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2003

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Articles 1 - 27 of 27

Full-Text Articles in Life Sciences

Fisheries In Sundarbans: Problems And Prospects, Ganesh Chandra, R L. Sagar Dec 2003

Fisheries In Sundarbans: Problems And Prospects, Ganesh Chandra, R L. Sagar

Ganesh Chandra

Sundarbans, the largest delta on the planet earth is famous for its marine and estuarine fish resources. A large population is dependent on fishery activity and capture fisheries is treated as the backbone of Sundarban economy. Sundarban boast around 172 species of fishes, 20 species of prawn and 44 species of crabs including two edible crabs. But fisheries in Sundarbans faces some difficult problems which have an impact on the biodiversity, sustainability and livelihood of fish resources and fisher folk viz. shrinking tiger prawn population, indiscriminate fish seed collection, lack of post harvest and other infrastructures, natural calamities such as ...


Quality Control And Peak Finding For Proteomics Data Collected From Nipple Aspirate Fluid Using Surface Enhanced Laser Desorption And Ionization., Jeffrey S. Morris, Kevin R. Coombes, Herbert A. Fritsche, Charlotte Clarke, Jeng-Neng Chen, Keith A. Baggerly, Lian-Chun Xiao, Mien-Chie Hung, Henry M. Kuerer Oct 2003

Quality Control And Peak Finding For Proteomics Data Collected From Nipple Aspirate Fluid Using Surface Enhanced Laser Desorption And Ionization., Jeffrey S. Morris, Kevin R. Coombes, Herbert A. Fritsche, Charlotte Clarke, Jeng-Neng Chen, Keith A. Baggerly, Lian-Chun Xiao, Mien-Chie Hung, Henry M. Kuerer

Jeffrey S. Morris

Background: Recently, researchers have been using mass spectroscopy to study cancer. For use of proteomics spectra in a clinical setting, stringent quality-control procedures will be needed.

Methods: We pooled samples of nipple aspirate fluid from healthy breasts and breasts with cancer to prepare a control sample. Aliquots of the control sample were used on two spots on each of three IMAC ProteinChip® arrays (Ciphergen Biosystems, Inc.) on 4 successive days to generate 24 SELDI spectra. In 36 subsequent experiments, the control sample was applied to two spots of each ProteinChip array, and the resulting spectra were analyzed to determine how ...


Does Landscape Diversity Slow The Spread Of Rotation-Resistant Western Corn Rootworm (Coleoptera: Chrysomelidae)?, D. W. Onstad, D. W. Crwoder, S. A. Isard, E. Levine, J. L. Spencer, Matthew E. O'Neal, S. T. Ratcliffe, M. E. Gray, L. W. Bledsoe, C. D. Di Fonzo, J. B. Eisley, C. R. Edwards Oct 2003

Does Landscape Diversity Slow The Spread Of Rotation-Resistant Western Corn Rootworm (Coleoptera: Chrysomelidae)?, D. W. Onstad, D. W. Crwoder, S. A. Isard, E. Levine, J. L. Spencer, Matthew E. O'Neal, S. T. Ratcliffe, M. E. Gray, L. W. Bledsoe, C. D. Di Fonzo, J. B. Eisley, C. R. Edwards

Matthew E. O'Neal

A behavioral change in some western corn rootworm (Diabrotica virgifera virgifera LeConte) populations is threatening the effectiveness of crop rotation, a successful management strategy for controlling this pest. We created a set of simple meteorologic and behavioral models that can be used to predict the spread of the beetle infesting soybean (Glycine max (L.)) throughout the midwestern United States. We used data collected in Illinois, IN, MI, and Ohio to create maps of observations to evaluate the model. We displayed data on the maps using detection thresholds for western corn rootworm in soybean fields of 10 or 20 beetles per ...


