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California Polytechnic State University, San Luis Obispo

Series

2010

Articles 1 - 30 of 98

Full-Text Articles in Life Sciences

Adaptive Divergence In The Thyroid Hormone Signaling Pathway In The Stickleback Radiation, Jun Kitano, Sean C. Lema, J. Adam Luckenbach, Seiichi Mori, Yui Kawagishi, Makoto Kusakabe, Penny Swanson, Catherine L. Peichel Dec 2010

Adaptive Divergence In The Thyroid Hormone Signaling Pathway In The Stickleback Radiation, Jun Kitano, Sean C. Lema, J. Adam Luckenbach, Seiichi Mori, Yui Kawagishi, Makoto Kusakabe, Penny Swanson, Catherine L. Peichel

Biological Sciences

During adaptive radiations, animals colonize diverse environments, which requires adaptation in multiple phenotypic traits. Because hormones mediate the dynamic regulation of suites of phenotypic traits, evolutionary changes in hormonal signaling pathways might contribute to adaptation to new environments. Here we report changes in the thyroid hormone signaling pathway in stream-resident ecotypes of threespine stickleback fish (Gasterosteus aculeatus), which have repeatedly evolved from ancestral marine ecotypes. Stream-resident fish exhibit a lower plasma concentration of thyroid hormone and a lower metabolic rate, which is likely adaptive for permanent residency in small streams. The thyroid-stimulating hormone-β2 (TSHβ2) gene exhibited ...


Dual Inhibition Of Sodium-Mediated Proton And Calcium Efflux Triggers Non-Apoptotic Cell Death In Malignant Gliomas, William Harley, Candace Floyd, Tamara Dunn, Xiao-Dong Zhang, Tsung-Yu Chen, Manu Hegde, Hasan Palandoken, Michael H. Nantz, Leonardo Leon, K.L. Carraway Iii, Bruce Lyeth, Fredric A. Gorin Dec 2010

Dual Inhibition Of Sodium-Mediated Proton And Calcium Efflux Triggers Non-Apoptotic Cell Death In Malignant Gliomas, William Harley, Candace Floyd, Tamara Dunn, Xiao-Dong Zhang, Tsung-Yu Chen, Manu Hegde, Hasan Palandoken, Michael H. Nantz, Leonardo Leon, K.L. Carraway Iii, Bruce Lyeth, Fredric A. Gorin

Chemistry and Biochemistry

Malignant glioma cells maintain an elevated intracellular pH (pHi) within hypoxic–ischemic tumormicroenvironments through persistent activation of sodium–proton transport (McLean et al., 2000). Amiloride has been reported to selectively kill human malignant glioma cell lines but not primary astrocytes (Hegde et al., 2004). While amiloride reduces pHi of malignant gliomas by inhibiting isoform 1 of sodium–proton exchange (NHE1), direct acidification was shown to be cytostatic rather than cytotoxic. At cytotoxic concentrations, amiloride has multiple drug targets including inhibition of NHE1 and sodium–calciumexchange. Amiloride's glioma cytotoxicity can be explained, at least in part, by dual ...


Prevalence And Predictors Of Weight-Loss Maintenance In A Biracial Cohort: Results From The Coronary Artery Risk Development In Young Adults Study, Suzanne Phelan, Rena R. Wing, Catherine M. Loria, Yongin Kim, Cora E. Lewis Dec 2010

Prevalence And Predictors Of Weight-Loss Maintenance In A Biracial Cohort: Results From The Coronary Artery Risk Development In Young Adults Study, Suzanne Phelan, Rena R. Wing, Catherine M. Loria, Yongin Kim, Cora E. Lewis

Kinesiology

Background: Few population-based studies have examined the behavioral and psychosocial predictors of long-term weight-loss maintenance.
Purpose: The goal of this study was to determine the prevalence and predictors of weight-loss maintenance in a biracial cohort of younger adults.
Methods: This study examined a population-based sample of overweight/obese African-American and white men and women who had 5% weight loss between 1995 and 2000. Subsequent changes in weight, physical activity, and behavioral and psychosocial factors were examined between 2000 and 2005. Analyses were conducted in 2008 –2009.
Results: Among the 1869 overweight/obese individuals without major disease in 1995, a total ...


