov 2018

Who Needs Data? I’Ve Got Experience!, Dawnie Wolfe Steadman

Human Biology Open Access Pre-Prints

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New Approaches To Juvenile Age Estimation In Forensics: Application Of Transition Analysis Via The Shackelford Et Al. Method To A Diverse Modern Subadult Sample, Kelly R. Kamnikar, Nicholas P. Herrmann, Amber M. Plemons Nov 2018

New Approaches To Juvenile Age Estimation In Forensics: Application Of Transition Analysis Via The Shackelford Et Al. Method To A Diverse Modern Subadult Sample, Kelly R. Kamnikar, Nicholas P. Herrmann, Amber M. Plemons

Human Biology Open Access Pre-Prints

Dental development is one of the most widely utilized and accurate methods available for estimating age in subadult skeletal remains. The timing of tooth growth and development is regulated by genetics and less affected by external factors, allowing reliable estimates of chronological age. Traditional methodology focuses on comparing tooth developmental scores to corresponding age charts. Using the Moorrees, Fanning, and Hunt (MFH) developmental scores, Shackelford and colleagues embed the dental development method in a statistical framework based on transition analysis. They generated numerical parameters underlining each “stage” and age-at-death distribution and applied them to fossil hominins and Neanderthals with limited ...


Open-Source Tools For Dense Facial Tissue Depth Mapping (Ftdm) Of Computed Tomography Models, Terrie Simmons-Ehrhardt, Catyana Falsetti, Anthony B. Falsetti, Christopher J. Ehrhardt Aug 2018

Open-Source Tools For Dense Facial Tissue Depth Mapping (Ftdm) Of Computed Tomography Models, Terrie Simmons-Ehrhardt, Catyana Falsetti, Anthony B. Falsetti, Christopher J. Ehrhardt

Human Biology Open Access Pre-Prints

Computed tomography (CT) scans provide anthropologists with a resource to generate three- dimensional (3D) digital skeletal material to expand quantification methods and build more standardized reference collections. The ability to visualize and manipulate the bone and skin of the face simultaneously in a 3D digital environment introduces a new way for forensic facial approximation practitioners to access and study the face. Craniofacial relationships can be quantified with landmarks or with surface processing software that can quantify the geometric properties of the entire 3D facial surface. This paper describes tools for the generation of dense facial tissue depth maps (FTDMs) using ...


Of Typicality And Predictive Distributions In Discriminant Function Analysis, Lyle W. Konigsberg, Susan R. Frankenberg Aug 2018

Of Typicality And Predictive Distributions In Discriminant Function Analysis, Lyle W. Konigsberg, Susan R. Frankenberg

Human Biology Open Access Pre-Prints

While discriminant function analysis is an inherently Bayesian method, researchers attempting to estimate ancestry in human skeletal samples often follow discriminant function analysis with the calculation of frequentist-based typicalities for assigning group membership. Such an approach is problematic in that it fails to account for admixture and for variation in why individuals may be classified as outliers, or non-members of particular groups. This paper presents an argument and methodology for employing a fully Bayesian approach in discriminant function analysis applied to cases of ancestry estimation. The approach requires adding the calculation, or estimation, of predictive distributions as the final step ...


Digital Tools For Managing Different Steps Of The Systematic Review Process, Wendy Wu, Katherine Akers, Ella Hu, Alexandra Sarkozy, Patricia Vinson May 2018

Digital Tools For Managing Different Steps Of The Systematic Review Process, Wendy Wu, Katherine Akers, Ella Hu, Alexandra Sarkozy, Patricia Vinson

Library Scholarly Publications

Performing systematic reviews (SR) and meta-analyses is an arduous and time-consuming process that involves not only comprehensive literature searching but also record de-duplication, title/abstract and full-text screening, data extraction, quality assessment, statistical analysis, data visualization, report writing, and the creation of a bibliography. In the past several years, several digital tools and software have become available to facilitate different steps of the systematic review process. However, due to the growing number of tools, it can be difficult for systematic reviewers to make fully informed decisions about which tool(s) to use. Here, we (1) compile a comprehensive list of ...