Sensitization Of Staphylococcus Aureus And Escherichia Coli To Antibiotics By The Sesquiterpenoids Nerolidol, Farnesol, Bisabolol, And Apritone, Byron F. Brehm-Stecher, Eric A. Johnson Oct 2003

Sensitization Of Staphylococcus Aureus And Escherichia Coli To Antibiotics By The Sesquiterpenoids Nerolidol, Farnesol, Bisabolol, And Apritone, Byron F. Brehm-Stecher, Eric A. Johnson

Byron F. Brehm-Stecher

The sesquiterpenoids nerolidol, farnesol, bisabolol, and apritone were investigated for their abilities to enhance bacterial permeability and susceptibility to exogenous antimicrobial compounds. Initially, it was observed by flow cytometry that these sesquiterpenoids promoted the intracellular accumulation of the membrane-impermeant nucleic acid stain ethidium bromide by live cells of Lactobacillus fermentum, suggesting that enhanced permeability resulted from disruption of the cytoplasmic membrane. The ability of these sesquiterpenoids to increase bacterial susceptibility to a number of clinically important antibiotics was then investigated. In disk diffusion assays, treatment with low concentrations (0.5 to 2 mM) of nerolidol, bisabolol, or apritone enhanced the ...


Genome-Wide Scan For Quantitative Trait Loci Influencing Ldl Size And Plasma Triglyceride In Familial Hypertriglyceridemia, Melissa A. Austin, Karen L. Edwards, Stephanie A. Monks, Kent M. Koprowicz, John D. Brunzell, Arno G. Motulsky, Michael C. Mahaney, James E. Hixson Aug 2003

Genome-Wide Scan For Quantitative Trait Loci Influencing Ldl Size And Plasma Triglyceride In Familial Hypertriglyceridemia, Melissa A. Austin, Karen L. Edwards, Stephanie A. Monks, Kent M. Koprowicz, John D. Brunzell, Arno G. Motulsky, Michael C. Mahaney, James E. Hixson

Kent M Koprowicz

No abstract provided.


A Comprehensive Approach To The Analysis Of Maldi-Tof Proteomics Spectra From Serum Samples., Keith A. Baggerly, Jeffrey S. Morris, Jing Wang, David Gold, Lian-Chun Xiao, Kevin R. Coombes Jun 2003

A Comprehensive Approach To The Analysis Of Maldi-Tof Proteomics Spectra From Serum Samples., Keith A. Baggerly, Jeffrey S. Morris, Jing Wang, David Gold, Lian-Chun Xiao, Kevin R. Coombes

Jeffrey S. Morris

For our analysis of the data from the First Annual Proteomics Data Mining Conference, we attempted to discriminate between 24 disease spectra (group A) and 17 normal spectra (group B). First, we processed the raw spectra by (i) correcting for additive sinusoidal noise (periodic on the time scale) affecting most spectra, (ii) correcting for the overall baseline level, (iii) normalizing, (iv) recombining fractions, and (v) using variable- width windows for data reduction. Also, we identified a set of polymeric peaks (at multiples of 180.6 Da) that is present in several normal spectra (B1–B8). After data processing, we found ...


Evidence Of An Interaction Between Nifedipine And Nafcillin In Humans, Zahurin Mohamed Jun 2003

Evidence Of An Interaction Between Nifedipine And Nafcillin In Humans, Zahurin Mohamed

Zahurin Mohamed

Aims Nafcillin (Wyeth Laboratories, Philadelphia, PA, USA) has been reported to induce the metabolism of cyclosporin and warfarin, which are known substrates of cytochrome P-450 (CYP). However, there has not been any report to date on its possible interaction with nifedipine, an index substrate of the enzyme, CYP3A4. Methods Nine healthy normotensive subjects participated in this randomized placebo-controlled two-way crossover study examining the effects of 5 days' pretreatment of nafcillin 500 mg or placebo four times daily on the pharmacokinetics of an oral dose of nifedipine 10 mg. Plasma nifedipine concentrations were measured by gas chromatography-mass spectro. Results The area ...