Flowering Locus C Influences The Timing Of Shoot Maturation In Arabidopsis Thaliana, Laurie Mentzer, Tarah Yee, Tina Y. Wang, Edward Himelblau Dec 2010

Flowering Locus C Influences The Timing Of Shoot Maturation In Arabidopsis Thaliana, Laurie Mentzer, Tarah Yee, Tina Y. Wang, Edward Himelblau

Biological Sciences

No abstract provided.


Food Processors Look To Dairy Ingredients, Phillip S. Tong Dec 2010

Food Processors Look To Dairy Ingredients, Phillip S. Tong

Dairy Science

No abstract provided.


The Influence Of Persistent Pathogens On Circulating Levels Of Inflammatory Markers: A Cross-Sectional Analysis From The Multi-Ethnic Study Of Atherosclerosis, Aydin Nazmi, Ana V. Diez-Roux, Nancy S. Jenny, Michael Y. Tsai, Moyses Szklo, Allison E. Aiello Nov 2010

The Influence Of Persistent Pathogens On Circulating Levels Of Inflammatory Markers: A Cross-Sectional Analysis From The Multi-Ethnic Study Of Atherosclerosis, Aydin Nazmi, Ana V. Diez-Roux, Nancy S. Jenny, Michael Y. Tsai, Moyses Szklo, Allison E. Aiello

Food Science and Nutrition

Background: Systemic inflammation is linked to cardiovascular risk, but the influence of persistent pathogens, which are conventionally dichotomously categorized, on circulating levels of inflammatory markers is not clear. Antibody levels of pathogens have not been examined in relation to inflammation.
Methods: Using data from a subsample of the Multi-Ethnic Study of Atherosclerosis, we examined circulating levels of interleukin-6 (IL-6), C-reactive protein (CRP) and fibrinogen in relation to five common persistent pathogens: cytomegalovirus, herpes simplex virus-1, Hepatitis A virus, Helicobacter pylori and Chlamydia pneumoniae. We tested the hypothesis that the number of seropositive pathogens (based on conventional cut-off points) would not ...


Cross-Sectional And Longitudinal Associations Of Neighborhood Characteristics With Inflammatory Markers: Findings From The Multi-Ethnic Study Of Atherosclerosis, Aydin Nazmi, Ana Diez Roux, Nalini Ranjit, Teresa E. Seeman, Nancy S. Jenny Nov 2010

Cross-Sectional And Longitudinal Associations Of Neighborhood Characteristics With Inflammatory Markers: Findings From The Multi-Ethnic Study Of Atherosclerosis, Aydin Nazmi, Ana Diez Roux, Nalini Ranjit, Teresa E. Seeman, Nancy S. Jenny

Food Science and Nutrition

We investigated cross-sectional associations of neighborhood deprivation, problems, safety, and cohesion with circulating levels of fibrinogen, interleukin-6, and C-reactive protein (n=5370) and longitudinal associations with changes in IL-6 over a 3–4 year period (n=946). In cross-sectional analyses, higher levels of neighborhood deprivation and problems were associated with higher levels of all three inflammatory markers, whereas higher levels of safety were associated with lower levels. Fibrinogen remained associated with all neighborhood characteristics except cohesion and IL-6 remained associated with safety after adjustment for race and SES. In longitudinal analyses, higher levels of neighborhood deprivation and problems, and lower ...


Designing Marine Reserve Networks For Both Conservation And Fisheries Management, Steven D. Gaines, Crow White, Mark H. Carr, Stephen R. Palumbi Oct 2010

Designing Marine Reserve Networks For Both Conservation And Fisheries Management, Steven D. Gaines, Crow White, Mark H. Carr, Stephen R. Palumbi

Biological Sciences

Marine protected areas (MPAs) that exclude fishing have been shown repeatedly to enhance the abundance, size, and diversity of species. These benefits, however, mean little to most marine species, because individual protected areas typically are small. To meet the larger-scale conservation challenges facing ocean ecosystems, several nations are expanding the benefits of individual protected areas by building networks of protected areas. Doing so successfully requires a detailed understanding of the ecological and physical characteristics of ocean ecosystems and the responses of humans to spatial closures. There has been enormous scientific interest in these topics, and frameworks for the design of ...