Exploring The Short-Term Effects Of Probiotic And Prebiotic Supplementation On The Microbiota And Physiology Of Male C57bl/6 Mice, Miguel Angel Rivas Jan 2018

Exploring The Short-Term Effects Of Probiotic And Prebiotic Supplementation On The Microbiota And Physiology Of Male C57bl/6 Mice, Miguel Angel Rivas

Wayne State University Theses

The gut microbiome may play a role in the development of chronic diseases like obesity, diabetes, and heart disease. Diets including prebiotics or probiotics can alter the abundance of gut bacterial groups and have subsequent health effects. In this study we wanted to establish a method for comparing the benefits of commercial supplements that alter the microbiota by monitoring fecal microbial profiles in male C57BL/6 mice (n = 24) exposed to 15 days of dietary supplementation. A probiotic diet (VSL#3) and a prebiotic diet (potato starch) were compared to a standard diet (n = 8 for each group). Microbial profiles ...


African-American Collegiate Women's Perception And Participation In Physical Activity, Lauren Courtney Scott Jan 2018

African-American Collegiate Women's Perception And Participation In Physical Activity, Lauren Courtney Scott

Wayne State University Dissertations

ABSTRACT

AA COLLEGE WOMEN’’S PERCEPTION AND

PARTICIPATION IN PHYSICAL ACTIVITY

by

LAUREN SCOTT

March 2018

Advisor: Dr. Bo Shen

Major: Kinesiology

Degree: Doctor of Philosophy

Overview: In the United States, adult engagement in physical inactivity has decreased since the implementation of the 2008 PA guidelines. In 2013, only 20% of Americans met the PA recommendations. In 2014, research showed that 23% of adults did not engage in any leisure PA in the United States (U.S Department of Health and Human Services, 2016). In general, females were found to be less active than males from youth through adulthood (Matthews ...


Mitochondrial Dna Analysis Of Mazahua And Otomi Indigenous Populations From Estado De Mexico Suggests A Distant Common Ancestry, Angelica GonzáLez-Oliver, Ernesto Garfias-Morales, D G. Smith, Mirsha Quinto-Sánchez Jan 2018

Mitochondrial Dna Analysis Of Mazahua And Otomi Indigenous Populations From Estado De Mexico Suggests A Distant Common Ancestry, Angelica GonzáLez-Oliver, Ernesto Garfias-Morales, D G. Smith, Mirsha Quinto-Sánchez

Human Biology Open Access Pre-Prints

The indigenous Mazahua and Otomi have inhabited the same localities in Estado de Mexico since pre-Columbian times. Their languages, Mazahua and Otomi, belong to the Otomanguean linguistic family, and, while they share cultural traditions and a regional history that suggest close genetic relationships and common ancestry, the historical records concerning their origin are confusing. To understand the biological relationships between Mazahua and Otomi we analyzed the mitochondrial DNA (mtDNA) genetic variation. We identified the mtDNA haplogroups by restriction fragment length polymorphism typing and sequenced the hypervariable region I of the mtDNA control region in 141 Mazahua and 100 Otomi. These ...


Investigation Of The Saccharomyces Cerevisiae Gpi Transamidase: Insights Into Its Activity And Subunit-Subunit Interactions, Travis Ness Jan 2018

Investigation Of The Saccharomyces Cerevisiae Gpi Transamidase: Insights Into Its Activity And Subunit-Subunit Interactions, Travis Ness

Wayne State University Dissertations

Glycosylphosphatidylinositol (GPI) anchoring of proteins is a eukaryotic, posttranslational

modification catalyzed by GPI transamidase (GPI-T). The Saccharomyces

cerevisiae GPI-T is composed of five membrane-bound subunits: Gaa1, Gpi8, Gpi16,

Gpi17, and Gab1. Structural and functional studies have been hindered by the

complexity of this enzyme. Conditions to purify the Gpi8:Gaa1:Gpi16 GPI-T heterotrimer

from yeast have been reported, but an understanding of the subunit functions,

interactions, and stoichiometry remain unclear. Furthermore, a reliable, quantitative, in

vitro assay for this important post-translational modification has remained elusive for

nearly three decades.

Our laboratory has developed an in vitro peptide cleavage assay that ...