Quelques Conseils À Nos Nouveau Diplomés, Fathi Habashi Jun 2003

Quelques Conseils À Nos Nouveau Diplomés, Fathi Habashi

Fathi Habashi

An advice, the old wise man Polonius offered to the young Hamlet was “Neither a borrower, nor a lender be”, may be no longer pertinent. Some more relevant advices are offered to new graduates of the twentieth century. Available in English, French, and Spanish


Bayesian Shrinkage Estimation Of The Relative Abundance Of Mrna Transcripts Using Sage, Jeffrey S. Morris, Keith A. Baggerly, Kevin R. Coombes Mar 2003

Bayesian Shrinkage Estimation Of The Relative Abundance Of Mrna Transcripts Using Sage, Jeffrey S. Morris, Keith A. Baggerly, Kevin R. Coombes

Jeffrey S. Morris

Serial analysis of gene expression (SAGE) is a technology for quantifying gene expression in biological tissue that yields count data that can be modeled by a multinomial distribution with two characteristics: skewness in the relative frequencies and small sample size relative to the dimension. As a result of these characteristics, a given SAGE sample may fail to capture a large number of expressed mRNA species present in the tissue. Empirical estimators of mRNA species’ relative abundance effectively ignore these missing species, and as a result tend to overestimate the abundance of the scarce observed species comprising a vast majority of ...


Bifunctional Abietadiene Synthase: Mutual Structural Dependence Of The Active Sites For Protonation-Initiated And Ionization-Initiated Cyclizations, Reuben J. Peters, Ora A. Carter, Yan Zhang, Brian W. Matthews, Rodney B. Croteau Mar 2003

Bifunctional Abietadiene Synthase: Mutual Structural Dependence Of The Active Sites For Protonation-Initiated And Ionization-Initiated Cyclizations, Reuben J. Peters, Ora A. Carter, Yan Zhang, Brian W. Matthews, Rodney B. Croteau

Reuben J. Peters

Abietadiene synthase from grand fir catalyzes two sequential, mechanistically distinct cyclizations, of geranylgeranyl diphosphate and of copalyl diphosphate, in the formation of a mixture of abietadiene isomers as the committed step of diterpenoid resin acid biosynthesis. Each reaction is independently conducted at a separate active site residing in what were considered to be structurally distinct domains typical of terpene cyclases. Despite the presence of an unusual 250-residue N-terminal insertional element, a tandem pair of charged residues distal to the insertion was shown to form a functional part of the C-terminal active site. Because abietadiene synthase resembles the ancestral plant terpene ...


Comparison Of Four Analytical Methods For The Determination Of Peroxide Value In Oxidized Soybean Oils, Gulgun (Yildiz) Tiryaki Feb 2003

Comparison Of Four Analytical Methods For The Determination Of Peroxide Value In Oxidized Soybean Oils, Gulgun (Yildiz) Tiryaki

Dr. Gülgün YILDIZ TIRYAKI

No abstract provided.


Dna Fingerprinting Abnormalities Can Distinguish Ulcerative Colitis Patients With Dysplasia And Cancer From Those Who Are Dysplasia/Cancer-Free , Ru Chen, Peter S. Rabinovitch, David A. Crispin, Mary J. Emond, Kent M. Koprowicz, Mary P. Bonner, Teresa A. Brentnall Feb 2003

Dna Fingerprinting Abnormalities Can Distinguish Ulcerative Colitis Patients With Dysplasia And Cancer From Those Who Are Dysplasia/Cancer-Free , Ru Chen, Peter S. Rabinovitch, David A. Crispin, Mary J. Emond, Kent M. Koprowicz, Mary P. Bonner, Teresa A. Brentnall

Kent M Koprowicz

No abstract provided.


Effects Of Aging On Vibration Detection Thresholds At Various Body Regions, Meg Stuart, A Bulent Turman, Jacqueline Shaw, Natalie Walsh, Vincent Nguyen Jan 2003

Effects Of Aging On Vibration Detection Thresholds At Various Body Regions, Meg Stuart, A Bulent Turman, Jacqueline Shaw, Natalie Walsh, Vincent Nguyen

Bulent Turman

Background
The ability to detect sinusoidal vibrations on the skin surface is dependent on the activation of two classes of receptors. The density of such receptors varies across the skin surface and is a factor in determining the sensory acuity of each skin area. However, the acuity of many sensory systems is known to deteriorate with advancing age. The aim of this study was to determine if vibrotactile sensibility of several skin surfaces deteriorated equally with advancing age.

