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California Polytechnic State University, San Luis Obispo

Series

Food Science and Nutrition

1999

Articles 1 - 1 of 1

Full-Text Articles in Life Sciences

Interaction Of Blood Pressure And Ldl Cholesterol In Early Atherosclerosis. The Los Angeles Atherosclerosis Study, Ping Sun, Kathleen M. Dwyer, Noel Bairey Merz, Wei Sun, Lisa M. Nicholson, Cheryl Nordstrom, James H. Dwyer Jan 1999

Interaction Of Blood Pressure And Ldl Cholesterol In Early Atherosclerosis. The Los Angeles Atherosclerosis Study, Ping Sun, Kathleen M. Dwyer, Noel Bairey Merz, Wei Sun, Lisa M. Nicholson, Cheryl Nordstrom, James H. Dwyer

Food Science and Nutrition

Background. The response to injury model of atherosclerosis has been investigated in animal models but not in epidemiologic studies. Relations between LDL cholesterol and carotid intima-media thickness (IMT) within levels of SBP provide a test of this model. Methods. Data are from a longitudinal study of 573 randomly sampled asymptomatic employees of a large company aged 40-60 years. IMT and change in IMT over 18 months (8IMT) were determined sonographically in the common carotid artery. 497 subjects were available for cross-sectional analysis. To investigate interactive effects of SBP and serum LDL on IMT, linear slopes (j±SE in mm/mmol ...