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University of Nebraska - Lincoln

Dissertations, Theses, & Student Research in Food Science and Technology

Adherence

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Full-Text Articles in Life Sciences

Adherence Inhibition Of Human Pathogens Campylobacter Jejuni And Campylobacter Coli By Non-Digestible Oligosaccharides, Alejandra Ramirez-Hernandez Jul 2014

Adherence Inhibition Of Human Pathogens Campylobacter Jejuni And Campylobacter Coli By Non-Digestible Oligosaccharides, Alejandra Ramirez-Hernandez

Dissertations, Theses, & Student Research in Food Science and Technology

Adherence is the first and one of the most important steps of bacterial pathogenesis. Natural derived components that inhibit the adherence of pathogens to the surface of epithelial cells have received considered interest. The goal of this research was to assess the anti-adherence activity of mannan oligosaccharides (MOS), pectic oligosaccharides (POS) and cranberry high molecular weight component (HMW) against Campylobacter jejuni and Campylobacter coli. First the anti-adherence activity of MOS and their purified fraction (pMOS) was tested against three strains of C. jejuni and two strains of C. coli. Results shown significant reductions in adherence (up to 70%) of all ...


Non-Digestible Oligosaccharides: Anti-Adherence And Other Biological Properties, Maria I. Quintero-Villegas Jul 2014

Non-Digestible Oligosaccharides: Anti-Adherence And Other Biological Properties, Maria I. Quintero-Villegas

Dissertations, Theses, & Student Research in Food Science and Technology

Bacterial adherence is the first and one of the most important steps in bacterial pathogenesis. Adherence to host cell surfaces requires that the bacteria recognize specific receptors in the surface of epithelial cells. Therefore, agents that act as molecular decoys to interfere with adherence could be useful prophylactic treatments to prevent or mitigate the onset of infections. The goal of this research was to assess the ability of several food grade non-digestible oligosaccharides (NDOs) to act as molecular decoys and prevent bacterial adherence in vitro as well as in vivo. First, the antiadherence effect of specific species chitooligosaccharides (CHOS) at ...