Methods
Vibration detection thresholds for two frequencies of vibration (30 Hz and 200 Hz) were determined using a method of limits protocol ...


Clonal Propagation Of Tectona Grandis (Linn. F).: Effect Of Iba Application And Root Regeneration On Vertically Split Cuttings., Azamal Husen Dr., Mohinder Pal Jan 2003

Clonal Propagation Of Tectona Grandis (Linn. F).: Effect Of Iba Application And Root Regeneration On Vertically Split Cuttings., Azamal Husen Dr., Mohinder Pal

Dr. Azamal Husen

No abstract provided.


Effect Of Serial Bud Grafting And Etiolation On Rejuvenation And Rooting Of Mature Trees Of Tectona Grandis Linn.F., Azamal Husen Dr., Mohinder Pal Jan 2003

Effect Of Serial Bud Grafting And Etiolation On Rejuvenation And Rooting Of Mature Trees Of Tectona Grandis Linn.F., Azamal Husen Dr., Mohinder Pal

Dr. Azamal Husen

No abstract provided.


Effect Of Nitrogen, Phosphorous And Potassium Fertilizers On Growth Of Stock Plants Of Tectona Grandis (Linn. F.) And Rooting Behaviour Of Shoot Cuttings, Azamal Husen Dr., Mohinder Pal Jan 2003

Effect Of Nitrogen, Phosphorous And Potassium Fertilizers On Growth Of Stock Plants Of Tectona Grandis (Linn. F.) And Rooting Behaviour Of Shoot Cuttings, Azamal Husen Dr., Mohinder Pal

Dr. Azamal Husen

No abstract provided.


Further Evaluation Of A Multiplex Pcr For Differentiation Of Salmonella Paratyphi A From Other Salmonellae, Thong Kwai Lin Jan 2003

Further Evaluation Of A Multiplex Pcr For Differentiation Of Salmonella Paratyphi A From Other Salmonellae, Thong Kwai Lin

Thong Kwai Lin

Salmonella enterica serovar Paratyphi A is a causative agent of paratyphoid fever. The clinical syndrome caused by paratyphoid fever overlaps with other febrile illnesses and cannot be distinguished from typhoid fever. Conventional methods used for diagnosis are time consuming, costly, and labor-intensive. We evaluated the specificity, sensitivity, and application of a multiplex polymerase chain reaction (PCR) previously developed by the method (Ou, H.Y, Teh, C.S.J., Thong, K.L., et al., J. Mol. Diagn., 9, 624-630, 2007) using 6 S. Paratyphi A, 22 S. Typhi, and 85 other Salmonella serovars as well as 36 non-Salmonella strains. The detection ...


The Press For Help Project Concept, Program And Working Paper Of Emmanuel Mario B Santos And His Marc Guerrero Communications Inc., Emmanuel Mario B. Santos Aka Marc Guerrero Jan 2003

The Press For Help Project Concept, Program And Working Paper Of Emmanuel Mario B Santos And His Marc Guerrero Communications Inc., Emmanuel Mario B. Santos Aka Marc Guerrero

Emmanuel Mario B Santos aka Marc Guerrero

FORETHOUGHT. DECLARATION OF IDEAOLOGY AND PRINCIPLES. VISION. MISSION. VALUES. GOALS. BASIC HELP project. EDUCATIONAL HELP project. MEDICAL HELP project. LEGAL HELP project. EMERGENCY HELP project. LIVELIHOOD HELP project. SPIRITUAL and CULTURAL HELP project. ENVIRONMENTAL HELP project. REENGINEERING HELP project. INTERNATIONAL HELP project. QUADRO CREDO Matthew 5.1-12, the Jerusalem Bible. The Universal Filipino Beatitudes. SALIN SA FILIPINO. DESIDERATA. AFTERTHOUGHT.