Evaluation Of School Wellness Policies In North San Luis Obispo County (Final Report), Ann Yelmokas Mcdermott, David W. Hey, Laurie Pugh, Rosanna Taylor, Arlene Grant-Holcomb, Stephanie F. Teaford Oct 2010

Evaluation Of School Wellness Policies In North San Luis Obispo County (Final Report), Ann Yelmokas Mcdermott, David W. Hey, Laurie Pugh, Rosanna Taylor, Arlene Grant-Holcomb, Stephanie F. Teaford

Kinesiology

A two year grant (October 2008-2010) was awarded to the San Luis Obispo County Public Health Department (SLO-PHD) so that outside agencies could engage in school wellness policy (SWP) advocacy and community activities to aid in combating the growing epidemic of obesity among the county‘s high risk populations. Under SLO-PHD oversight, Healthy Eating Active Living (HEAL-SLO) proposed school district outcomes, objectives, and indicators. (Attachment A provides the SWP rationale while Attachment B contains the HEAL-SLO/TCE purpose and goals.) In March 2009, a research team from newly formed STRIDE at California Polytechnic State University was contracted to review and ...


A Novel Method For Evaluating The Release Of Fermentable Sugars From Cellulosic Biomass, Rafael Jiménez-Flores, Gina Fake, Jennifer Carroll, Elizabeth Hood, John Howard Oct 2010

A Novel Method For Evaluating The Release Of Fermentable Sugars From Cellulosic Biomass, Rafael Jiménez-Flores, Gina Fake, Jennifer Carroll, Elizabeth Hood, John Howard

Dairy Science

Efficient hydrolysis of cellulosic biomass into free sugars for the production of bioethanol would allow utilization of an abundant and renewable natural resource. However, complex microcrystalline cellulose in biomass resists digestion. A preferred method to deconstruct cellulose is using enzyme cocktails, but the presence of multiple enzymes with synergistic outcomes for this process complicates direct biochemical analysis as a reliable indicator of deconstruction. Methods to detect release of free sugars rather than direct measurement of enzymatic activity are available but are time-consuming, and do not reflect the production of metabolic inhibitors of microbial growth which may interfere with the subsequent ...


Lutein Exposure, In Ovo Or In The Diet, Reduces Parameters Of Inflammation In The Liver And Spleen Laying-Type Chicks (Gallus Gallus Domesticus), L.S. Meriwether, B. D. Humphrey, D. G. Peterson, K. C. Klasing, E. A. Koutsos Oct 2010

Lutein Exposure, In Ovo Or In The Diet, Reduces Parameters Of Inflammation In The Liver And Spleen Laying-Type Chicks (Gallus Gallus Domesticus), L.S. Meriwether, B. D. Humphrey, D. G. Peterson, K. C. Klasing, E. A. Koutsos

Animal Science

These trials examined whether the demonstrated effects of embryonic and dietary carotenoid exposure on the inflammatory immune response in fast growing chickens also occur in slow growing chickens. The systemic and local inflammatory responses of chicks were examined in two experiments with two in ovo lutein levels (C+, carotenoid replete; or C−, carotenoid-deplete), two dietary lutein levels (0 or 40 mg lutein/kg diet), and two inflammatory challenges [no exposure or lipopolysaccharide (LPS)-vaccinated]. At 24 h after LPS vaccination, spleen weight was not affected by diet or in ovo lutein, but liver weight increased from C+ eggs (p < 0.01), and in LPS-vaccinated chicks fed 0 mg lutein (p < 0.05), but not in chicks fed 40 mg lutein. Plasma carotenoids and liver carotenoids were reduced post-LPS (p < 0.05). Splenic IL-6 mRNA abundance was the greatest post-LPS in C− chicks fed 40 mg lutein vs. C+ chicks fed 40 mg lutein (p < 0.05). Hepatic IL-6, iNOS and TGFβ and splenic iNOS and TGFβ ...


Solving The Low Dimensional Smoluchowski Equation With A Singular Value Basis Set, Gregory E. Scott, Martin Gruebele Oct 2010

Solving The Low Dimensional Smoluchowski Equation With A Singular Value Basis Set, Gregory E. Scott, Martin Gruebele

Chemistry and Biochemistry

Reaction kinetics on free energy surfaces with small activation barriers can be computed directly with the Smoluchowski equation. The procedure is computationally expensive even in a few dimensions. We present a propagation method that considerably reduces computational time for a particular class of problems: when the free energy surface suddenly switches by a small amount, and the probability distribution relaxes to a new equilibrium value. This case describes relaxation experiments. To achieve efficient solution, we expand the density matrix in a basis set obtained by singular value decomposition of equilibrium density matrices. Grid size during propagation is reduced from (100 ...


