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Theses/Dissertations

2013

Chemistry

Ouachita Baptist University

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Full-Text Articles in Life Sciences

My Experience Exploring The Effects Of Lead (Pb +2) Toxicity In Drosophila Melanogaster Using Sociability Interaction Testing And Microarrays At The University Of Puerto Rico-Rio Piedras In San Juan, Puerto Rico, Charlton Diaz Jan 2013

My Experience Exploring The Effects Of Lead (Pb +2) Toxicity In Drosophila Melanogaster Using Sociability Interaction Testing And Microarrays At The University Of Puerto Rico-Rio Piedras In San Juan, Puerto Rico, Charlton Diaz

Honors Theses

Lead is an environmental contaminant widely dispersed throughout the world. Exposure to lead causes neurological damage in humans and may be linked to neurodevelopmental pathologies such as attention deficit hyperactivity disorder, antisocial behavior, and autistic spectrum disorders (ASD). Drosophila melanogaster (fruit flies) have been used to understand the behavioral, synaptic, and molecular changes that occur after developmental exposure to lead and to study ASD-associated pathology. Flies were exposed through the mother and until eclosion to either a lead-laced medium or a control corn-based medium and were isolated until the beginning for the behavioral studies. Sociability testing was done using a ...