From Alchemy To Atomic Bombs. Book Review By George Kauffman, Fathi Habashi Jan 2003

From Alchemy To Atomic Bombs. Book Review By George Kauffman, Fathi Habashi

Fathi Habashi

Review of the book "From Alchemy to Atomic Bombs" by Fathi Habashi published by Métallurgie Extractive Québec. The review is written by Professor George Kauffman at California State University, Fresno.


Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: I. Interactive Effects, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer Jan 2003

Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: I. Interactive Effects, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer

Steven P. Bradbury

This study explored the effects on Daphnia magna from exposure to the pesticide carbofuran in combination with stress from suspended solids exposure. Our objective was to assess whether suspended solids affects the toxicodynamic response of D. magna to carbofuran. A series of laboratory experiments was performed where animals were exposed to carbofuran concentrations ranging from 0 to 160 mg/l in combination with suspended solids concentrations ranging from 0 to 10,000 mg/l. In the absence of suspended solids, effects of carbofuran were dose dependent and resulted in an EC(sub)50 of 92 mg/l. Exposure to suspended ...


Quantitative Structure-Activity Relationship Models For Prediction Of Estrogen Receptor Binding Affinity Of Structurally Diverse Chemicals, Steven P. Bradbury, Patricia K. Schmeider, Gerald Ankley, Ovanes Mekenyan, John D. Walker Jan 2003

Quantitative Structure-Activity Relationship Models For Prediction Of Estrogen Receptor Binding Affinity Of Structurally Diverse Chemicals, Steven P. Bradbury, Patricia K. Schmeider, Gerald Ankley, Ovanes Mekenyan, John D. Walker

Steven P. Bradbury

The demonstrated ability of a variety of structurally diverse chemicals to bind to the estrogen receptor has raised the concern that chemicals in the environment may be causing adverse effects through interference with nuclear receptor pathways. Many structure–activity relationship models have been developed to predict chemical binding to the estrogen receptor as an indication of potential estrogenicity. Models based on either two-dimensional or three-dimensional molecular descriptions that have been used to predict potential for binding to the estrogen receptor are the subject of the current review. The utility of such approaches to predict binding potential of diverse chemical structures ...


Linear And Nonlinear Effects Of Habitat Structure On Composition And Abundance In The Macroinvertebrate Community Of A Large River, Timothy W. Stewart, Tammy L. Shumaker, Thomas A. Radzio Jan 2003

Linear And Nonlinear Effects Of Habitat Structure On Composition And Abundance In The Macroinvertebrate Community Of A Large River, Timothy W. Stewart, Tammy L. Shumaker, Thomas A. Radzio

Timothy W. Stewart

We used an experiment and regression analyses to quantify effects of spatial variation in habitat structure abundance on a riverine macroinvertebrate community under winter conditions. Concrete slabs (0.21 m2; n 5 24) with different numbers of stones (mean individual stone surface area 5 6.44 cm2) attached to upper faces were placed in the James River and retrieved after 28 d. Macroinvertebrate abundance and taxonomic richness on slabs were significantly positively related to stone abundance. Total macroinvertebrate abundance and abundance of oligochaetes (Nais spp.), Asiatic clams (Corbicula fluminea), caddisflies (Leptoceridae), riffle beetles (Elmidae) and stoneflies (Strophopteryx sp.) were linearly ...


Seventy Years Of Forest Change In The Northern Great Lakes Region, Usa, Lisa A. Schulte-Moore, Thomas R. Crow, Dave Cleland Jan 2003

Seventy Years Of Forest Change In The Northern Great Lakes Region, Usa, Lisa A. Schulte-Moore, Thomas R. Crow, Dave Cleland

Lisa A. Schulte Moore

The rates and magnitudes of forest change have important social and economic implications. We address facets of change associated with 20th century recovery of the U.S. Lake States (Michigan, Wisconsin, and Minnesota) forests from the Great Cutover, and discuss ecological and socioeconomic implications for future forest resources.