Evaluation Of School Wellness Policies In South San Luis Obispo County (Final Report), Ann Yelmokas Mcdermott, David W. Hey, Laurie Pugh, Rosanna Taylor, Arlene Grant-Holcomb, Stephanie F. Teaford Sep 2010

Evaluation Of School Wellness Policies In South San Luis Obispo County (Final Report), Ann Yelmokas Mcdermott, David W. Hey, Laurie Pugh, Rosanna Taylor, Arlene Grant-Holcomb, Stephanie F. Teaford

Kinesiology

A two year grant (October 2008-2010) was awarded to the San Luis Obispo County Public Health Department (SLO-PHD) so that outside agencies could engage in school wellness policy (SWP) advocacy and community activities to aid in combating the growing epidemic of obesity among the county’s high risk populations. Under SLO-PHD oversight, Healthy Eating Active Living (HEAL-SLO) proposed school district outcomes, objectives, and indicators. (Attachment A provides the SWP rationale while Attachment B contains the HEAL-SLO/TCE purpose and goals.) In March 2009, a research team from the newly formed STRIDE at California Polytechnic State University was contracted to review ...


Delivering Health And Wellness, Phillip S. Tong Sep 2010

Delivering Health And Wellness, Phillip S. Tong

Dairy Science

No abstract provided.


Nonylphenol In Marine Organisms In North American Estuaries: Trophic Chain Accumulation And Proteomic Responses, Lars Tomanek, J. M. Diehl, S. E. Johnson, K. Xia, S. J. Teh Sep 2010

Nonylphenol In Marine Organisms In North American Estuaries: Trophic Chain Accumulation And Proteomic Responses, Lars Tomanek, J. M. Diehl, S. E. Johnson, K. Xia, S. J. Teh

Biological Sciences

No abstract provided.


The Role Of Oxidative Stress In Setting Thermal Tolerance Limits In Mytilus, Lars Tomanek Sep 2010

The Role Of Oxidative Stress In Setting Thermal Tolerance Limits In Mytilus, Lars Tomanek

Biological Sciences

No abstract provided.


Novel Polymer Coupling Chemistry Based Upon Latent Cysteine-Like Residues And Thiazolidine Chemistry, Jospeh S. Carlson, Megan R. Hill, Taiga Young, Philip Costanzo Aug 2010

Novel Polymer Coupling Chemistry Based Upon Latent Cysteine-Like Residues And Thiazolidine Chemistry, Jospeh S. Carlson, Megan R. Hill, Taiga Young, Philip Costanzo

Chemistry and Biochemistry

Chain end functional polymers were prepared via reversible addition–fragmentation transfer (RAFT) polymerization techniques that were further chain extended with acrylonitrile. Under reducing conditions, latent cysteine-like residues were exposed at the chain ends. A variety of reduction conditions were explored and base polymers were then tethered together via thiazolidine chemistry.


Preventative Fungicide Applications For Control Of Dollar Spot And Brown Patch On Creeping Bentgrass In Kansas, 2009, M Kennelly, C Thompson Aug 2010

Preventative Fungicide Applications For Control Of Dollar Spot And Brown Patch On Creeping Bentgrass In Kansas, 2009, M Kennelly, C Thompson

Horticulture and Crop Science

No abstract provided.


Preventative Fungicide Applications For Control Of Dollar Spot And Brown Patch On Creeping Bentgrass In Kansas, 2009, M Kennelly, C Thompson Aug 2010

Preventative Fungicide Applications For Control Of Dollar Spot And Brown Patch On Creeping Bentgrass In Kansas, 2009, M Kennelly, C Thompson

Horticulture and Crop Science

No abstract provided.


Notonecta Exhibit Threat-Sensitive, Predator-Induced Dispersal, Shannon J. Mccauley, Locke Rowe Aug 2010

Notonecta Exhibit Threat-Sensitive, Predator-Induced Dispersal, Shannon J. Mccauley, Locke Rowe

Biological Sciences

Dispersal is a central process determining community structure in heterogeneous landscapes, and species interactions within habitats may be a major determinant of dispersal. Although the effects of species interactions on dispersal within habitats have been well studied, how species interactions affect the movement of individuals between habitats in a landscape has received less attention. We conducted two experiments to assess the extent to which predation risk affects dispersal from an aquatic habitat by a flight-capable semi-aquatic insect (Notonecta undulata). Exposure to non-lethal (caged) fish fed conspecifics increased dispersal rates in N. undulata. Moreover, dispersal rate was positively correlated with the ...


