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Theses/Dissertations

Health and environmental sciences

University of Windsor

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Articles 1 - 4 of 4

Full-Text Articles in Life Sciences

Engagement Of Seniors: 'How' And 'Why' Engagement Profiles Change Over Time, Kelly Carr Jan 2014

Engagement Of Seniors: 'How' And 'Why' Engagement Profiles Change Over Time, Kelly Carr

Electronic Theses and Dissertations

This study explored 'how' and 'why' engagement profiles change throughout older adulthood within a framework of successful aging. A convergent parallel mixed methods design was employed. Fifty-four participants (mean age = 79.17, age range = 65-97 years; 21 males, 33 females) completed questionnaires to quantify 'past' and 'present' engagement. Focus groups segmented by decade of life and semi-structured interviews were completed with a subsample of participants (n = 42). Results indicated that participation in productive and active leisure activities decreased with increasing age, while social and passive leisure engagement remained stable. This change in engagement pattern may be a function of the ...


Effectiveness Of Commercial Video Gaming On Fine Motor Recovery In Chronic Stroke Within Community-Level Rehabilitation, Kathleen C. Paquin Jan 2014

Effectiveness Of Commercial Video Gaming On Fine Motor Recovery In Chronic Stroke Within Community-Level Rehabilitation, Kathleen C. Paquin

Electronic Theses and Dissertations

Introduction: Chronic stroke survivors often live with persisting upper extremity deficits that affect their daily life, and are traditionally offered little rehabilitation. Commercial gaming can act as a motivating way to complete rehabilitation. Purpose: To investigate the effectiveness of commercial gaming as an intervention for fine motor recovery in chronic stroke. Methods: Ten chronic phase post-stroke participants completed a 16-session program using the Nintendo Wii for 15 minutes 2x/week with their more affected hand. Measures used at four testing sessions included: Jebsen Hand Function Test (JHFT), Box and Blocks Test (BBT), Nine Hole Peg Test (NHPT), Stroke Impact Scale ...


Exploring New Capacities For Pitx3 During Xenopus Embryogenesis, Lara Nicole Hooker Jan 2012

Exploring New Capacities For Pitx3 During Xenopus Embryogenesis, Lara Nicole Hooker

Electronic Theses and Dissertations

Pitx3 encodes a homeodomain transcription factor that represents the causative locus for the aphakia phenotype in mouse as well as congenital cataracts and anterior segment mesenchymal dysgenesis in humans. Mutations in Pitx3 can also lead to the development of Parkinson's disease. A conserved role for Pitx3 has been established in the terminal differentiation and maintenance of lens fibres and dopaminergic neurons within the midbrain. Pitx3 has also been reported to contribute to skeletal muscle differentiation in mice. Through the use of morpholino-mediated knockdown, the Xenopus model system has allowed further refining of putative roles for pitx3 during embryogenesis. We ...


Novel Targets And Functions For Xenopus Pitx3 During Embryonic Development, Cristine Smoczer Jan 2012

Novel Targets And Functions For Xenopus Pitx3 During Embryonic Development, Cristine Smoczer

Electronic Theses and Dissertations

Pitx3 is a homeodomain transcription factor with an expression pattern conserved across phyla: in the dopaminergic neurons of the midbrain, in the lens during all stages of lens development and in the forming somites. In Xenopus laevis, this gene shows novel expression areas, such as the pituitary gland, the heart and the gut. Morpholino-based knockdown of pitx3 results in phenotypes characterized by small or absent lens, bent dorsal axis and randomized coiling of the heart and gut. Comparing gene expression changes in wild-type versus knockdown embryos by microarray, we generated a vast list of genes possible downstream targets for pitx3 ...