Overview Of Data And Conceptual Approaches For Derivation Of Quantitative Structure-Activity Relationships For Ecotoxicological Effects Of Organic Chemicals, Steven P. Bradbury, Christine L. Russom, Gerald T. Ankley, T. Wayne Schultz, John D. Walker Jan 2003

Overview Of Data And Conceptual Approaches For Derivation Of Quantitative Structure-Activity Relationships For Ecotoxicological Effects Of Organic Chemicals, Steven P. Bradbury, Christine L. Russom, Gerald T. Ankley, T. Wayne Schultz, John D. Walker

Steven P. Bradbury

The use of quantitative structure–activity relationships (QSARs) in assessing potential toxic effects of organic chemicals on aquatic organisms continues to evolve as computational efficiency and toxicological understanding advance. With the everincreasing production of new chemicals, and the need to optimize resources to assess thousands of existing chemicals in commerce, regulatory agencies have turned to QSARs as essential tools to help prioritize tiered risk assessments when empirical data are not available to evaluate toxicological effects. Progress in designing scientifically credible QSARs is intimately associated with the development of empirically derived databases of well-defined and quantified toxicity endpoints, which are based ...


An Overview Of The Use Of Quantitative Structure-Activity Relationships For Ranking And Prioritzing Large Chemical Inventories For Environmental Risk Assessments, Steven P. Bradbury, Christine L. Russom, Roger L. Breton, John D. Walker Jan 2003

An Overview Of The Use Of Quantitative Structure-Activity Relationships For Ranking And Prioritzing Large Chemical Inventories For Environmental Risk Assessments, Steven P. Bradbury, Christine L. Russom, Roger L. Breton, John D. Walker

Steven P. Bradbury

Ecological risk assessments for chemical stressors are used to establish linkages between likely exposure concentrations and adverse effects to ecological receptors. At times, it is useful to conduct screening risk assessments to assist in prioritizing or ranking chemicals on the basis of potential hazard and exposure assessment parameters. Ranking of large chemical inventories can provide evidence for focusing research and/or cleanup efforts on specific chemicals of concern. Because of financial and time constraints, data gaps exist, and the risk assessor is left with decisions on which models to use to estimate the parameter of concern. In this review, several ...


Qsar Prioritization Of Chemical Inventories For Endocrine Disruptor Testing, Steven P. Bradbury, Patricia Schmeider, Ovanes Mekenyan, Gilman Veith Jan 2003

Qsar Prioritization Of Chemical Inventories For Endocrine Disruptor Testing, Steven P. Bradbury, Patricia Schmeider, Ovanes Mekenyan, Gilman Veith

Steven P. Bradbury

Binding affinity between chemicals and the estrogen receptor (ER) serves as an indicator of the potential to cause endocrine disruption through this receptor-mediated endocrine pathway. Estimating ER-binding affinity is, therefore, one strategic approach to reducing the costs of screening chemicals for potential risks of endocrine disruption. While measuring ER binding with in vitro assays may be the first choice in prioritizing chemicals for additional in vitro or in vivo estrogenicity testing, the time and costs associated with screening thousands of chemicals is prohibitive. Recent advances in 3D modeling of the reactivity of flexible structures make in silico methods for estimating ...


Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: Ii. An Evaluation Of Potential Interactive Mechanisms, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer Jan 2003

Influence Of Suspended Solids On Acute Toxicity Of Carbofuran To Daphnia Magna: Ii. An Evaluation Of Potential Interactive Mechanisms, Steven P. Bradbury, Carl Herbrandson, Deborah L. Swackhamer

Steven P. Bradbury

It has been demonstrated that simultaneous exposure of Daphnia magna to suspended solids and a carbamate pesticide potentiates the toxic response to the pesticide. The toxicodynamics between these stressors were investigated to determine possible mechanisms of interaction. Three experimental series were conducted with D. magna to determine: the effect of food availability on carbofuran toxicity; the effect of food availability on jointly administered carbofuran and suspended solids; and changes in the magnitude of effects which can occur with suspended solids of different composition. These experiments demonstrated that both carbofuran toxicity and the joint toxicity of carbofuran and suspended solids to ...