Pismo Beach Fecal Contamination Source Identification Study: Final Report, Christopher L. Kitts, Michael W. Black, Mark M. Moline, Marie Yeung, Alice K. Hamrick, Ian C. Robbins, Andrew A. Schaffner, Nathania I. Boutet Aug 2010

Pismo Beach Fecal Contamination Source Identification Study: Final Report, Christopher L. Kitts, Michael W. Black, Mark M. Moline, Marie Yeung, Alice K. Hamrick, Ian C. Robbins, Andrew A. Schaffner, Nathania I. Boutet

Biological Sciences

No abstract provided.


The Impact Of Antioxidant Addition On Flavor Of Cheddar And Mozzarella Whey And Cheddar Whey Protein Concentrate, I. W. Liaw, H. Eshpari, P. S. Tong, M. A. Drake Aug 2010

The Impact Of Antioxidant Addition On Flavor Of Cheddar And Mozzarella Whey And Cheddar Whey Protein Concentrate, I. W. Liaw, H. Eshpari, P. S. Tong, M. A. Drake

Dairy Science

Lipid oxidation products are primary contributors to whey ingredient off-flavors. The objectives of this study were to evaluate the impact of antioxidant addition in prevention of flavor deterioration of fluid whey and spray-dried whey protein. Cheddar and Mozzarella cheeses were manufactured in triplicate. Fresh whey was collected, pasteurized, and defatted by centrifugal separation. Subsequently, 0.05% (w/w) ascorbic acid or 0.5% (w/w) whey protein hydrolysate (WPH) were added to the pasteurized whey. A control with no antioxidant addition was also evaluated. Wheys were stored at 3 °C and evaluated after 0, 2, 4, 6, and 8 d ...


Turning Crocodilian Hearts Into Bird Hearts: Growth Rates Are Similar For Alligators With And Without Right-To-Left Cardiac Shunt, John Eme, June Gwalthney, Tomasz Owerkowicz, Jason M. Blank, James W. Hicks Aug 2010

Turning Crocodilian Hearts Into Bird Hearts: Growth Rates Are Similar For Alligators With And Without Right-To-Left Cardiac Shunt, John Eme, June Gwalthney, Tomasz Owerkowicz, Jason M. Blank, James W. Hicks

Biological Sciences

The functional and possible adaptive significance of non-avian reptiles’ dual aortic arch system and the ability of all non-avian reptiles to perform central vascular cardiac shunts have been of great interest to comparative physiologists. The unique cardiac anatomy of crocodilians – a four-chambered heart with the dual aortic arch system – allows for only right-to-left (R–L; pulmonary bypass) cardiac shunt and for surgical elimination of this shunt. Surgical removal of the R–L shunt, by occluding the left aorta (LAo) upstream and downstream of the foramen of Panizza, results in a crocodilian with an obligatory, avian/mammalian central circulation. In this ...


Sierra Nevada Red Fox (Vulpes Vulpes Necator): A Conservation Assessment, John D. Perrine, Lori A. Campbell, Gregory A. Green Aug 2010

Sierra Nevada Red Fox (Vulpes Vulpes Necator): A Conservation Assessment, John D. Perrine, Lori A. Campbell, Gregory A. Green

Biological Sciences

One goal of the Sierra Nevada Forest Plan Amendment (SNFPA) 2001 and 2004 Records of Decision was to protect and recover native Sierra Nevada red fox (Vulpes vulpes necator) populations in the Sierra Nevada (USDA Forest Service 2001 p. 14). To accomplish this goal, the ROD commits the U.S. Department of Agriculture (USDA) Forest Service to completing a conservation assessment for the Sierra Nevada red fox in cooperation with other federal, state, and local agencies, as well as Tribal governments. This conservation assessment synthesizes the best available scientific information and thought concerning habitat relationships, population status and trends, historical ...