Appropriate Preconditioning Of The Uterine Endoplasmic Reticulum Stress Response Inhibits Preterm Labor, Judith Ann Ingles Jan 2018

Appropriate Preconditioning Of The Uterine Endoplasmic Reticulum Stress Response Inhibits Preterm Labor, Judith Ann Ingles

Wayne State University Dissertations

Introduction: In this study, we are testing the overarching hypothesis that preconditioning the myometrial UPR allows for the maintenance of non-apoptotic CASP3 activity and thus sustains uterine quiescence. We have previously demonstrated that the pregnant uterus facilitates uterine quiescence through UPR mediated activation of non-apoptotic CASP3, yet the mechanism in which CASP3 utilizes to avoid its apoptotic cell fate is unresolved. There is a growing body of evidence including our own that demonstrates remote and direct preconditioning with minor stresses propagates cytoprotective mechanisms that allow for the avoidance of apoptotic cell death upon exposure to a subsequent more damaging stress ...


Inflammation In The Pathogenesis Of Diabetic Retinopathy, Haoshen Shi Jan 2018

Inflammation In The Pathogenesis Of Diabetic Retinopathy, Haoshen Shi

Wayne State University Dissertations

The general purpose of these studies is to investigate inflammation in diabetic retinopathy in an effort to identify key intervention points to develop as treatments. Firstly, we showed that the neuropeptide VIP displayed protective immunoregulatory effects on retinal endothelial cells cultured under high glucose conditions. This effect was carried out, in part through the VPAC2 receptor.

Next, we studied the β-adrenergic receptor agonist, Compound 49b, and its effect on the pro-resolving RvD1 pathway. Compound 49b was previously shown to suppress both inflammatory and apoptotic responses in DR. We demonstrated that Compound 49b rescued the high glucose-induced decrese in RvD1 and ...


Missing Heritability And Novel Germline Risk Loci In Hereditary Ovarian Cancer: Insights From Whole Exome Sequencing And Functional Analyses, Jaime Lyn Stafford Jan 2018

Missing Heritability And Novel Germline Risk Loci In Hereditary Ovarian Cancer: Insights From Whole Exome Sequencing And Functional Analyses, Jaime Lyn Stafford

Wayne State University Dissertations

While 25% of ovarian cancer (OVCA) cases are due to inherited factors, most of the genetic risk remains unexplained. This study addressed this gap by identifying previously undescribed OVCA risk loci through the whole exome sequencing (WES) of 48 BRCA1/BRCA2 wild type women diagnosed with OVCA, selected for high risk of genetic inheritance. Five clearly pathogenic variants were identified in this sample, four of which are in two genes featured on current multi-gene panels; (RAD51D, ATM). In addition, a high impact variant in FANCM (R1931*) was identified. FANCM has been recently implicated in familial breast cancer risk but is ...


Role Of Sirna Pathway In Epigenetic Modifications Of The Drosophila Melanogaster X Chromosome, Nikita Deshpande Jan 2018

Role Of Sirna Pathway In Epigenetic Modifications Of The Drosophila Melanogaster X Chromosome, Nikita Deshpande

Wayne State University Dissertations

Eukaryotic genomes are organized into large domains of coordinated regulation. The role of small RNAs in formation of these domains is largely unexplored. An extraordinary example of domain-wide regulation is X chromosome compensation in Drosophila melanogaster males. This process occurs by hypertranscription of genes on the single male X chromosome. Extensive research in this field has shown that the Male Specific Lethal (MSL) complex binds X-linked genes and modifies chromatin to increase expression. The components of this complex, and their actions on chromatin, are well studied. In contrast, the mechanism that results in exclusive recruitment to the X chromosome is ...


Alternative Strategies To Inhibit Lysine Methyltransferases And Deubiquitinases In Human Cancers, Nicholas Spellmon Jan 2018

Alternative Strategies To Inhibit Lysine Methyltransferases And Deubiquitinases In Human Cancers, Nicholas Spellmon

Wayne State University Dissertations

X-ray crystallography is the gold standard method for imagining macromolecules to atomic resolution. Three dimensional data is central to understanding the molecular mechanism how DNA, RNA and proteins function in biological events. Structural insights into these events provide a molecular window to visualize how biological molecules influence human health. Visualizing the architecture of these molecules set the stage for rational and selective drug design. The following dissertation utilizes biochemical and biophysical tools, including X-ray crystallography, to shed light on poorly understood mechanisms related to SMYD2 activity and regulation, USP10 architecture and function, and PDZ-RhoGEF dimerization. SMYD2 is one member of ...