Barnacle Settlement And The Adhesion Of Protein And Diatom Microfouling To Xerogel Films With Varying Surface Energy And Water Wettability, John A. Finlay, Stephanie M. Bennett, Lenora H. Brewer, Anastasiya Sokolova, Gemma Clay, Nikhil Gunari, Anne E. Meyer, Gilbert C. Walker, Dean E. Wendt, Maureen E. Callow, James A. Callow, Michael R. Detty Jul 2010

Barnacle Settlement And The Adhesion Of Protein And Diatom Microfouling To Xerogel Films With Varying Surface Energy And Water Wettability, John A. Finlay, Stephanie M. Bennett, Lenora H. Brewer, Anastasiya Sokolova, Gemma Clay, Nikhil Gunari, Anne E. Meyer, Gilbert C. Walker, Dean E. Wendt, Maureen E. Callow, James A. Callow, Michael R. Detty

Biological Sciences

Previous work has shown that organosilica-based xerogels have the potential to control biofouling. In this study, modifications of chemistry were investigated with respect to their resistance to marine slimes and to settlement of barnacle cyprids. Adhesion force measurements of bovine serum albumin (BSA)-coated atomic force microscopy (AFM) tips to xerogel surfaces prepared from aminopropylsilyl-, fluorocarbonsilyl-, and hydrocarbonsilyl-containing precursors, indicated that adhesion was significantly less on the xerogel surfaces in comparison to a poly(dimethylsiloxane) elastomer (PDMSE) standard. The strength of adhesion of BSA on the xerogels was highest on surfaces with the highest and the lowest critical surface tensions ...


Effects On Lactation Performance When Slick Hair Gene Is Simulated In Dairy Cattle In The Tropics, R. M. Mejía, J. A. Ortuño, G. J. Lascano, M. Vélez Jul 2010

Effects On Lactation Performance When Slick Hair Gene Is Simulated In Dairy Cattle In The Tropics, R. M. Mejía, J. A. Ortuño, G. J. Lascano, M. Vélez

Dairy Science

No abstract provided.


Digestibility Of Fresh Sugarcane-Based Diets With Slow-Release Non Protein Nitrogen Addition For Limit-Fed Dairy Heifers In The Tropics, G. J. Lascano, M. Velez, J. M. Tricarico, A. J. Heinrichs Jul 2010

Digestibility Of Fresh Sugarcane-Based Diets With Slow-Release Non Protein Nitrogen Addition For Limit-Fed Dairy Heifers In The Tropics, G. J. Lascano, M. Velez, J. M. Tricarico, A. J. Heinrichs

Dairy Science

No abstract provided.


Nutrient Utilization Of Different Levels Of Dietary Fiber In Dairy Heifers Limit-Fed High And Low Concentrate Diets, G. J. Lascano, A. J. Heinrichs Jul 2010

Nutrient Utilization Of Different Levels Of Dietary Fiber In Dairy Heifers Limit-Fed High And Low Concentrate Diets, G. J. Lascano, A. J. Heinrichs

Dairy Science

No abstract provided.


Dietary Starch Level And Dose Response Of Saccharomyces Cerevisiae For Limit Fed-Dairy Heifers, G. J. Lascano, J. M. Tricarico, A. J. Heinrichs Jul 2010

Dietary Starch Level And Dose Response Of Saccharomyces Cerevisiae For Limit Fed-Dairy Heifers, G. J. Lascano, J. M. Tricarico, A. J. Heinrichs

Dairy Science

No abstract provided.


Low Vitamin D Status Is Associated With Physical Inactivity, Obesity And Low Vitamin D Intake In A Large Us Sample Of Healthy Middle-Aged Men And Women, K. Brock, W. Y. Huang, D. R. Fraser, L. Ke, M. Tseng, R. Stolzenberg-Solomon, U. Peters, J. Ahn, M. Purdue, R. S. Mason, C. Mccarty, R. G. Ziegler, B. Graubard Jul 2010

Low Vitamin D Status Is Associated With Physical Inactivity, Obesity And Low Vitamin D Intake In A Large Us Sample Of Healthy Middle-Aged Men And Women, K. Brock, W. Y. Huang, D. R. Fraser, L. Ke, M. Tseng, R. Stolzenberg-Solomon, U. Peters, J. Ahn, M. Purdue, R. S. Mason, C. Mccarty, R. G. Ziegler, B. Graubard

Kinesiology

The aim of this study was to investigate modifiable predictors of vitamin D status in healthy individuals, aged 55–74, and living across the USA. Vitamin D status [serum 25-hydroxyvitamin D (25(OH)D)] was measured along with age and season at blood collection, demographics, anthropometry, physical activity (PA), diet, and other lifestyle factors in 1357 male and 1264 female controls selected from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort. Multivariate linear and logistic regression analyses were used to identify associations with vitamin D status. Three%, 29% and 79% of the population had serum 25(OH ...