Evaluating Nubian Population Structure From Cranial Nonmetric Traits: Gene Flow, Genetic Drift, And Population History Of The Nubian Nile Valle, Kanya Godde, Richard L. Jantz Jan 2018

Evaluating Nubian Population Structure From Cranial Nonmetric Traits: Gene Flow, Genetic Drift, And Population History Of The Nubian Nile Valle, Kanya Godde, Richard L. Jantz

Human Biology Open Access Pre-Prints

Paleolithic archaeological and skeletal remains from the Nile Valley have yielded a complex picture of life along the river. Sociocultural and sociopolitical events during this timeframe shaped population structure, while gene flow and genetic drift further developed it. In this paper, we take a population genetics approach to modeling Nubian biological relationships in an effort to describe how an accumulation of events formed Nubian population structure. A variety of Nubian samples were utilized, spanning the Mesolithic-Christian time periods, and geographically, from just above the first through the third cataracts. Population genetics statistics were employed to estimate and depict biological affinities ...


Sensitivity Of Quagga Mussels (Dreissena Rostriformis Bugensis) To Cyanobacteria At Multiple Life History Stages, Anna Boegehold Jan 2018

Sensitivity Of Quagga Mussels (Dreissena Rostriformis Bugensis) To Cyanobacteria At Multiple Life History Stages, Anna Boegehold

Wayne State University Dissertations

Quagga mussels (Dreissena rostriformis bugensis) originate from brackish waters of the Ponto-Caspian area and are nuisance invasive species in North American and European freshwaters. Their invasion has caused major economic and ecological damages in the Laurentian Great Lakes. Through selective filter feeding, quagga mussels have promoted the growth of cyanobacteria. Harmful cyanobacteria blooms have the potential to produce toxins, which can be toxic to humans and wildlife. Although quagga mussels can increase the prevalence of cyanobacteria blooms, it is unknown how they are physiologically affected by cyanobacteria and understanding these dynamics can be useful in the management of this invasive ...


Design, Synthesis, And Reactivity Of Homo- And Heterobimetallic Complexes Bridged By A Xanthene Linker, Thilini Samangi Hollingsworth Jan 2018

Design, Synthesis, And Reactivity Of Homo- And Heterobimetallic Complexes Bridged By A Xanthene Linker, Thilini Samangi Hollingsworth

Wayne State University Dissertations

Cooperative reactivity of bimettalics can be is observed in many different areas of chemistry and have been increasingly investigated because of the advantageous reactivity when compared to the corresponding mononuclear systems. The focus of my dissertation is on (1) investigation of the homobimetallic cooperativity in lactide polymerization catalysis; (2) investigation of the heterobimetallic cooperativity in the biomimetic studies of Mo-Cu carbon monoxide dehydrogenase (CODH) enzyme in order to make a functional model of its active site.

Three new main group bis(alkoxide) complexes Mg(OR)2(THF)2, Zn(Cl)(μ2-OR)2Li(THF) and In(OR)2(μ2-Cl)2Li(THF ...


The Role Of Alström Syndrome 1 (Alms1) In Hypertension, Salt Sensitivity And Metabolic Syndrome, Keyona Nicole King-Medina Jan 2018

The Role Of Alström Syndrome 1 (Alms1) In Hypertension, Salt Sensitivity And Metabolic Syndrome, Keyona Nicole King-Medina

Wayne State University Dissertations

In humans, inactivating mutations in the Alström syndrome 1 (ALMS1) gene cause obesity, insulin resistance and hypertension (metabolic syndrome). More so, SNPs in the ALMS1 gene have been associated with kidney disease and cardiovascular disease. The

mechanisms causing these alterations are unclear. We recently found that the ALMS1 is expressed in the kidney thick ascending limb (TAL) where it mediates endocytosis of the renal Na/K/2Cl cotransporter termed NKCC2. To study the role of ALMS1 in renal

physiology we generated ALMS1 knockout (KO) rats in a Dahl salt-sensitive genetic background via zinc-finger nuclease targeting. We previously found that the ...


The Effect Of Treadmill Vs. Nustep Recumbent Cross Trainer On Gait And Lower Extremity Electromyography After Chronic Stroke, Nicholas Joseph Siekirk Jan 2018

The Effect Of Treadmill Vs. Nustep Recumbent Cross Trainer On Gait And Lower Extremity Electromyography After Chronic Stroke, Nicholas Joseph Siekirk

Wayne State University Dissertations

Pilot Part 1: The purpose was to investigate the effect of a perceived exertion based cadence on lower extremity muscle activation, as measured by surface electromyography (EMG) on a recumbent cross trainer. The purpose of this investigation was to study the EMG activity of 12 lower extremity muscles during five different stepping protocols; perceived exertion based self-selected (SS) cadence with level 1 resistance (SSL1), SS cadence with level 8 resistance (SSL8), +20% SS cadence (SS+20), -20% SS cadence (SS-20), and at a set 80 steps per minute at resistance level 1 (80L1). In order to determine SS cadence each ...


The Relationship Between Knowledge, Attitudes, And Behaviors Regarding Eco-Justice Issues Among Middle And High School Students In Eco-Schools In Puerto Rico, Elsie Aquino Jan 2018

The Relationship Between Knowledge, Attitudes, And Behaviors Regarding Eco-Justice Issues Among Middle And High School Students In Eco-Schools In Puerto Rico, Elsie Aquino

Wayne State University Dissertations

The conservation, preservation, and protection of the environment are responsibilities that must be globally shared by human beings to “meet the needs of the present without compromising the ability of future generations to meet their own needs” (World Commission on Environment and Development (WCED, 1987, p. 43). When citizens acquire the knowledge and skills needed to become agents of change, the lack of interconnectedness – a relationship to nature as one of dominion and control – that presently exists between humans and nature might subside (Winograd, 2016). Through the re-orientation of the present educational system and the development of curricula that addresses ...


A Motivational Climate Intervention And Exercise-Related Outcomes: A Longitudinal Perspective, Theresa C. Brown, Mary D. Fry, E. Whitney Moore Dec 2017

A Motivational Climate Intervention And Exercise-Related Outcomes: A Longitudinal Perspective, Theresa C. Brown, Mary D. Fry, E. Whitney Moore

Kinesiology, Health and Sport Studies

While researchers have suggested that the social context in exercise settings is linked to individuals’ physical activity motivation and potential exercise-related outcomes, few research designs have examined the nuance of those relationships. Moreover, interventions targeting the social context of exercise settings are sparse, so the potential impact of staff training on members’ motivation to exercise are not well known. Drawing from two major motivation theories, achievement goal perspective theory and self-determination theory, this study considered an intervention with fitness center staff from the members’ perspectives. Members completed a survey before and after an intervention designed to help staff create a ...


Chaco Canyon Dig Unearths Ethical Concerns, Katrina G. Claw, Dorothy Lippert, Jessica Bardill, Anna Cordova, Keolu Fox, Joseph M. Yracheta, Alyssa C. Bader, Deborah A. Bolnick, Ripan S. Malhi, Kimberly Tallbear, Nanibaa' A. Garrison Nov 2017

Chaco Canyon Dig Unearths Ethical Concerns, Katrina G. Claw, Dorothy Lippert, Jessica Bardill, Anna Cordova, Keolu Fox, Joseph M. Yracheta, Alyssa C. Bader, Deborah A. Bolnick, Ripan S. Malhi, Kimberly Tallbear, Nanibaa' A. Garrison

Human Biology Open Access Pre-Prints

The field of paleogenomics (the study of ancient genomes) is rapidly advancing with more robust methods of isolating ancient DNA and increasing access to next-generation DNA sequencing technology. As these studies progress, many important ethical issues have emerged that should be considered when ancient Native American remains, whom we refer to as ancestors, are used in research. We highlight a recent article by Kennett et al. (2017), “Archaeogenomic evidence reveals prehistoric matrilineal dynasty,” that brings several ethical issues to light that should be addressed in paleogenomics research (Kennett et al. 2017). The study helps elucidate the matrilineal relationships in ancient ...